A5101915945- Nutrition and Health in Aging
- Cancer, Hypoxia, and Metabolism
- Nutritional Studies and Diet
- Immune cells in cancer
- Phytochemicals and Antioxidant Activities
- Cancer, Lipids, and Metabolism
- Skin Protection and Aging
- Cancer Treatment and Pharmacology
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Cells and Metastasis
- Flavonoids in Medical Research
- Head and Neck Cancer Studies
- Papaya Research and Applications
- Cancer survivorship and care
- Phytochemical and Pharmacological Studies
- Natural Antidiabetic Agents Studies
- Cytokine Signaling Pathways and Interactions
- Ginseng Biological Effects and Applications
- Hydraulic and Pneumatic Systems
- Radiation Therapy and Dosimetry
- Management of metastatic bone disease
- Bladder and Urothelial Cancer Treatments
- Chemotherapy-induced organ toxicity mitigation
- Chemokine receptors and signaling
- Advanced Chemical Sensor Technologies
Agricultural Technology Research Institute
2022-2024
National Taiwan Ocean University
2007-2024
Chang Gung University
2011-2024
Keelung Chang Gung Memorial Hospital
2014-2024
Chang Gung Memorial Hospital
2016-2022
Linkou Chang Gung Memorial Hospital
2011
Memorial Hospital of South Bend
2011
Dayeh University
2007
National Yunlin University of Science and Technology
2007
Abstract The correlations of pretreatment serum concentrations proinflammatory cytokines such as interleukin (IL)‐1 β , IL‐6, and tumor necrosis factor‐ α (TNF ) with the clinicopathologic features progression colorectal cancer (CRC) were investigated. levels IL‐1 TNF measured in 164 CRC patients before treatment. relationships between changes cytokine C‐reactive protein (CRP) both variables disease examined by univariate multivariate analysis. Advanced stage was associated a poorer...
Abstract Background The aim of this study was to determine the effect tumor encapsulation hepatocellular carcinoma (HCC) on long‐term survival. Methods A retrospective review 1,240 patients who underwent hepatectomy from January 1993 June 2005 conducted. There were 891 with (EC type) and 349 without (NC type). Clinicopathological factors, surgical outcome, survival analyzed. Results Disease‐free (DFS) affected by margin involvement, presence complications, vascular invasion, liver cirrhosis,...
Lung cancer and its related cachexia are the leading cause of death in world. In this study, we report inhibitory effect combined therapy Astragalus membranaceus Angelica sinensis, on tumor growth tumor-bearing mice. Lewis lung carcinoma cells were inoculated into male C57BL/6 CAnN.Cg-Foxn1nu nude After inoculation, mice fed orally by combination AM AS different doses. mice, significantly inhibited prevented loss body weight skeletal muscle. It also diminished formation free radicals...
This study aimed to evaluate the effect of Astragalus polysaccharides (PG2) on reducing chemotherapy-induced fatigue (CIF) and toxicity, thereby encouraging compliance chemotherapy. was a randomized, placebo-controlled, phase 2 study. Patients with stage II/III early breast cancer planning undergo adjuvant anthracycline-based chemotherapy were randomly assigned receive PG2 500 mg or placebo days 1, 3, 8 every 21 days. The global score (FGS) assessed using brief inventory (BFI)-Taiwan. Breast...
This study was designed to evaluate the impact of prognostic nutritional index (PNI) on treatment-related toxicities and tolerance in patients with advanced head neck cancers who were undergoing concurrent chemoradiotherapy (CCRT).We retrospectively analyzed compared clinical characteristic, survival 143 stage III, IVA, IVB cancer treated CCRT according their PNI between 2007 2010.Low correlated T classification tumor stage. Patients low less likely tolerate CCRT, required tube feeding...
Nowadays, the active suspension is key technology for vehicles to achieve both ride comfort and control performance. In this paper, a new 1/4T servo-hydraulic vehicle system developed two schemes are utilized. The first one conventional PID controller obtained from Ziegler-Nichols method second neural network controller. Though these controllers quite simple not new, it still worth mentioning that paper emphasizes on engineering aspects including design of test rig, implementation subsequent...
Study on the impact of pretreatment malnutrition treatment outcomes in locally advanced head and neck cancer (LAHNC) patients is still lacking. We prospectively collected various assessment methods including nutrition indexes, inflammatory biomarkers, lean body mass index (LBMI) data before treatments. The one year mortality rate was assessed, factors associated with this outcome were investigated. Furthermore, association between examined. A total 113 enrolled. By prognostic stratification...
Background: Aristolochic acids (AAs) are potent mutagens commonly found in herbal plant-based remedies widely used throughout Asian countries. Patients and Methods: To understand whether AA is involved the tumorigenesis of oro-gastrointestinal tract, we whole-exome sequencing to profile 54 cases four distinct types tract cancer (OGITC) from Taiwan. Results: A diverse landscape mutational signatures including those DNA mismatch repair reactive oxygen species was observed. APOBEC were observed...
Alopecia is one of the most common adverse effects chemotherapy. It reduces patient's self-esteem and quality life effect therapy. Scalp cooling only verified current method for prevention but success not guaranteed, particularly after receiving anthracycline-based combinations. Low-level light therapy has been clinically proven to inhibit progress androgenic alopecia. A previous study using human subjects shows limited benefits low-level patients who suffer chemotherapy-induced alopecia an...
Despite the effectiveness of primary treatment modalities for cancer, side effects treatments, medication resistance, and deterioration cachexia after disease progression lead to poor prognosis. A supportive modality overcome these limitations would be considered a major breakthrough. Here, we used two different target drugs demonstrate whether nutraceutical formula (fish oil, Se yeast, micronutrient-enriched nutrition; NuF) can interfere with cancer improve drug efficacy. After Lewis lung...
Non-small-cell lung cancer (NSCLC) causes high mortality. Radiotherapy is an induction regimen generally applied to patients with NSCLC. In view of therapeutic efficacy, the outcome not appealing in addition bringing about unwanted side effects. Total nutrition a new trend therapy, which benefits under radiotherapy. Male C57BL/6JNarl mice were experimentally divided into five groups: one control group, T group (borne Lewis carcinoma but no treatment), and three carcinoma-bearing groups...
Abstract Over 0.4 billion people consume Chinese white salted noodles (CWSN) as their daily main diet. Rapid flavour and taste control of CWSN has consequently attracted much attention from noodle processors distributors. In this study, the conventional solid‐phase microextraction (SPME) technique plus GC GC–MS was used to concentrate odorants in examine its potential for improving related quality (QC) technology. The results indicated that optimum adsorption time temperature are 160 min 30...
(1) Background: Radiotherapy (RT) is one of the major treatments for non-small cell lung cancer, but RT-associated toxicities usually impede its anticancer effect. Nutrient supplementation has been applied cancer prevention or a complementary measure to therapy. Here, we explored influence total nutrition before and after occurrence on benefit side effects RT. (2) Methods: C57BL/6JNarl mice were inoculated with Lewis carcinoma cells then treated radiotherapy. TNuF, formula, was prescribed by...
In recent years, various factors such as shifts in health consciousness, changes lifestyle habits, increased focus on dietary intake, the promotion of alternative medical concepts, and advancements life sciences technology have propelled robust growth food industry. An increasing number reports suggest that "functional foods," containing beneficial functional components, may enhance short-term well-being are increasingly regarded healthful. Building upon these findings, this study aims to...
<title>Abstract</title> <bold>Purpose</bold> This study aimed to evaluate the effect of <italic>Astragalus</italic> polysaccharides (PG2) on reducing chemotherapy-induced fatigue (CIF) and toxicity, thereby encouraging compliance chemotherapy. <bold>Methods</bold> was a randomized, placebo-controlled, phase 2 study. Patients with stage II/III early breast cancer planning undergo adjuvant anthracycline-based chemotherapy were randomly assigned receive PG2 500 mg or placebo days 1, 3, 8 every...
Papaya (Carica papaya L.) is a rich-nutrition fruit include vitamins (A, B and C), carbohydrates, proteins, alkaloids, proteolytic enzymes, benzyl isothiocyanate. contains papain, which helps strengthen the constitution of diabetes patients. Its water-soluble fiber can stabilize blood sugar levels, reducing risk complications. has benefits such as lowering lipids softening vessels due to acids it contains, advantageous for patients with complicated by hypertension, arteriosclerosis,...
Lung cancer and cachexia are the leading causes of cancer-related deaths worldwide. Cachexia is manifested by weight loss white adipose tissue (WAT) atrophy. Limited nutritional supplements conducive to lung patients, whereas underlying mechanisms poorly understood. In this study, we used a murine model investigate effects formula (NuF) rich in fish oil selenium yeast as an adjuvant enhance drug efficacy EGFR inhibitor (Tarceva). contrast healthy control, tumor-bearing mice exhibited severe...
Platostoma palustre (Pp) jelly is a traditional food. Pp has been used as folk medicine and effective against heat-shock, hypertension diabetes. Therefore, the aim of this study was to evaluate ethanolic extracts Pp’ genotoxicity. The by using 40% ethanol for extraction. Evaluation genotoxicity micronucleus assay performed in vivo. During vivo genotoxicity-evaluated experiment, experimental animal’s clinical behavior, body weight (BW), food consumption, percentage RET/RBCs (reticulocytes/red...
e18041 Background: PEP503 (aka NBTXR3), a novel radioenhancer composed of functionalized hafnium oxide nanoparticles, is designed for intratumoral injection to increase radiation energy deposition within solid tumors and subsequent tumor cell killing, without increasing toxicity surrounding healthy tissue. nanoparticles plus RT has been tested in elderly HNSCC patients demonstrated good safety profile. The phase 1b part the study aimed test feasibility recommended 2 dose (RP2D) when added...
Platostoma palustre jelly is a traditional food. has been used as folk medicine and effective against heat-shock, hypertension diabetes. Therefore, the aim of this study was to determine effects ethanolic extracts commercial herbal tea in inhibiting colorectal cancer cell viability. The by using 90% ethanol for extraction. In study, 2-fold serial dilution 100 mg/mL were applied. On other hand, same fold also performed 100% with palustre. Additionally, CT-26 HT-29 lines study. After...