In Brief We studied the relationship between timing of discontinuing chronic angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptor subtype 1 antagonists (ARA) hypotension after induction general anesthesia in a surgical population. retrospectively 267 hypertensive patients receiving ACEI/ARA therapy undergoing elective noncardiac surgery under anesthesia. During preoperative visits, were asked to either take their last on morning or withhold it up 24 h before surgery....

Sleep loss in attending physicians has an unclear effect on patient outcomes. In this study, we examined the of medical care provided by after midnight outcomes their scheduled elective procedures performed during day.We conducted a population-based, retrospective, matched-cohort study Ontario, Canada. Patients undergoing 1 12 daytime physician who had treated patients from to 7 a.m. were matched 1:1 ratio same procedure day when not midnight. Outcomes included death, readmission,...

Breast cancer is one of the leading cause mortality and morbidity in Canada. Screening most promising approach identification treatment disease at early stage its development. Research shows higher rate breast among ethno-racial immigrant women despite their lower incidence which suggests disparities mammography screening. This study aimed to compare prevalence appropriate screening native borne determine predicators low We conducted secondary data analyses on Ontario linked social health...

Abstract Rates of mammography screening for breast cancer are disproportionately low in certain subgroups including low‐income and immigrant women. The purpose the study was to examine differences rates appropriate (i.e., every 2 years) among Ontario women by world region origin explore association between these groups individual structural factors. A cohort 183,332 screening‐eligible living 2010 2012 created from linked databases classified into eight regions origin. Appropriate were...

Introduction We aimed to develop algorithms distinguishing type 1 diabetes (T1D) from 2 in adults ≥18 years old using primary care electronic medical record (EMRPC) and administrative healthcare data Ontario, Canada, estimate T1D prevalence incidence. Research design methods The reference population was a random sample of patients with EMRPC whose charts were manually abstracted (n=5402). Algorithms developed classification trees, forests, rule-based methods, (EMR) data, or both. Algorithm...

Background: Metabolic syndrome (MetS) is a risk factor for development of cancer. Because aberrant lipid metabolism pathogenic feature chronic lymphocytic leukemia (CLL), our objective was to determine if CLL patients have higher prevalence MetS preceding diagnosis and the impact lipid-lowering medications on survival. Methods: We conducted population-based case-control study in Ontario, Canada, using administrative databases adults age 66 years older compare with age- sex-matched control...

<h3>Background:</h3> Opioids are an important pain therapy, but their use may be associated with adverse events in frail and cognitively impaired long-term care residents. The objective of this study was to investigate trends opioid prescribing among Ontario residents over time, given the paucity data for setting. <h3>Methods:</h3> We used linked clinical health administrative databases conduct a population-based, repeated cross-sectional between Apr. 1, 2009, Mar. 31, 2017. identified...

Audit and feedback reports, distributed by Health Quality Ontario to consenting primary care physicians, provide doctors with a confidential summary of how they manage patients diabetes; these reports currently lack clinical information.We examined the feasibility linking Laboratories Information System (OLIS), large provincial database laboratory test results, existing audit reporting structure integrate measures glycemic cholesterol control among diabetes.We found that we could ascertain...

Numerous medical interventional procedures, such as brachytherapy, biopsy, radio frequency based thermal ablation, and anesthetic drug delivery, require precise placement of needles. Most these interventions are performed percutaneously. However, the needle to a specific target inside human body is difficult task. Furthermore, involved needles usually rigid straight, real-time sensory feedback rarely available. Medical imaging delivery systems have undergone significant growth in recent...

Background Breast cancer is one of the leading cause mortality and morbidity in Canada. Screening most promising approach identification treatment disease at early stage its development. Research shows higher rate breast among ethno-racial immigrant women despite their lower incidence which suggests disparities mammography screening. This study aimed to compare prevalence appropriate screening native borne determine predicators low Methods We conducted secondary data analyses on Ontario...

Background Breast cancer is one of the leading cause mortality and morbidity in Canada. Screening most promising approach identification treatment disease at early stage its development. Research shows higher rate breast among ethno-racial immigrant women despite their lower incidence which suggests disparities mammography screening. This study aimed to compare prevalence appropriate screening native borne determine predicators low Methods We conducted secondary data analyses on Ontario...

Shivering compromises post‐operative recovery and patient comfort. is also an impediment to targeted temperature management (TTM), now standard of care for cardiac arrest. Without effective drug suppress shivering (referred here as a thermolytic) high cost difficulty restricting access TTM outside large hospitals conditions such stroke. A more efficacious thermolytic needed control improve comfort during TTM. Our prior work in rats, based on strong scientific premise from the study...

IntroductionImproving the care and management of patients with diabetes, particularly those extreme blood glucose and/or cholesterol levels, has been identified as a key priority area for healthcare in Ontario. A multi-organizational collaboration produces audit-and-feedback reports distributed to consenting primary physicians across province quality improvement purposes.&#x0D; Objectives ApproachWe examined feasibility linking Ontario Laboratory Information System (OLIS), large nearly...

Busy, practicing anesthesiologists are often looking for a method to familiarize themselves with new medical knowledge, techniques, and equipment but challenged do so in an evidence-based fashion.This first volume of The Year Anaesthesia Critical Care aims just that.It is geared toward providing the clinician balanced view recent literature commentaries from stellar, international group editors.Rather than being comprehensive, editors have chosen four topic areas development: perioperative...

Electronic Medical Record (EMR) data are an efficient method for constructing large type 1 diabetes (T1D) cohorts but limited by availability of accurate diagnosis codes. We sought to derive algorithm identifying T1D using Records - Primary Care (EMRPC) also known as EMRALD, a database including records from &amp;gt;300,000 primary care patients in Ontario, Canada. A 25% random sample adults with and at least year EMRPC prior September 30, 2015 formed the reference cohort. Charts potential...