Shiyuan Zhang

ORCID: 0000-0001-8523-0419
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About
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Research Areas
  • Asthma and respiratory diseases
  • Respiratory and Cough-Related Research
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Eosinophilic Disorders and Syndromes
  • Chronic Myeloid Leukemia Treatments
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • IL-33, ST2, and ILC Pathways
  • Inhalation and Respiratory Drug Delivery
  • Health and Wellbeing Research
  • Eosinophilic Esophagitis
  • Allergic Rhinitis and Sensitization
  • Hemoglobinopathies and Related Disorders
  • Delphi Technique in Research
  • Kruppel-like factors research
  • Advancements in Battery Materials
  • Computational Geometry and Mesh Generation
  • Optimization and Packing Problems
  • Health Promotion and Cardiovascular Prevention
  • Advanced Battery Materials and Technologies
  • Health, psychology, and well-being
  • Behavioral Health and Interventions
  • Water Quality Monitoring Technologies
  • Identification and Quantification in Food
  • Advanced Battery Technologies Research
  • Diatoms and Algae Research

GlaxoSmithKline (United States)
2023-2025

Shantou University
2024

Soochow University
2024

Northeast Normal University
2024

Providence College
2023

Adelphi Group (United Kingdom)
2023

South College
2022

Abstract Solid‐state lithium metal batteries incorporating LiNi x Co y Mn z O 2 (NCM) as cathodes are developed to meet the high‐energy‐density requirements of energy storage systems. Nevertheless, process plating and stripping Li‐ions on electrodes causes significant volume changes, in which ultimately degrade battery performance. In this study, an elastomeric electrolyte with special latitude‐longitude interwoven structure is designed synthesized successfully, composed a crosslinked phase...

10.1002/aenm.202402040 article EN Advanced Energy Materials 2024-07-11

Abstract Inhaled corticosteroids (ICS) plus long-acting β 2 -agonists (LABA) are recommended for maintenance-only or maintenance and reliever therapy (MART) in patients with asthma. However, real-world data on ICS/LABA as MART limited. This study characterized clinical, economic, humanistic burdens of asthma Canada, China, Europe, Japan, the US, using collected from physicians via a cross-sectional survey (Asthma Disease Specific Programme). Patients were ≥18 years age physician-confirmed...

10.1038/s41533-024-00402-w article EN cc-by npj Primary Care Respiratory Medicine 2025-02-26

Anemia affects many patients with myelofibrosis and is associated poor prognosis. The Janus kinase inhibitor ruxolitinib often used in but may cause or worsen anemia. Using healthcare claims data from the IQVIA PharMetrics Plus database, this retrospective analysis evaluated resource utilization (HCRU), costs, treatment patterns ruxolitinib-treated stratified by anemia diagnosis prior to initiation. Of 11,499 diagnosed between January 2011 December 2022, 481 had ≥ 1 claim on after date were...

10.1007/s00277-025-06279-0 article EN cc-by-nc-nd Annals of Hematology 2025-03-12

Abstract Background There is a need for real-world data describing the frequency and impact of moderate asthma exacerbations in patients receiving inhaled corticosteroids/long-acting β 2 -agonists (ICS/LABA). The Salford Lung Study (SLS) associated extension study (Ext-SLS) evaluated ICS/LABA versus existing maintenance therapy adults with asthma. This analysis assessed from Ext-SLS. Methods retrospective cohort analysed linked primary secondary care patient questionnaire enrolled Ext-SLS...

10.1186/s12931-025-03199-5 article EN cc-by Respiratory Research 2025-03-29

There is limited information regarding multidimensional relationships between asthma control and health-related quality of life (HRQoL), work productivity, symptom burden in Japan. Furthermore, systematic qualitative investigations about have not been performed. This cross-sectional, mixed-methods study included Japanese patients (≥ 20 years) with adherent to inhaled corticosteroids/long-acting β2-agonists (ICS/LABA). The primary endpoint was impact on HRQoL, measured using the Asthma Health...

10.1007/s12325-023-02660-5 article EN cc-by-nc Advances in Therapy 2023-09-12

Abstract This observational claims-linked survey study assessed the prevalence of and risk factors for suboptimal asthma control healthcare utilization in adults with receiving fixed-dose combination (FDC) inhaled corticosteroid/long-acting β 2 -agonist (ICS/LABA). Commercially insured from Optum Research Database were invited to complete Asthma Control Test (ACT) Questionnaire-6 (ACQ-6). Among participants ( N = 428), 36.4% (ACT-assessed) 55.6% (ACQ-6-assessed) had inadequately controlled...

10.1038/s41533-023-00336-9 article EN cc-by npj Primary Care Respiratory Medicine 2023-05-08

This study investigated burden of 'not well-controlled' asthma, overall and by Global Initiative for Asthma (GINA) Step, among treated asthma patients in Practice Fusion's research database. control (Asthma Control Test [ACT]) was stratified GINA Step; prevalence ratios were estimated using Poisson regression with robust variance controlled confounders. ACT scores ≤19 reflect not well-controlled; >19 'well-controlled' asthma. Of 15,579 patients, 30% had well-controlled at index date. The...

10.1038/s41533-023-00338-7 article EN cc-by npj Primary Care Respiratory Medicine 2023-04-27

e23106 Background: Pts with myelofibrosis (MF) often experience debilitating symptoms that negatively impact health-related quality of life and functioning. The MFSAF v4.0 is a 7-item questionnaire assessing the burden MF symptoms, including fatigue, night sweats, pruritus, abdominal discomfort, pain under left ribs, early satiety, bone pain. Each item evaluated on an 11-point numeric rating scale (NRS) from 0 (absent) to 10 (worst imaginable). We sought evaluate content validity in Janus...

10.1200/jco.2024.42.16_suppl.e23106 article EN Journal of Clinical Oncology 2024-06-01

There is limited information available on the impact of moderate asthma exacerbations, often called "asthma attacks" (i.e., those not requiring hospitalisation or treatment with systemic corticosteroids) patients' lives. This multi-country qualitative study explored patient experience these events.

10.1186/s41687-022-00506-2 article EN cc-by Journal of Patient-Reported Outcomes 2022-11-22

Detecting the quantity and diversity of diatoms is great significance in areas such as climate change, water quality assessment, oil exploration. Here, an efficient accurate object detection model, named SC-DiatomNet, proposed for diatom complex environments. This model based on YOLOv3 architecture uses K-means++ algorithm anchor box clustering dataset. A convolutional block attention module incorporated feature extraction network to enhance model’s ability recognize important regions....

10.3390/jmse12101862 article EN cc-by Journal of Marine Science and Engineering 2024-10-17

<b>Introduction:</b> Current published literature on clinical remission focuses the clinician's perspective. Patient perspective is required for better definition, communication and treatment approach. <b>Aims objectives:</b> To explore patients with asthma their current goals, knowledge perception of remission. <b>Methods:</b> This study surveyed an international online community 125 participants moderate to severe across 6 countries (France, Germany, Italy, Spain, Japan, USA). An...

10.1183/13993003.congress-2023.pa1895 article EN 05.01 - Airway pharmacology and treatment 2023-09-09

The retrospective, observational, self-controlled REMIT study enrolled 170 pts with SEA who started mepolizumab 100 mg SC Q4W, from 17 Taiwanese centres 12-month (mo) follow-up (FU). This post-hoc analysis of 167 (excluding 3 died during FU) assessed the proportion achieving CR after use in total (TP), biologic-naïve (BNP; TP excluding switching omalizumab) and biologic-switch (SP; switched populations. Criteria for 3-way composite were: no clinically significant exacerbations (CSE; oral...

10.1183/13993003.congress-2023.pa1906 article EN 05.01 - Airway pharmacology and treatment 2023-09-09
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