A5035389089- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Radioactive contamination and transfer
- Cardiac Imaging and Diagnostics
- Radiation Dose and Imaging
- Radioactivity and Radon Measurements
- Medical Imaging and Pathology Studies
- Risk Perception and Management
- Radiopharmaceutical Chemistry and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiovascular Function and Risk Factors
- Effects of Radiation Exposure
- Cancer, Hypoxia, and Metabolism
- Radiomics and Machine Learning in Medical Imaging
- Mitochondrial Function and Pathology
- Liver Disease Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- COVID-19 and healthcare impacts
- Cerebrovascular and Carotid Artery Diseases
- Thyroid Cancer Diagnosis and Treatment
- Lanthanide and Transition Metal Complexes
- DNA Repair Mechanisms
- Advanced X-ray and CT Imaging
- Cardiomyopathy and Myosin Studies
Nagasaki University
2016-2025
Fukuoka Tokushukai Hospital
2011-2024
Yamagata Prefectural Central Hospital
2021-2024
Nagasaki University Hospital
2017-2024
Education Development Center
2024
Sendai Shakai Hoken Hospital
2016-2019
University of North Carolina at Chapel Hill
2017
North Carolina State University
2017
First Affiliated Hospital of Zhengzhou University
2017
Kindai University
2002-2013
Rationale: Stem cell therapy faces several challenges. It is difficult to grow, preserve, and transport stem cells before they are administered the patient. Synthetic analogs for represent a new approach overcome these hurdles hold potential revolutionize regenerative medicine. Objective: We aim fabricate synthetic of test their therapeutic treatment acute myocardial infarction in mice. Methods Results: packaged secreted factors from human bone marrow–derived mesenchymal (MSC) into...
The coronavirus disease 2019 (COVID-19) pandemic has adversely affected diagnosis and treatment of noncommunicable diseases. Its effects on delivery diagnostic care for cardiovascular disease, which remains the leading cause death worldwide, have not been quantified.The study sought to assess COVID-19's impact global procedural volumes safety practices.The International Atomic Energy Agency conducted a worldwide survey assessing alterations in procedure practices resulting from COVID-19....
Understanding tumor-specific metabolism under hypoxia is important to find novel targets for antitumor drug design. Here we found that tumor cells expressed higher levels of cytosolic acetyl-CoA synthetase (ACSS2) than normoxia. Knockdown ACSS2 by RNA interference (RNAi) in enhanced cell death long-term vitro. Our data also demonstrated the suppression slowed growth vivo. These findings showed plays a significant role survival and would be potential target treatment. Furthermore, excreted...
Information on early internal radiation doses in Fukushima after the nuclear power plant accident March 11, 2011, is quite limited due to initial organizational difficulties, high background and contamination of measuring devices. In Nagasaki, approximately 1,200 km away from Fukushima, radioactivity evacuees short-term visitors has been measured by a whole body counter (WBC) since 15, 2011. A horizontal bed-type scanning WBC equipped with two NaI(Tl) scintillation detectors was used for 173...
Artificial neural networks (ANN) might help to diagnose coronary artery disease. This study aimed determine whether the diagnostic accuracy of an ANN-based system and conventional quantitation are comparable.
The extent to which health care systems have adapted the COVID-19 pandemic provide necessary cardiac diagnostic services is unknown. aim of this study was determine impact on testing practices, volumes and types services, perceived psychological stress providers worldwide. International Atomic Energy Agency conducted a worldwide survey assessing alterations from baseline in cardiovascular at pandemic's onset 1 year later. Multivariable regression used factors associated with procedure volume...
The purpose of this study was to delineate the differences in intratumoral uptake and tracer distribution <sup>62</sup>Cu-diacetyl-bis(<i>N</i><sup>4</sup>-methylthiosemicarbazone) (<sup>62</sup>Cu-ATSM), a well-known hypoxic imaging tracer, <sup>18</sup>F-FDG patients with lung cancer pathohistologically different types. <b>Methods:</b> Eight squamous cell carcinoma (SCC) 5 adenocarcinoma underwent <sup>62</sup>Cu-ATSM PET within 1-wk interval. For PET, 10-min static data acquisition...
The grade of histologic differentiation is one the most important prognostic factors in patients with endometrial carcinoma and postoperative staging. aim this study was to investigate whether 16α-<sup>18</sup>F-fluoro-17β-estradiol (<sup>18</sup>F-FES) <sup>18</sup>F-FDG PET reflect clinicopathologic features tumors. <b>Methods:</b> A total 22 adenocarcinoma 9 hyperplasia (mean age, 56.0 ± 15.3 y) underwent <sup>18</sup>F-FES for estrogen receptor imaging PET. Regional values tracer uptake...
A 65-year-old woman was admitted to our hospital with heart failure secondary aortic regurgitation and paroxysmal atrial fibrillation. During surgery for valve-sparing root replacement, a biopsy obtained from the right atrium because of AF mild LV hypokinesis. histopathological examination revealed natriuretic peptide amyloidosis, patient clinically diagnosed isolated amyloidosis (IAA). Although IAA is rarely clinically, it should be considered in patients failure.
Introduction Mycobacterium avium complex pulmonary disease (MAC-PD) necessitates prolonged treatment. However, determining the appropriate time to conclude treatment is challenging because of lack indices for evaluating activity. Fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) can be used visualize inflammatory sites and hypothesized indicate efficacy in diseases. Therefore, we conducted this single-arm, open-label, interventional study investigate utility...
Background A longitudinal, base-to-apex myocardial perfusion gradient has been described in patients with coronary artery disease (CAD) and was attributed to diffuse luminal narrowing. We asked whether an abnormal also existed without CAD but risk factors. measured blood flow (MBF) 13 N-ammonia PET at rest during hyperemia factors CAD. Methods Results Regional MBF absolute units dipyridamole 36 (age, 55±10 years) age-matched 53±10 28 young 25±5 normal subjects. determined globally, for each...
Background — We explored the feasibility of measuring regional tracer activity concentrations and flow defects in myocardium rats with a high spatial resolution small-animal PET system (microPET). Methods Results Myocardial images were obtained after intravenous 18 F-fluorodeoxyglucose ( FDG) 11 normal (group 1) assembled into polar maps. Regional F measured 9 regions interest compared tissue by well counting. In another 2), myocardial perfusion acquired 13 N -ammonia at baseline during...
Since the accident at Chernobyl Nuclear Power Plant, it has become well known that radiocesium tends to concentrate in wild mushrooms. During recovery process after Fukushima Daiichi Station (FDNPS), is important perform follow-up measurements of activity concentrations We evaluated detected artificial radionuclides (radiocesium) mushrooms collected from Kawauchi village, which within 30 km FDNPS, 2015, four years accident. found was determined 147 159 mushroom samples (92.4%). Based on...
The prognosis and treatment of thyroid cancer depends on the type stage disease. Radiosensitivity differs among cells owing to their varying capacity for repair after irradiation. Radioactive iodine can be used destroy cells. However, patient improvement irradiation varies. Therefore, predictive measures are important avoiding unnecessary exposure radiation. We describe a new method predicting effects radiation in individual cases based DNA-dependent protein kinase (DNA-PK) activity level...
The aim of our study was to identify the factors associated with intention return (ITR) in residents Tomioka town, Fukushima Prefecture. We contacted approximated 8000 aged 20 years or older who lived Tomioka. invited them take part a written survey on ITR. In all, 1749 residents' replies were included analysis. asked about ITR former town. also relevant and risk perception relation health effects radiation exposure. Of those contacted, 469 (26.8%) had an Logistic regression analysis...