A5061136406- Breast Cancer Treatment Studies
- HER2/EGFR in Cancer Research
- Breast Lesions and Carcinomas
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Estrogen and related hormone effects
- Cancer Genomics and Diagnostics
- Genetic factors in colorectal cancer
- Gastrointestinal Tumor Research and Treatment
- Breast Implant and Reconstruction
- Cancer Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Neuroendocrine Tumor Research Advances
- Colorectal and Anal Carcinomas
- Monoclonal and Polyclonal Antibodies Research
- Cancer, Hypoxia, and Metabolism
- Cancer Treatment and Pharmacology
- Lung Cancer Treatments and Mutations
- Cancer Risks and Factors
- Colorectal Cancer Treatments and Studies
- Peptidase Inhibition and Analysis
- Tumors and Oncological Cases
- Gut microbiota and health
- Cancer-related Molecular Pathways
- Pancreatic and Hepatic Oncology Research
European Institute of Oncology
2013-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2023
University of Milan
2004-2022
Santa Maria Nuova Hospital
2013
University of Perugia
2013
Azienda Ospedaliera S.Giuseppe Moscati
2011
Ripamonti
2007
Ospedale Maggiore
2004-2006
Ospedale San Paolo
2006
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2004
A gut bacterial containment system Trillions of bacteria selectively inhabit our guts, but how do bodies keep them contained? Spadoni et al. describe a “gut-vascular barrier” that prevents intestinal microbes from accessing the liver and bloodstream in mice (see Perspective by Bouziat Jabri). Studies with human samples revealed cell biology gut-vascular barrier shares similarities blood-brain central nervous system. Pathogenic such as Salmonella typhimurium could penetrate mice, gaining...
Objective: The aim of this study was to compare robotic mastectomy with open classical technique outcomes in breast cancer patients. Summary Background Data: As the use nipple sparing continues rise, improved understanding surgical, oncologic, and quality life is imperative for appropriate patient selection as well better understand indications, limits, advantages, dangers. Methods: In a phase III, label, single-center, randomized controlled trial involving 80 women (69) or BRCA mutation...
Although invasive lobular carcinoma (ILC) is the second most common histotype of breast cancer, prognostic implications its clinicopathologic characteristics remain controversial.The authors undertook a retrospective analysis large series cases treated and followed at single institution, with objective assessing prognostic/predictive value distinct features tumors, after revision original histopathologic preparations statistical analyses.Overall, 530 patients pure ILC (57% classic type; 19%...
Metformin has been associated with antitumour activity in breast cancer (BC) but its mechanism remains unclear. We determined whether metformin induced a modulation of apoptosis by terminal deoxynucleotidyl transferase dUTP nick end labelling (TUNEL) overall and insulin resistance status presurgical trial.Apoptosis was analysed core biopsies surgical samples from 100 non-diabetic BC patients participating randomised trial vs placebo given for 4 weeks before surgery.Eighty-seven subjects (45...
Abstract Introduction Metaplastic breast cancer (MBC) is a rare condition of tumor with different subtypes, considered disease worse prognosis; treatments and survival are often unclear conflicting. Methods We consecutively collected 153 primary MBCs subtypes. Breast surgery, neoadjuvant or adjuvant treatment, clinic‐pathological factors, number type events during follow‐up were to evaluate overall (OS) invasive disease‐free (IDFS). Results The majority MBC was triple‐negative (TN) subtype...
Preoperative endocrine therapy is effective in postmenopausal patients with breast cancers expressing oestrogen receptor. We investigated the activity of primary letrozole combination GnRH analogue premenopausal women T2–T4 N0–N2 cancer, whose tumours expressed and progesterone receptors. measured expression molecular factors involved responsiveness to agents including ERα, EGFR, HER2, MAP kinases (and phosphorylated forms) ER-β1, both at initial biopsy time surgery. Thirty-five were...
Several studies suggest a role of gut microbiota in colorectal cancer (CRC) initiation and progression. Vitamin D (vitD) blood levels are also inversely correlated with CRC risk prognosis. However, these factors' interplay remains unknown.