A5100436654- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Circadian rhythm and melatonin
- Testicular diseases and treatments
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Sexual Differentiation and Disorders
- Non-Invasive Vital Sign Monitoring
- Stress Responses and Cortisol
- Sleep and related disorders
- Healthcare Technology and Patient Monitoring
- Thermography and Photoacoustic Techniques
- Wireless Body Area Networks
- High Altitude and Hypoxia
- Educational Technology and Pedagogy
- EFL/ESL Teaching and Learning
- Animal testing and alternatives
- Energy and Environment Impacts
- Aquaculture Nutrition and Growth
- Birth, Development, and Health
- Advanced Chemical Sensor Technologies
- Sleep and Wakefulness Research
- Light effects on plants
- Ultrasonics and Acoustic Wave Propagation
- Parasite Biology and Host Interactions
- Hepatitis Viruses Studies and Epidemiology
Zunyi Medical University
2024-2025
Jishou University
2024
Soochow University
2012-2023
Xiamen University
2023
The University of Texas MD Anderson Cancer Center
2018-2021
Shandong Agricultural University
2019-2020
Zhengzhou University
2019
Henan Provincial People's Hospital
2019
University of California, Davis
2019
Magee-Womens Research Institute
2019
In male pre-pubertal cancer patients, radiation and chemotherapy impact future fertility by eradication of spermatogonial stem cells (SSCs). macaques, spermatogenesis could be regenerated intratesticular transplantation SSCs, but only a small percentage spermatozoa produced were donor origin. Transient hormone suppression with GnRH antagonist (GnRH-ant) enhanced spermatogenic recovery from transplanted SSCs.
Bisphenol A (BPA) is one of the most widely produced chemicals in world used production epoxy resins and polycarbonate plastics. BPA easily migrated from outer packaging to contents. Due lipophilic property, accumulated organisms. Perinatal low-dose exposure alters brain neural development later generations. In this study, after treatment, spontaneous movement zebrafish larvae cleavage period segmentation (1-24 hpf) was significantly decreased, with speed decreasing by 18.97% distance...
Cancer treatment of prepubertal patients impacts future fertility due to the abolition spermatogonial stem cells (SSCs). In macaques, spermatogenesis could be regenerated by intratesticular transplantation SSCs, but no studies have involved cytotoxic before puberty and after puberty, which would most likely clinical scenario.To evaluate donor-derived functional sperm production SSC adult monkeys that had received testicular irradiation during period.We obtained testis tissue unilaterally...
The biological alteration of circadian rhythm was found to be related the development metabolic disorders. Our previous studies reported that impaired lipid metabolism caused by a high-fat diet improved oat fiber, but did not attempt answer whether improvement is mechanistically linked rhythm. By focusing on alteration, present study aimed elucidate effect gut microbiota-derived short chain fatty acids (SCFAs) in experimental paradigm with and without dietary fiber feeding. results showed...
Recent experimental animal studies suggested that the circadian locomotor output cycles kaput protein gene (CLOCK) has been reported to play a critical role in sperm function and male fertility. The aim of this study was determine whether variants CLOCK are involved idiopathic infertility. included 478 infertile men 194 fertile controls who completed physical examinations. Each subject donated 5 ml peripheral blood sample semen ejaculate. An aliquot each used separate serum for measurement...
Can transplanted primate testicular cells form seminiferous tubules de novo, supporting complete spermatogenesis?Cryopreserved from a prepubertal monkey can reorganize in an adult recipient testis forming novo tubular cords spermatogenesis.De morphogenesis of tissue using aggregated non-primate species grafted either subcutaneously or the support spermatogenesis.Two postpubertal rhesus monkeys (Macaca mulatta) were given irradiation. One was GnRH-antagonist treatment 8 to 16 weeks after...
Objective The purpose of this study was to characterize the metabolomic profiles shift workers and day discover effect work on workers’ metabolic health. Methods A total 824 participants aged 25 55 years were recruited, 485 (275 210 workers) completed study. mean age 37.32 (5.53) old, that 36.50 (7.83) old. Serum salivary samples collected for detection key biochemical indicators (melatonin, cholesterol, low‐density lipoprotein cholesterol) metabolome profile analyses. Results Compared with...
ABSTRACT Fenvalerate (Fen), a widely used pesticide, is known to impair male reproductive functions by mechanisms that remain be elucidated. Recent studies indicated circadian clock genes may play an important role in successful reproduction. The aim of this study was determine the effects Fen on involved biosynthesis testosterone using TM3 cells derived from mouse Leydig cells. Data demonstrated rhythm synthesis disturbed following treatment as evidenced changes rhythmicity core (Bmal1,...
At present, wearable blood oxygen devices on the market are mainly based wristband, which is convenient but greatly influenced by wrist activities. In this paper, we design a ear system, selecting earlobe as measurement point to reduce impact of The Photoplethysmography(PPG) signal collected reflective sensor and processed through Bluetooth chip NRF52832. Morphological filtering applied filter noise baseline drift. measuring results, saturation(SpO2) heart rate(HR), sent smart phone via...
Summary Studies have indicated that psychological stress impairs human fertility and various stressors can induce apoptosis of testicular cells. However, the mechanisms by which on males reduces semen quality in cells are largely unclear. Using a (restraint) mouse model, we tested whether male triggers spermatozoa spermatogenic through activating tumour necrosis factor (TNF)-α signalling. Wild-type or TNF-α −/− mice were restrained for 48 h before examination expression TNF receptor 1...
The mechanisms by which psychological stress impairs semen quality are largely unknown. By using a restraint-stressed mouse model, we studied the role of FasL/Fas system in stress-induced apoptosis spermatozoa and spermatogenic cells. Male mice were restrained for 48 h before examination sperm fertilizing potential expression spermatozoa, spermatogenetic cells/seminiferous tubules, caudae epididymides. results showed that male restraint reduced motility, fertilization rates, mitochondrial...
To investigate the expression pattern of rat Eppin (epididymal protease inhibitor; official symbol Spinlw1), we detected mRNA transcripts and subsequent protein translation in several sorts tissues by RT-PCR western blotting. Then immunohistochemistry was performed for more detailed observation. The testicular transcription level monitored real-time PCR throughout postnatal development. We found that specifically expressed testis epididymis. slight neonatal (1-day) infantile stages (5-, 7-...
Infertility is known to occur frequently worldwide, and the incidence continuing rise in China. It that semenogelin (SEMG) protein secreted by human seminal vesicles plays an important role male reproductive system function. However, association between alterations SEMG gene functions idiopathic infertility occurrence Chinese-Han population has not been examined. The aim of this study was thus investigate inherent relationship using a method variant genotyping selection semen quality...
(Abstracted from Hum Reprod 2018;33:2249–2255) Cytotoxic cancer treatments, including chemotherapy and radiotherapy, cause damage to spermatogenic stem cells (SSCs), jeopardizing the fertility of young men reproductive age. One potential method for future production sperm in this population is SSC transplantation.
Acute kidney injury (AKI) is a common, fatal complication of acute cholangitis (AC). The link between AC and AKI poorly understood.
ECG signals are the most commonly used in heart disease detection. It contains many waveforms that directly related to cardiac activity, where T wave much important physiological information. The position detection algorithm is based on differential threshold method, and morphological judgment before includes three parts: preprocessing, judgment, Firstly, signal preprocessed eliminate effects of noise other waves. Secondly, a window defined realize judgment. Finally, morphology, obtained by...