A5003255265- Diet and metabolism studies
- Neuroscience and Neuropharmacology Research
- Adenosine and Purinergic Signaling
- Diet, Metabolism, and Disease
- Adipose Tissue and Metabolism
- Cardiovascular Function and Risk Factors
- Epilepsy research and treatment
- Metabolism and Genetic Disorders
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Ion channel regulation and function
- Tryptophan and brain disorders
- Genetics and Neurodevelopmental Disorders
- Manufacturing Process and Optimization
- Business Process Modeling and Analysis
- Cardiac electrophysiology and arrhythmias
- Stress Responses and Cortisol
- Neural dynamics and brain function
- Photoreceptor and optogenetics research
- Dental materials and restorations
- Flexible and Reconfigurable Manufacturing Systems
- Thyroid Disorders and Treatments
- Bipolar Disorder and Treatment
- Cancer, Hypoxia, and Metabolism
- Neurological Complications and Syndromes
Semilab (Hungary)
2013-2024
Eötvös Loránd University
1998-2024
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș
2024
Babeș-Bolyai University
2022-2023
University of Debrecen
2016-2021
University of Szeged
2003-2021
HUN-REN Wigner Research Centre for Physics
2021
University of Sopron
2009-2020
Szent János Kórház
2017-2020
Savaria (Canada)
2019
Nutritional ketosis has been proven effective for seizure disorders and other neurological disorders. The focus of this study was to determine the effects ketone supplementation on anxiety-related behavior in Sprague-Dawley (SPD) Wistar Albino Glaxo/Rijswijk (WAG/Rij) rats. We tested exogenous supplements added food fed chronically 83 days SPD rats administered sub-chronically 7 both rat models by daily intragastric gavage bolus followed assessment anxiety measures elevated plus maze (EPM)....
The state of therapeutic ketosis can be achieved by using the ketogenic diet (KD) or exogenous ketone supplementation. It was suggested previously that adenosinergic system may involved in mediating effect KD on suppressing seizure activity different types epilepsies, likely means adenosine A1 receptors (A1Rs). Thus, we tested present study whether supplements (ketone ester: KE, 2.5 g/kg/day; salt/KS + medium chain triglyceride/MCT: KSMCT, g/kg/day) applied sub-chronically (for 7 days)...
Accumulating evidence indicate that astrocytes are essential players of the excitatory and inhibitory signaling during normal epileptiform activity via uptake release gliotransmitters, ions, other substances. Polyamines can be regarded as gliotransmitters since they almost exclusively stored in released by various mechanisms. The polyamine putrescine (PUT) is utilized to synthesize GABA, which also from provide tonic inhibition on neurons. spermine (SPM), synthesized form PUT through...
Diseases involving inflammation and oxidative stress can be exacerbated by high blood glucose levels. Due to tight metabolic regulation, safely reducing prove difficult. The ketogenic diet (KD) reduces absolute insulin, while increasing fatty acid oxidation, ketogenesis, circulating levels of β-hydroxybutyrate (βHB), acetoacetate (AcAc), acetone. Compliance KD difficult, so alternative therapies that help reduce are needed. Exogenous ketones provide an method elevate ketone without strict...
Anxiety disorders are one of the most common mental health problems worldwide, but exact pathophysiology remains largely unknown. It has been demonstrated previously that administration exogenous ketone supplement KSMCT (ketone salt/KS + medium chain triglyceride/MCT oil) by intragastric gavage for 7 days decreased anxiety level in genetically absence epileptic Wistar Albino Glaxo/Rijswijk (WAG/Rij) rats. To investigate potential role adenosinergic system pathomechanism we tested whether...
Abstract Introduction Lipedema is a barely recognized and poorly diagnosed, but common disease affecting almost exclusively female patients. The pathomechanism of lipedema not known, clinically, it bilateral, symmetrical, disproportional fatty enlargement the lower half body, does affect feet, upper extremities are often involved. Since associated with increased aortic stiffness altered left ventricular (LV) rotational mechanics, present study was designed to compare size function mitral...
The overall goal of this study is to describe the methodology elevated plus maze (EPM) test in combination with a video tracking software. purpose method document effect various potential anxiolytic treatments on laboratory rodent models. EPM based rodents' proclivity toward protected, enclosed dark spaces and unconditioned fear open heights, their innate intense motivation explore novel environments. widely used behavioral for investigating or anxiogenic responses rodents given drugs that...
The influence of astrocytic cell networks on neuronal network activity is an emerging issue in epilepsy. Among the various mechanisms by which astrocytes modulate function, synchronization via gap junction channels widely considered to be a crucial mechanism epileptic conditions, contributing networks, possibly inducing recurrent epileptiform activity. Here we explored whether modulation junctions could alter seizures different types Opening trimethylamine intensifies seizure-like events...
To assess its differential diagnostic value, dehydroepiandrosterone sulfate (DHEA-S) was measured in a nonselected cohort of 84 patients with incidentally detected adrenal tumors (incidentaloma). Of the 38 histologically confirmed cases, 6 12 primary or metastatic malignant tumor adrenals and 7 14 benign cortical adenoma had low DHEA-S levels. Thus, sensitivity, specificity, predictive value level to indicate were 0.35, 0.50, 0.60, values 0.67, 0.47, respectively. cases adenoma, 10 signs...