- Cardiac Arrhythmias and Treatments
- Pericarditis and Cardiac Tamponade
- Electrolyte and hormonal disorders
- Viral Infections and Immunology Research
- Eosinophilic Disorders and Syndromes
- Renin-Angiotensin System Studies
- Cardiovascular Function and Risk Factors
- Hormonal Regulation and Hypertension
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Neuroscience of respiration and sleep
- Lipoproteins and Cardiovascular Health
- Birth, Development, and Health
- Cardiac Structural Anomalies and Repair
- Cancer, Lipids, and Metabolism
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Parathyroid Disorders and Treatments
- Human Health and Disease
- Veterinary Medicine and Surgery
- Sleep and Wakefulness Research
- High Altitude and Hypoxia
- Acute Myocardial Infarction Research
- Heart Rate Variability and Autonomic Control
- Ferroptosis and cancer prognosis
- Lymphatic Disorders and Treatments
Nagasaki University Hospital
2025
Nagasaki University
2020-2024
Sasebo City General Hospital
2020-2024
Nagasaki Medical Center
2021-2022
University of California San Francisco Medical Center
1968-1971
Stanford University
1971
Electrodes were implanted in dogs the dorsal portion of medulla oblongata near obex. A week or more later, electrodes stimulated while changes plasma renin activity, epinephrine and norepinephrine, blood pressure monitored. Stimulation 20 points 16 produced clear-cut increases activity. In almost all instances, these associated with marked pressure. There was also a small increase circulating without significant change norepinephrine. 4 h after renal denervation not any activity even though...
Comparisons between the resting full-cycle ratio (RFR), a new physiological index, and fractional flow reserve (FFR) in terms of prognostic value are limited. We aimed to identify concordance RFR FFR determine stability measured RFR.We 161 coronary arteries 119 patients classified data using known cutoffs for (≤0.80) (≤0.89) into groups; high (high FFR/low RFR) group, low (low FFR/high group. The rates these groups were 42.2% (68/161), 4.4% (7/161), 14.3% (23/161), 39.1% (63/161),...
SummaryExogenous dog renin was administered intravenously to nephrectomized dogs and its disappearance followed for 3 hours. There were two exponential components the curves, a rapid component with an average half-time of 6 ± 1 min slower 79 7 min. Circulating angiotensin levels shown have no effect on either value presence adequate substrate demonstrated. The mean plasma level in pentobarbital-anesthetized found be 10.2 1.0 mμg II generated/ml/3 Four hours after nephrectomy, it 1.3 0.2 mμg....
Coronavirus disease 2019 (COVID-19) vaccination is reportedly safe and effective. The histologic features of post-COVID-19 myocarditis are unknown. We present a case 77-year-old Japanese woman diagnosed with eosinophilic using endomyocardial biopsy, 7 days after the second dose BNT162b2 COVID-19 vaccine. Steroid pulse therapy was
A 70-year-old man was admitted to our hospital for restoration of sinus rhythm from atrial fibrillation by direct current counter shocks. On admission, he had a coronavirus disease 2019 (COVID-19) infection and syncope during bed rest. Electrocardiography revealed polymorphic ventricular tachycardia after ST-segment elevation with normal QT interval. Coronary angiography coronary vasospasm. vasospasm may be cause in COVID-19 patients.
SummaryIn pentobarbital-anesthetized normal dogs previously fed a diet providing approximately 40 mEq of sodium per day, hemorrhage caused an increase in circulating renin levels. The values continued to rise 30 and 60 min after when blood pressure was returning toward normal. Plasma levels were very low 4 hours bilateral nephrectomy they failed following the nephrectomized dogs. Dogs for 14 days had higher prehemorrhage much greater plasma than animals day.
Abstract Background The relationship between induction and recurrence due to atrial tachycardia (AT) left (LA) matrix progression after fibrillation (AF) ablation remains unclear. Methods One hundred fifty-two consecutive patients with paroxysmal persistent AF who underwent pulmonary vein isolation (PVI) cavo-tricuspid isthmus (CTI) achieved sinus rhythm before the procedure were classified into three groups according AT pattern induced procedure: group N (non-induced), F (focal pattern), M...
A 74-year-old Japanese man was admitted to our hospital for catheter ablation of paroxysmal atrial fibrillation. Transthoracic echocardiography revealed basal interventricular septal hypertrophy without apical sparing. Cardiac magnetic resonance imaging late gadolinium enhancement in the hypertrophic lesions. The Kumamoto criteria one point, and patient had no carpal tunnel syndrome. However, technetium-99m pyrophosphate scintigraphy an accumulation region left ventricle. skin biopsy...
The importance of treating non-pulmonary vein (PV) foci is increasing with improvements in the durability PV isolation. We describe two cases wherein non-PV were induced by mechanical irritation and conventional induction same area, which was impossible to induce after ablation, suggesting a relationship between foci. In recurrent case foci, atrial fibrillation (AF) only irritation. No recurrence has been observed since ablation area. Thus, treatment AF site could be considered an effective...
Atrial fibrillation (AF) is a common arrhythmia associated with cardiac amyloidosis (CA). Diastolic dysfunction and atrial lesions have been reported in patients AF fibrillation. We aimed to evaluate the diastolic function CA AF.
The 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, also known as statins, are administered first-line therapy for hypercholesterolemia, both primary and secondary prevention. Besides the lipid-lowering effect, statins have been suggested to inhibit development of cardiovascular disease through anti-inflammatory, antioxidant, vascular endothelial function-improving, plaque-stabilizing, platelet aggregation-inhibiting effects. preventive effect on atherothrombotic stroke...
Extracellular single-unit recordings were made from medial preoptic/anterior hypothalamic (MPOAH) neurones in urethane-anaesthetized female rats, and the responses of these to electrical stimulation ventrolateral medulla (VLM) investigated. Of 189 tested, 20% excited 21% inhibited following VLM stimulation. The latency inhibitory showed a normal distribution mean was 47 ms, whereas excitatory bimodal with peaks ranges 0-10 ms 40-50 respectively. Excitatory latencies greater than 15...
Abstract Background The importance of left ventricle diastolic dysfunction (LVDD) has been recognized widely, as it is well established that heart failure with preserved ejection fraction a poor prognosis. Furthermore, N-terminal pro–B-type natriuretic peptide (NT-ProBNP) used marker failure. However, the association between LVDD and NT-proBNP unclear. Purpose aim this study was to clarify NT-ProBNP. Methods In study, an index based on gated myocardial perfusion SPECT using CardioREPO...
Coronavirus disease 2019 (COVID-19) vaccination is reportedly safe and effective. The histologic features of post-COVID-19 myocarditis are unknown. We present a 77-year-old Japanese woman who was diagnosed with eosinophilic using endomyocardial biopsy, 7 days after receiving the second dose BNT162b2 COVID-19 vaccine. Methylprednisolone pulse therapy