A5073221997- Psoriasis: Treatment and Pathogenesis
- Glass properties and applications
- Inflammatory Biomarkers in Disease Prognosis
- Toxoplasma gondii Research Studies
- Acne and Rosacea Treatments and Effects
- Quantum optics and atomic interactions
- Chromium effects and bioremediation
- Extracellular vesicles in disease
- Dermatology and Skin Diseases
- Mast cells and histamine
- Platelet Disorders and Treatments
- Mitochondrial Function and Pathology
- Neurological Disease Mechanisms and Treatments
- Allergic Rhinitis and Sensitization
- Metabolism and Genetic Disorders
- Heavy Metals in Plants
- Protein purification and stability
- Metabolomics and Mass Spectrometry Studies
- Cardiovascular Disease and Adiposity
- Optical properties and cooling technologies in crystalline materials
- Neuroinflammation and Neurodegeneration Mechanisms
- Adipokines, Inflammation, and Metabolic Diseases
- Neonatal Respiratory Health Research
- Venous Thromboembolism Diagnosis and Management
- Medical and Biological Ozone Research
Yunnan Agricultural University
2024
Beijing Chao-Yang Hospital
2024
Capital Medical University
2024
Fudan University
2004-2024
Huashan Hospital
2017-2024
Ruijin Hospital
2024
Shanghai Jiao Tong University
2024
Chronic cerebral hypoperfusion (CCH), as a critical factor of chronic cerebrovascular diseases, has greatly influenced the health patients with vascular dementia. Vitexin, flavone C-glycoside (apigenin-8-C-β-D-glucopyranoside) that belongs to subclass flavonoids, been shown possess antioxidant and anti-ischemic properties; however, putative protective effects vitexin on CCH need further investigation. In current study, role its underlying mechanism were investigated permanent bilateral...
BACKGROUND Platelets for transfusion become senescent and dysfunctional during storage, resulting in a markedly short shelf life (5 days). We hypothesized that oxidative stress might account this decline. STUDY DESIGN AND METHODS Human platelets were treated with or without antioxidants before samples collected analyzed at different time points. Platelet senescence was determined by senescence‐associated β‐galactosidase assay, senescence‐related platelet qualities also analyzed. RESULTS Sign...
The optical properties of erbium-doped bismuth-based oxide glasses were studied in this letter. By adding a proper amount hydroxyl group as the deactivator, excited state absorption and upconversion erbium restrained. mechanism is explained some amplifiers with good are produced.
There are great interindividual variations in the clinical efficacy of methotrexate (MTX) treatment and patients' genetic background seems promising its explanation.The study aimed to test whether polymorphism annexin A6 (ANxA6) gene, a susceptibility factor for psoriasis, was associated with response MTX therapy.A total 325 patients enrolled received oral treatment, whom 310 completed 1-year performed genotype analysis. They were defined as responders (a reduction Psoriasis Area Severity...
Background: Increasing numbers of studies reported platelet (PLT)- related measures could play a creative role in many malignancies, while the prognostic impact these hepatocellular carcinoma (HCC) remains limited and controversial. It is worth exploring predictive value PLT-related HCC. Methods: A total 279 HCC patients with hepatectomy were analyzed retrospective cohort study. The optimal cut-off points indices obtained by receiver operating characteristic (ROC) curve. associations...
<b><i>Background:</i></b> The study aimed to investigate the relationship of MAPK4 genetic variants with efficacy methotrexate (MTX) in psoriasis patients. <b><i>Methods:</i></b> Patients treated MTX were classified as responders or nonresponders if Psoriasis Area and Severity Index (PASI) at week 12 was reduced greater than 75% lower 75%, respectively. genotypes 14 single-nucleotide polymorphisms 310 patients analyzed. expression levels...
Psoriasis is a common chronic inflammatory and proliferative skin disease that prone to recurrence, long course, hard cure. Currently, methotrexate (MTX)-based systematic treatment the most widely used regimen for psoriasis in clinical practice. Long-term oral administration of MTX has plethora side effects, including induced liver kidney toxicity even bone marrow suppression severe cases. To reduce incidence adverse reactions, topical application nano-drug delivery systems by modifying...
To the best of our knowledge, association inflammatory parameters with hepatic hydatid disease (HD) has not been investigated in a single study. We aimed to evaluate potential value indices this disorder.The retrospective study including 114 patients was performed from January 2016 November 2019. Clinical characteristics and laboratory data for all participants were collected analysed. The levels compared patient control group, predictive these assessed by logistic regression analysis...
Abstract Purpose: To provide the first insight into proteomic dynamics during platelet storage. Experiment design: In this study, based on TMT-labeled LC-MS/MS analysis, combined with antibody-affinity enrichment and purification for acetylated succinylated peptides, we performed quantification of global proteomics, acetylome succinylome.Simultaneously, dynamic molecular changes functional transformation were also characterized under proper conditions stored 1, 3, 5, 7 days, respectively....