A5100613982- Cardiac Fibrosis and Remodeling
- Occupational Health and Safety Research
- Antibiotics Pharmacokinetics and Efficacy
- Food Security and Health in Diverse Populations
- Lung Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Maternal Mental Health During Pregnancy and Postpartum
- Veterinary Pharmacology and Anesthesia
- Effects of Radiation Exposure
- Viral Infections and Immunology Research
- Medical Imaging Techniques and Applications
- Antifungal resistance and susceptibility
- Maritime Navigation and Safety
- Signaling Pathways in Disease
- Gestational Diabetes Research and Management
- Cancer, Hypoxia, and Metabolism
- Drug-Induced Hepatotoxicity and Protection
- Urban Agriculture and Sustainability
- Traumatic Ocular and Foreign Body Injuries
- Osteoarthritis Treatment and Mechanisms
- Phenothiazines and Benzothiazines Synthesis and Activities
- Forensic and Genetic Research
- Infrastructure Resilience and Vulnerability Analysis
- Fungal Biology and Applications
- Ocular and Laser Science Research
Nankai University
2024-2025
Beijing Jiaotong University
2024
New York University Shanghai
2022-2024
Center for Global Health
2023
Fudan University
2022
Zhongshan Hospital
2022
Hunan Normal University
2022
Hunan Provincial People's Hospital
2022
Mengchao Hepatobiliary Hospital
2022
Fujian Medical University
2022
We present here a combined GC–MS and LC–MS metabolic profiling approach to unraveling the pathological outcomes of aristolochic acid (AA)‐induced nephrotoxicity. Urine samples were analyzed by in combination with pattern recognition techniques, e.g. principal component analysis (PCA), orthogonal projection latent structure‐discriminant analysis. The work indicates that AA‐induced acute renal toxicity as evidenced histopathological examinations could be characterized systemic disturbance...
Abstract Background Cardiac fibrosis is significant global health problem, which associated with numerous cardiovascular diseases, and ultimately leads to the progression heart failure. β-adrenergic receptor (β-AR) overactivation play a role in development of cardiac fibrosis. Miglustat (Mig) has shown anti-fibrosis effects multiple fibrotic diseases. However, it unclear whether how Mig can ameliorate induced by β-AR overactivation. Methods In vivo, mice were injected isoproterenol (ISO)...
Skin fibrosis including keloids, which are characterized excessive deposition, abnormal proliferation, aggressiveness, and migration of the extracellular matrix dermal fibroblasts. TGF-β signaling is a classical pro-fibrotic pathway, it plays crucial part in occurrence progression skin fibrosis. Daidzein (Dai), an isoflavone compound, has been proved to possess anti-fibrosis effect by various inflammatory fibrotic diseases. However, little known about Dai on Therefore, we further explored...
The SARS-CoV-2 coronavirus pandemic has led to increased food insecurity levels. This cross-sectional study examines the prevalence and determinants of during two-month (1 April 1 June 2022) city-wide lockdown in Shanghai. data was collected via an online questionnaire from 3230 adult Shanghai residents lockdown. Food measured using adapted version Household Insecurity Access Scale. Nearly 70% participants reported being exposed insecurity. Using multivariable logistic regressions, we...
Cimetidine, an antagonist of histamine type II receptors, has shown protective effects against γ-rays or neutrons. However, there have been no reports on the cimetidine neutrons combined with γ-rays. This study was carried out to evaluate rats exposed long-term, low-dose-rate neutron and γ-ray irradiation (n-γ LDR). Fifty male Sprague-Dawley (SD) were randomly divided into 5 groups: normal control group, radiation model 20 mg/(kg · d) 80 group 160 (10 per group). Except for 40 simultaneously...
Severe mechanical ocular trauma with no light perception (NLP) predicts a poor prognosis of visual acuity and enucleation the eyeball. Since innovative treatment concept exploratory vitreoretinal surgery has developed technology advanced, outcomes severe in NLP patients have greatly improved. However, there remains lack unified standards for determination, surgical indication, timing vitrectomy eye treatment. To address these problems, we aimed to create evidence-based medical guidelines...
Abstract Objectives To investigate the sleep quality of women pregnant with a second child and influencing factors provide scientific basis for health care guidance to clinically improve women. Methods A total 162 at first-class tertiary hospital in Changsha from January August 2018 were selected as research subjects. General demographic characteristics collected, Pittsburgh Sleep Quality Index (PSQI) scale was used assess their quality. Multivariate logistic regression analysis explore...
Abstract: A 52-year-old woman was diagnosed with left parietal glioblastoma, and underwent craniotomy near total tumor removal on October 11th, 2017. After the surgery, she received concurrent chemoradiotherapy (6,000 cGy in 30 fractions daily oral temozolomide) adjuvant monthly temozolomide for following 12 months. However, relapse noted during February 2018 by magnetic resonance imaging (MRI) examination. The progressed rapidly, patient experienced right limbs hemiplegia. Therefore,...
Objective: To investigate the psychological status of women during their second pregnancy.Methods: A total 162 who were pregnant for time selected as research subjects.The general demographic data and pregnancy-related conditions subjects investigated by a questionnaire developed this study.The anxiety depression evaluated with self-rating scale (SAS) (SDS). Results:The scored themselves on SAS SDS.There was statistically significant difference when comparing scores domestic norm.Statistical...
This study aimed to investigate the epidemiology and etiological spectrums of BSI in Fujian over past 6 years post antiretroviral treatment (ART) era.A retrospective, observational was conducted include positive inpatients with HIV between September 2015 August 2021 Mengchao Hepatobiliary Hospital Medical University, largest designated HIV/AIDS care hospital Fujian, China. Demographic data laboratory including gender, age, blood cell counts, biochemistry results, CD4 CD8 HIV-RNA loads,...
(1) Background: Radiotherapy (RT) is one of the major treatments for non-small cell lung cancer, but RT-associated toxicities usually impede its anticancer effect. Nutrient supplementation has been applied cancer prevention or a complementary measure to therapy. Here, we explored influence total nutrition before and after occurrence on benefit side effects RT. (2) Methods: C57BL/6JNarl mice were inoculated with Lewis carcinoma cells then treated radiotherapy. TNuF, formula, was prescribed by...
Food insecurity, a pervasive global issue exacerbated by the COVID-19 pandemic, has been linked to adverse mental health outcomes. However, role of social capital in mitigating this relationship remains understudied, particularly Chinese context.
Purpose Construction safety resilience is gradually gaining attention in the field of engineering construction as a new management concept and way to improve performance. However, how cope with dilemma unclear relationship elements at practice level promote harmonization goals enhancement paths has become an urgent challenge for safe construction. Design/methodology/approach This study analyzes components elements. A network model developed by using social analysis method. The location...
β-Adrenergic receptor (β-AR) overactivation is a major pathological factor associated with numerous cardiovascular diseases and mediates cardiac fibrosis. Miglustat (Mig) has shown anti-fibrosis effects in multiple fibrotic diseases. However, it unclear whether how Mig can ameliorate fibrosis induced by β-AR overactivation. Isoproterenol (ISO), nonselective agonist, was chosen to modulate chronic sympathetic activation. In our study, mice were treated or without ISO pretreatment. The results...
The purposes of this study were to establish a unilateral ureteral obstruction renal fibrosis model and determine the pathological changes in interstitial. Expression matrix metalloproteinase-2 tissue inhibitor after tetramethylpyrazine treatments determined.Thirty-two female Sprague Dawley rats randomly divided into 4 groups: sham group, group valsartan group. operated with left ureter ligation model. Rats given intragastric administration 1 day before surgery. tissues examined by...
Facing human's destruction to ecological environment and protruding resource crisis, the anomalous mode of production consumption challenges human survival development brought by population growth??the concept sustainable is put on agendas countries around world. This common strategy shared all correctly handle coordinate interactions society with population, resources, environment, economy, ecology. It's also necessary for development.