A5010167438- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Cardiac tumors and thrombi
- Central Venous Catheters and Hemodialysis
- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Cardiovascular Disease and Adiposity
- Parathyroid Disorders and Treatments
- Cardiac Arrhythmias and Treatments
- Cardiovascular Health and Disease Prevention
- Long-Term Effects of COVID-19
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Biomarkers in Disease Mechanisms
- Coronary Artery Anomalies
- Diet and metabolism studies
- Aortic Thrombus and Embolism
- Vascular Anomalies and Treatments
- Peripheral Artery Disease Management
Nagasaki University
2016-2025
Nagasaki University Hospital
2014-2025
Toho University
2024
Toho University Ohashi Medical Center
2024
Foundation of Cardiac Surgery Development
2022
Rigaku (Japan)
2021
Hokkaido University
2020
Yamaguchi University Hospital
2020
Kumamoto University
2019
Kanazawa University
2019
Low back pain (LBP) is the most common cause of chronic pain. Numerous clinical scales are available for evaluating pain, but their objective criteria in management LBP patients remain unclear. This study aimed to determine an cutoff value a change Pain Intensity Numerical Rating Scale (ΔPI-NRS) three months after treatment. Its utility was compared with changes six commonly used patients: Disability Assessment (PDAS), Self-Efficacy Questionnaire (PSEC), Catastrophizing (PCS), Athens...
BACKGROUND: The optimal duration of anticoagulation therapy for isolated distal deep vein thrombosis in patients with cancer is clinically relevant, but the evidence lacking. prolonged could have a potential benefit prevention thrombotic events; however, it also increase risk bleeding. METHODS: In multicenter, open-label, adjudicator-blinded, randomized clinical trial at 60 institutions Japan, we randomly assigned thrombosis, 1-to-1 ratio, to receive either 12-month or 3-month edoxaban...
There has been limited data on anticoagulation strategies and long-term recurrence in patients with venous thromboembolism (VTE) the era of direct oral anticoagulant (DOAC).The COMMAND VTE Registry-2 is a multicenter retrospective cohort study enrolling 5197 consecutive acute symptomatic between January 2015 August 2020 among 31 centers Japan. In this primary report, entire was divided into 5 groups; major transient risk factors (N = 475, 9.1%), minor 788, 15%), unprovoked 1913, 37%),...
Abstract There is no standard treatment for peritoneal carcinomatosis (PC) from gastric cancer. New bidirectional chemotherapy (neoadjuvant intraperitoneal‐systemic protocol (NIPS)) was developed. The aim of the present study to assess safety and efficacy NIPS show selection cytoreductive surgery on PC Seventy‐nine patients with cancer were treated NIPS. A port system introduced into abdominal cavity. wash cytological examination through a done before after oral TS‐1 twice daily 21 days,...
Electrocardiographic abnormalities, cardiac injury, and autonomic nervous function were investigated in patients with acute-phase subarachnoid hemorrhage (SAH) (42 SAH related to ruptured aneurysm 42 control subjects). Electrocardiogram Holter electrocardiogram for spectral analysis of heart rate variability (HRV) recorded. Concentrations cardiogenic enzymes (ie, creatine kinase-myocardial fraction [CK-MB], myosin light chain I, troponin T), plasma concentrations catecholamine noradrenaline,...
BackgroundData on thrombosis and current real-world management strategies for anticoagulation therapy are scarce but important understanding issues unmet needs of an optimal patients with coronavirus disease 2019 (COVID-19).MethodThe CLOT-COVID Study (thrombosis antiCoaguLatiOn Therapy in COVID-19 Japan Study: UMIN000045800) was a retrospective, multicenter cohort study enrolling consecutive hospitalized among 16 centers from April 2021 to September 2021, we tried capture the status fourth...
Previous studies have shown a possible role for obstructive sleep apnea syndrome (OSAS) in the development and/or progression of chronic kidney disease (CKD). However, impact treatment OSAS on CKD has not been clarified. The aim this study was to investigate influence and short-term effects nasal continuous positive airway pressure (CPAP) estimated glomerular filtration rate (eGFR).We evaluated 38 men with diagnosed polysomnography. associations between eGFR patient characteristics,...
An inflammatory response is a key event for endothelial dysfunction. Pentraxin 3 (PTX3) an protein produced at inflammation sites such as leukocytes and vascular cells. Here, we compared the relationships between function assessed by flow-mediated dilation (FMD), levels of plasma PTX3 high-sensitive C-reactive (hsCRP), another pentraxin family. Levels FMD, hsCRP were measured twice within 6 to 8 months retrospectively analyzed in 36 patients with coronary artery disease. We examined...
The contemporary outcome of balloon pulmonary angioplasty (BPA) and endarterectomy (PEA) in patients with chronic thromboembolic hypertension (CTEPH) are unclear.
The risk of recurrent venous thromboembolism (VTE) in patients with isolated distal deep vein thrombosis (IDDVT) is generally low, particularly when IDDVT asymptomatic. However, cancer IDDVT, even asymptomatic may be at a higher VTE. To compare the clinical outcomes and symptomatic IDDVT. ONCO DVT trial randomized that compared 12-month versus 3-month edoxaban treatment regimens In this post hoc analysis, 601 were categorized into (n = 479) 122) groups based on IDDVT-related symptoms...
Background Real-world data on clinical characteristics and outcomes related to the use of different direct oral anticoagulants (DOACs) for cancer-associated venous thromboembolism (VTE) is lacking. Methods The COMMAND VTE Registry-2 a multicenter registry enrolling 5,197 consecutive patients with acute symptomatic from 31 centers in Japan January 2015 August 2020. Our study population comprised 1,197 active cancer who were divided into edoxaban (N = 643, 54%), rivaroxaban 297, 25%), apixaban...
Coronavirus disease 2019 (COVID-19) reportedly causes venous thromboembolism (VTE), but the status of this complication in Japan was unclear.
The coronavirus disease 2019 (COVID-19) causes extensive coagulopathy and a potential benefit of anticoagulation therapy has been documented for prevention thromboembolic events. Bleeding events also reported as notable complication; whereas, the incidence, risks, clinical impact bleeding remain unclear.The CLOT-COVID Study was nationwide, retrospective, multicenter cohort study on consecutive hospitalized patients with COVID-19 in Japan between April 2021 September 2021. In this...