A5028389199- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Renal Transplantation Outcomes and Treatments
- Cardiovascular Function and Risk Factors
- Viral Infections and Immunology Research
- Hemoglobinopathies and Related Disorders
- Organ Transplantation Techniques and Outcomes
- Pulmonary Hypertension Research and Treatments
- Iron Metabolism and Disorders
- Cardiovascular and exercise physiology
- Cardiovascular Effects of Exercise
- Cardiovascular Issues in Pregnancy
- Neonatal Respiratory Health Research
- Cardiomyopathy and Myosin Studies
- Cardiac pacing and defibrillation studies
- Cardiac Arrest and Resuscitation
- Congenital Anomalies and Fetal Surgery
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Ethics and Legal Issues in Pediatric Healthcare
- Pneumocystis jirovecii pneumonia detection and treatment
- Blood groups and transfusion
- Tracheal and airway disorders
Cincinnati Children's Hospital Medical Center
2016-2025
University of Cincinnati
2013-2023
Vanderbilt University
2023
University of Cincinnati Medical Center
2016-2023
Vanderbilt University Medical Center
2021-2022
Monroe Carell Jr. Children's Hospital
2022
Children's Medical Center
2019-2021
National Heart Institute
2018
Boston Children's Hospital
2012
Hospital for Sick Children
2012
Background— The importance of clinical presentation and pretransplantation course on outcome in children with dilated cardiomyopathy listed for heart transplantation is not well defined. Methods Results— impact age, duration illness, sex, race, ventricular geometry, diagnosis myocarditis 261 enrolled the Pediatric Cardiomyopathy Registry Heart Transplant Study was studied. End points included listing as United Network Organ Sharing status 1, death while waiting, after transplantation. median...
Background Adults with a Fontan circulation tend to have myopenia and elevated adiposity when measured by dual energy x-ray absorptiometry. Bioelectrical impedance analysis is an alternative validated approach assess body composition. We used bioelectrical compare composition between pediatric patients control individuals without heart disease. Methods Results A retrospective chart review identified all aged <22 years who presented for cardiopulmonary exercise testing from April 2019 January...
Background With an increasing number of Fontan patients surviving into adulthood, the burden end-stage heart failure is increasing. Prior studies have reported suboptimal transplantation (HTx) outcomes. Therefore, authors describe their institutional experience HTx in with circulation failure, including en-bloc heart-liver (HLTx) and pretransplant systemic ventricular assist device (SVAD) therapies. Methods All consecutive Fontan-palliated undergoing or HLTx between 2013 2022 at authors’...
Abstract The relationship between SES and outcomes surrounding pediatric cardiac transplantation is complex influenced by recipient race. Broad‐based studies of have not been performed. A retrospective review all 5125 primary heart transplants performed in the U nited S tates 2000 2011. Patients were stratified based on zip code residence . census data (low : 1637; mid‐ 2253; high 1235). Survival following listing was compared across strata. Risk‐adjusted long‐term mortality waitlist higher...
ABSTRACT Introduction Cardiorespiratory fitness (CRF) measured by oxygen consumption (V˙O 2 ) during exercise is an important marker of health. The traditional method indexing V˙O to total body mass suboptimal because skeletal muscle (SMM), rather than fat and extracellular fluid, the main contributor CRF. estimating equations for peak in youth do not account this. Bioelectric impedance analysis (BIA) a noninvasive accurately measure composition. objectives this study were 1) examine...
Abstract Background Left ventricular diastolic dysfunction (DD) is an independent risk factor for mortality in sickle cell anemia (SCA) and associated with increased extracellular volume (ECV) on cardiac MRI (CMR). Exercise impairment common SCA, but its causes prognostic value are not well understood. Objective To study the effects of DD ECV cardiopulmonary exercise test (CPET) patients SCA. Methods Results As part a prospective to characterize cardiomyopathy SCA (NCT02410811), 20 children...
The Berlin Heart EXCOR pediatric ventricular assist device (VAD) is approved by the Food and Drug Administration for bridge to cardiac transplantation (BTT) in children. As clinical outcomes of continue be evaluated United States, data on post-transplant survival are needed. UNOS database was used identify patients <18 years old undergoing orthotopic heart (OHT) from June 2004 2014. Patients BTT with were identified. A matched cohort (358) OHT without pretransplant mechanical circulatory...
Abstract Increased extracellular volume (ECV) by CMR is a marker of interstitial myocardial fibrosis and associated with diastolic dysfunction in sickle cell anemia (SCA). Left atrial (LA) stiffness contribute to the development heart failure other settings. We aimed evaluate LA function associations ECV, tricuspid regurgitation jet velocity (TRV) exercise abnormalities SCA. In prospective study, individuals SCA underwent CMR, echocardiography test. ECV was measured using MOLLI sequence....
Cardiomyopathy is a common complication among muscular dystrophy (MD) patients and often results in advanced heart failure premature death. In spite of this, there hesitancy to consider transplantation (HTx). This study describes the HTx outcomes with MD United States.All Network for Organ Sharing database from October 1, 1987, March 31, 2016, were identified. Two patient groups created: cohort (n=81), all other cardiomyopathies, called cardiomyopathy-unmatched (n=41 317). Propensity score...
Abstract: There is a limited supply of adequate donor hearts for cardiac transplantation. The safety using advanced‐age has been debated in adult transplantation but not studied previously pediatric recipients. In this retrospective study, survival 79 heart transplant recipients was reviewed. Pediatric recipient groups were stratified based on age (group 1 > 40 yr, n = 5; group 2 ≤ 74). Survival 267 adolescent (ages 11–17) the United Network Organ Sharing (UNOS) database also Patients...