A5016772805- Viral Infections and Vectors
- Vector-borne infectious diseases
- Mosquito-borne diseases and control
- Respiratory viral infections research
- Tracheal and airway disorders
- Vector-Borne Animal Diseases
- Study of Mite Species
- Plant Reproductive Biology
- Respiratory and Cough-Related Research
- Microfluidic and Capillary Electrophoresis Applications
- Geology and Paleoclimatology Research
- Antibiotic Resistance in Bacteria
- Leptospirosis research and findings
- Evolution and Paleontology Studies
- Nanopore and Nanochannel Transport Studies
- Garlic and Onion Studies
- Monoclonal and Polyclonal Antibodies Research
- Natural product bioactivities and synthesis
- Plant tissue culture and regeneration
- Bacteriophages and microbial interactions
- vaccines and immunoinformatics approaches
- Genetics, Bioinformatics, and Biomedical Research
- Neurobiology and Insect Physiology Research
- Antimicrobial Resistance in Staphylococcus
- Advanced biosensing and bioanalysis techniques
Universidade Federal de Uberlândia
2012-2023
Centers for Disease Control and Prevention
2012
Universidade de São Paulo
1999
Next-generation sequencing allows the analysis of an unprecedented number viral sequence variants from infected patients, presenting a novel opportunity for understanding virus evolution, drug resistance and immune escape. However, in bulk is error prone. Thus, generated data require identification correction. Most error-correction methods to date are not optimized amplicon assume that rate randomly distributed. Recent quality assessment sequences obtained using 454-sequencing showed...
We described a comprehensive analysis of the molecular epidemiology multidrug-resistant (MDR) P. aeruginosa. Molecular included typing by Pulsed Field Gel Electrophoresis, identification genes interest through PCR-based assays and sequencing target genes. Case-control study was conducted to better understand prognostic patients impact inappropriate therapy in with bacteremia, as well risk factors MDR infections. observed high rate isolates (40.7%), 51.0% them independently associated...
Respiratory syncytial virus (RSV) is a major cause of acute respiratory disease in infants and young children. Considering that several aspects the humoral immune response to RSV infection remain unclear, this study aimed investigate occurrence, levels, avidity total IgG, IgG1, IgG3 antibodies against serum samples from children ≤5 years old. In addition, possible association between antibody severity illness was examined. The occurrence levels RSV-specific IgG depended on age, with <3...
Vaccine development against hepatitis C virus (HCV) is hindered by poor understanding of factors defining cross-immunoreactivity among heterogeneous epitopes. Using synthetic peptides and mouse immunization as a model, we conducted quantitative analysis variants the HCV hypervariable region 1 (HVR1). Analysis 26,883 immunological reactions pairs showed that distribution HVR1 was skewed, with antibodies few reacting all tested peptides. The accurately modeled based on amino acid sequence...
Abstract The human metapneumovirus (hMPV) is a pathogen of the respiratory tract identified first in Netherlands 2001 and since then it has been detected worldwide. purpose this study was to identify characterize hMPV samples collected from children <5 years presenting with acute disease (ARD) seen at public hospital Uberlândia, Southeastern Brazil. One hundred fourteen nasopharyngeal aspirates (NPAs) that were negative for presence nine other viruses tested by reverse transcription...
Viral respiratory disease constitutes a great burden worldwide mainly among children.One pursued to compare characteristics of children who required hospitalization from those did not require due viral disease.Medical and demographic data were collected through questionnaires nasopharyngeal aspirates tested for detection viruses in outpatients up five years old, presenting acute infection.Respiratory syncytial virus predominated hospitalized while other (Human rhinovirus, Influenza virus,...
Human rhinoviruses (HRV) are usually associated with mild respiratory symptoms in children. However, some studies have found that HRV can cause severe disease, especially when the patient is co-infected a second virus. In this study, 532 nasopharyngeal aspirates (NPAs) were collected over nine-year period from children at Clinics Hospital of Uberlândia. The NPAs then tested for RNA using reverse transcription-polymerase chain reaction. Eighty-three specimens diagnosed lower tract illness...
The dengue virus is responsible for a high worldwide incidence of infections, aggravated by late diagnosis, and often confused with other tropical diseases. Results/methodology: Oligonucleotide aptamers binding to the 5'-UTR from selected after eight rounds systematic evolution ligands exponential enrichment technology were analyzed dot-blot assay in silico prediction secondary structures, demonstrating presence stem-loops that may have potential interaction viral genome, which can lead loss...
Influenza remains a major health problem due to the seasonal epidemics that occur every year caused by emergence of new influenza virus strains. Hemagglutinin (HA) and neuraminidase (NA) glycoproteins are under selective pressure subjected frequent changes antigenic drift. Therefore, our main objective was investigate cases in Uberlândia city, Midwestern Brazil, order monitor appearance viral strains, despite availability prophylactic vaccine. Nasopharyngeal samples were collected from 605...
Ticks are obligate hematophagous parasites that can transmit to vertebrate hosts several pathogens, including viruses, bacteria, protozoa and helminths. Among these agents, some Borrelia species cause disease in humans other hosts; therefore, they have medical veterinary health importance. To gather additional information on Brazil, the current study aimed detect presence of Ornithodoros cavernicolous ticks collected September 2019 from cement pipes used by bats as shelter a farm located...
Background Leptospirosis is a zoonosis caused by the infection of pathogenic bacteria genera Leptospira, often transmitted direct or indirect contact with urine infected animal hosts [1]. In national territory, leptospirosis considered an endemic disease, high incidence in raining seasons, but occurring during whole year [2]. From all cases, 15% evolve to icteric form, serious clinic manifestations, as severe icteric, hemorrhages and kidney including lethal onset 50% cases [3]. membrane...
Ticks are obligate hematophagous parasites that transmit to vertebrate hosts several pathogens, such as viruses, bacteria, protozoa and helminths. Among these agents, some Borrelia species may cause diseases, which even be fatal humans other and, therefore, have great human veterinary public health importance. To gather additional information on the circulation of in Brazil, current study aimed molecularly detect presence Ornithodoros carvernicolous ticks collected from cement pipes were...