A5013617328- Ethnobotanical and Medicinal Plants Studies
- Essential Oils and Antimicrobial Activity
- Moringa oleifera research and applications
- Phytochemistry and Biological Activities
- Drug-Induced Hepatotoxicity and Protection
- Pesticide Exposure and Toxicity
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Malaria Research and Control
- Insect Pest Control Strategies
- Traditional and Medicinal Uses of Annonaceae
- Research on Leishmaniasis Studies
- Child Nutrition and Water Access
- Botanical Research and Chemistry
- Parasites and Host Interactions
- African Botany and Ecology Studies
- Infectious Diseases and Tuberculosis
- Menstrual Health and Disorders
- Toxin Mechanisms and Immunotoxins
- Diagnosis and treatment of tuberculosis
- Herbal Medicine Research Studies
- Trypanosoma species research and implications
- Natural Antidiabetic Agents Studies
- Plant Toxicity and Pharmacological Properties
- Diverse Scientific Research Studies
Addis Ababa University
2014-2024
Zoological Institute
2022
Ethiopian Public Health Institute
2021
Laboratoire des Sciences de l’Information et de la Communication
2021
Metropolitan University College
2021
Kotebe University of Education
2021
Arba Minch University
2021
United Arab Emirates University
2021
Wollo University
2020
Mekelle University
2013
Pesticide sprayers from five state‐owned agricultural farms took part in a study that evaluated their knowledge, attitude and practice of pesticide use on farms. Demographic features the showed majority them had primary‐level education. The duration work as ranged 1 month to ∼10 years, with 59% having worked for <5 years. Their knowledge about hazards pesticides was indicated by responses they gave standard questionnaire. Careful working considered be very important 93% them, while only 7%...
Background Alternative treatments for visceral leishmaniasis (VL) are required in East Africa. Paromomycin sulphate (PM) has been shown to be efficacious VL treatment India. Methods A multi-centre randomized-controlled trial (RCT) compare efficacy and safety of PM (20 mg/kg/day 21 days) plus sodium stibogluconate (SSG) combination (PM, 15 SSG, 20 17 with SSG 30 Patients aged 4–60 years parasitologically confirmed were enrolled, excluding patients contraindications. Primary secondary outcomes...
Ajuga remota Benth is traditionally used in Ethiopia for the management of diabetes mellitus. Since this claim has not been investigated scientifically, aim study was to evaluate antidiabetic effect and phytochemical screening aqueous 70% ethanol extracts on alloxan-induced diabetic mice. After acute toxicity test, Swiss albino mice were induced with alloxan get experimental animals. The fasting mean blood glucose level before after treatment two weeks normal, untreated treated performed....
The essential oils obtained by hydrodistillation from fresh leaves of Cymbopogon citratus and Ocimum gratissimum growing in Cameroon were analyzed GC GC/MS. main constituents the oil γ-terpinene (21.9 %), β-phellandrene (21.1 limonene (11.4 %) thymol (11.2 while contained geranial (32.8 neral (29.0 myrcene (16.2 β-pinene (10.5 %). effects these on growth Plasmodium berghei investigated. Both showed significant antimalarial activities four-day suppressive vivo test mice. At concentrations...
Background: Malaria caused by the parasite Plasmodium falciparum is an acute disease which kills estimated 863,000 people per year according to WHO report of 2009. The fight against malaria faced with occurrence widespread resistance P. falciparum. search for plant-derived antimalarial drugs has great importance in this regard. Thus study evaluates toxicity and activity extracts Clerodendrum myricoides, Dodonia angustifolia Aloe debrana.Method: Acute sub studies were carried out giving up...
Schistosomiasis is endemic in Ethiopia and previously unknown transmission foci have been reported from time to different parts of the country. Further surveys are required areas where endemicity disease not known cover them with control program if taking place. This study, therefore, aims assess magnitude schistosomiasis mansoni soil-transmitted helminthiasis Maksegnit Enfranz Towns, northwestern Ethiopia. Cross-sectional parasitological malacological were conducted three schools found...
Fever of different etiology is common in tropical and subtropical countries the world. Etiological agents febrile illnesses were assessed 653 acute patients aged 3 to 17 years who attended outpatient departments Dembecha Health Center, Jiga Quarit Finoteselam Hospital western Gojjam zone, northwestern Ethiopia. Malaria was most prevalent illness, infecting 62% all cases. Its prevalence varied significantly from 52% (Dembecha) 72.7% (Quarit) (χ2 = 15.02, P 0.000). Plasmodium falciparum first...
Visceral leishmaniasis (VL) has been known to exist in northwest Ethiopia (Humera-Metema lowlands) since the early 1970s associated with large scale agricultural development activities, often resulting outbreaks. The latest outbreak of disease that started around 1995 both regions, led present preliminary entomological surveys (1996-2005) results which are reported here. Sandflies were collected using CDC light traps and Phlebotomus females dissected for Leishmania detection isolation;...
Background: Moringa stenopetala and related species are commonly used in folk medicine for various human diseases such as antimalarial, antihypertensive, antidiabetic antispasmodic. Objective: The aim of the study is to evaluate effects aqueous extract M. on blood parameters, histopathology liver kidney experimental mice. Methods: Fresh leaves were collected from Arbaminch area, Southwest Ethiopia, November 2005. dried extracted with water. Three month-old Swiss albino male mice, which kept...
Abstract Background The negative impact of synthetic molluscicides on the environment and their high cost necessitated search for an alternative approach using plant extracts control schistosomiasis. objective this study was, therefore, to evaluate aqueous ethyl acetate crude Glinus lotoides fruits cercariacidal activity molluscicidal effect against schistosome snail intermediate hosts. Methods Assessment Biomphalaria pfeifferi was made by immersion method in accordance with WHO guideline....
<br><b><i>Objective/Background:</i></b> Multidrug-resistant tuberculosis (MDR-TB) is growing globally and becoming a major challenge for national TB control programs. Therefore, rapid identification of MDR strains <i>Mycobacterium tuberculosis</i> monitoring their transmission could contribute significantly to the TB. The GenoType MTBDR<i>plus</i> assay has been recommended by World Health Organization identify rifampicin (RIF)- isoniazid (INH)-resistant <i>M. Tuberculosis</i> isolates. This...
Cross-cultural studies indicate that every culture has its own particular explanations for health and illness healing strategies. The Konso people have always practiced indigenous medicine multifaceted accounts or multiple dimensions of perceptions health-care beliefs practices. This paper describes how are instrumental in treatment outcomes among the southwestern Ethiopia. Results may provide an understanding relation to local cosmology, religion, environment.The ethnographic method was...
Background: Moringa stenopetala, Baker f. (Moringaceae) is used for food and medicine in Southern Ethiopia.Objective: To substantiate the hypotensive effect of M. stenopetala vivo vitro.Methods: An experiment was carried out on male guinea pigs anaesthetized with pentobarbital. The arterial blood pressure recorded from a carotid artery filled heparinized saline via an cannula connected to transducer. For vitro descending thoracic aorta removed kept moistened Krebs-Henseleit solution then...
Identification of the types strains Mycobacterium tuberculosis (M. tuberculosis) complex causing (TB) could contribute to TB control program specific geographic region as well it add knowledge onto existing literature on worldwide. The objective present study was identify species and M. pulmonary in central Ethiopia. A health institution- based cross-sectional conducted 338 smear positive cases visiting three hospitals between October 2012 September 2013. Morning spot sputum samples were...
Coffee is among the most traded commodities and consumed beverages worldwide primarily for its stimulating effects. Moreover, coffee known to contain various bioactive compounds with significant health benefits including antibacterial antioxidant activities. However, Ethiopia as origin of producer exporter varieties Coffea arabica has made little study on aspects this beverage. The aim was examine activities content samples from different localities Yorgacheffe Jimma; roasted, ground, packed...
The leaves and the root extracts of Moringa stenopetala were tested in vitro against trypomastigotes Trypanosoma brucei, cruzi L. donovani amastigotes. fresh wood ethanol extract dried acetone found to be active T. brucei with an ED50 value 9.2 µg/mL 10.0 respectively. All other inactive all parasite forms. Copyright © 1999 John Wiley & Sons, Ltd.
Crude and column chromatographic fractions of methanol leaf extract Jatropha curcas were tested for their larvicidal activities against laboratory reared late third instar larvae Anopheles arabiensis. J .curcas had similar activity to 0.5 ppm Temephos (positive control) at test concentrations ranging from 125 -1000 while (F1 F2 ) the crude J.curcas showed 62.5 concentrations. Column fraction three (F3) concentration. The LC50 LC90 values found be 92.09 241.09 ppm, respectively. Toxic one...
Drug resistance tuberculosis (TB) and the emergence of multidrug resistant (MDR) isolates are significant concerns regarding TB control programs in several countries. This study was undertaken to evaluate drug sensitivity Mycobacterium assess its association with strains lineages M. tuberculosis. A total 279 isolated from Central Ethiopia were tested for their patterns first line drugs using conventional proportion method on Löwenstein Jensen media. The between strain type assessed 263...
Dodonaea angustifolia is used in Ethiopian traditional medicine to treat malaria. The objective of this work was conduct bioassay guided fractionation the leaves D. using Plasmodium berghei infected mice.
In this study, we evaluated the antibacterial activities of essential oils (EOs) Thymus serrulatus and schimperi collected from Ofla (Ofl), Alamata (Ala), Yilmana Densa (Yil), Tarmaer (Tar), Butajira (Buta), Bale (Bal) in Ethiopia against cariogenic bacteria (Streptococcus mutans Lactobacillus) isolated human teeth. Inhibition zones (IZs), minimum inhibitory concentrations (MICs), bactericidal (MBCs) were measures activity. Significant bacterial inhibitions resulted a dose-and EO-dependent...
The fresh leaf ethanol (LE) extract of Moringa stenopetala was tested in guinea-pig ileum and mouse duodenum uterus strips. There were significant dose time dependent reductions the acetylcholine (AC) response with initial stimulatory effects both preparations. Spontaneous rhythmic contractions greatly reduced, suggesting an antispasmodic property crude LE extract. showed some oxytocic activity on strips guinea-pigs mice. results are indicative traditional use leaves for stomach pain to...