A5023254616- Seed and Plant Biochemistry
- Microbial Metabolites in Food Biotechnology
- Plant Gene Expression Analysis
- Food composition and properties
- Plant Molecular Biology Research
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Plant Genetic and Mutation Studies
- Plant Stress Responses and Tolerance
- Phytochemicals and Antioxidant Activities
- Advances in Cucurbitaceae Research
- Magnetic and Electromagnetic Effects
- Cancer-related gene regulation
- Nutrition, Genetics, and Disease
- Plant biochemistry and biosynthesis
- Circular RNAs in diseases
- Plant tissue culture and regeneration
- Digestive system and related health
- Phytase and its Applications
- Transgenic Plants and Applications
- Biofuel production and bioconversion
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neonatal Respiratory Health Research
- Plant nutrient uptake and metabolism
- Light effects on plants
Sichuan Agricultural University
2022-2025
First Affiliated Hospital of Jiangxi Medical College
2025
Xichang University
2024
Nanchang University
2022
First Affiliated Hospital of Nanchang University
2022
Anthocyanins and proanthocyanidins (PAs) are vital secondary metabolites in Tartary buckwheat because of their antioxidant capacities radical scavenging functions. It has been demonstrated that R2R3-MYB transcription factors (TFs) essential regulators anthocyanin PA biosynthesis many plants. However, regulatory mechanisms remain to be clarified. Here, we confirmed the role FtMYB3 biosynthesis. FtMYB3, which belongs subgroup 4 R2R3 family was predominantly expressed roots. The transcriptional...
Tartary buckwheat (Fagopyrum tataricum Gaertn.) is a coarse cereal with strongly abiotic resistance. The MYB family plays regulatory role in plant growth, development, and responses to biotic stresses. However, the characteristics mechanisms of transcription factors remain unclarified. Here, this study cloned FtMYB22 gene from buckwheat, investigated its involvement responding individual water deficit salt stress Arabidopsis. Sequence analysis highlighted that N-termini contained two highly...
Background: Bone marrow mesenchymal stem cell (BMSC) therapy is a novel approach for treating COPD. However, the difficulty in engraftment and easy clearance of BMSCs vivo has hindered their clinical application. Hence, exploring effective methods to improve differentiation rates urgent. Methods: We constructed overexpressing Wnt3a by lentivirus infection transplanted them into COPD rat model. The damage level lung tissue was assessed pathology analysis inflammatory cytokines analysis. BMSC...
Rutin-degrading enzymes play a crucial role in catalyzing the hydrolysis of rutin (quercetin 3-O-rutinoside) into bitter compound quercetin, contributing significantly to bitterness Tartary buckwheat (Fagopyrum tataricum) (TB). Mitigating this is vital for improving palatability and marketability TB products. In study, we integrated genomic transcriptomic data with molecular docking analyses identify 12 potential rutin-degrading TB. Among them, FtBGLU29 exhibited stable binding affinity...
Tartary buckwheat is highly valued for its abundant rutin (quercetin 3-O-rutinoside). As a flavonoid glycoside, synthesized with the crucial involvement of UDP-dependent glycosyltransferases (UGTs). However, functions and transcriptional regulation UGT-encoded genes remain poorly understood. This study identified key gene, FtUFGT163, potentially encoding flavonol 3-O-glucoside (1 → 6) rhamnosyltransferase in through omics analysis molecular docking methods. The recombinant FtUFGT163...
Flavonoids are known for potent antioxidant activity and antihyperlipidemia. As a result of the few antinutritional factors high bioactive substances, such as flavonoids, sprouts tartary buckwheat (Fagopyrum tataricum, STB) have become healthy food. This study aims to unravel antihyperlipidemic effects STB in vivo its potential mechanism through transcriptomic metabonomic analysis. The physiological parameters mice administered high-fat diet with or without 2.5 5% 10 weeks were recorded....
Tartary buckwheat (TB) is a pseudocereal rich in flavonoids, mainly including flavonols and anthocyanins. The flavonoid 3'-hydroxylase (F3'H) key enzyme biosynthesis encoded by two copies TB genome. However, its biological function effects on flavonol anthocyanin synthesis have not been well validated yet. In this study, we cloned the full-length FtF3'H1 gene highly expressed all tissues (compared with FtF3'H2) according to flowering transcriptome data. corresponding protein contains 534...
Tartary buckwheat (<i>Fagopyrum Tataricum</i>) is a well-known pseudocereal for its health and economic value. However, abundant antinutritional factors (ANFs) reduces benefits. As reported, germination can improve the nutritional profile of grains. In this study, we systematically evaluate safety seeds (TB) sprouts (TBS) used as high active ingredients. After evaluating nutrition levels, bioactive compounds ANFs in TBS during germinating, fifth-day were selected raw material. C57BL/6J mice...
The long non-coding RNA (lncRNA) LINC00514 was identified to play an essential oncogenic function in different human cancers, but its effects non-small cell lung cancer (NSCLC) are yet be elucidated. In this study, we evaluated the of NSCLC. expression and prognosis NSCLC were analyzed using qRT-PCR online bioinformatic tools. bioeffects LINC0514 cells examined counting kit-8, colony formation, transwell assays. Western blotting used measure target proteins. regulation Wnt/β-catenin...
Abstract Drought and high salinity affect plant growth, development, yield, quality. MYB transcription factors (TFs) in plants play an indispensable regulatory role resisting adverse stress. In this study, screening functional validation of the TF FtMYB30, which can respond extensively to abiotic stress abscisic acid (ABA), was achieved Tartary buckwheat. one SG22 (sub‐group 22) family R2R3‐MYB TFs, localized nucleus had transcriptional activation activity. Under drought salt stress, FtMYB30...
<title>Abstract</title> The flavonol biosynthesis branch generates the main flavonoids in Tartary buckwheat (TB), with rutin serving as a representative compound. Flavonol synthase (FLS) is vital enzyme involved this metabolic pathway. Out of five known <italic>FLS</italic> genes TB genome, <italic>FtFLS1</italic> only gene identified, while information about remaining four limited. In study, we cloned FtFLS from and performed molecular identification. results showed that...
Abstract Anthocyanins are important flavonoid compounds that abundant in Tartary buckwheat, providing a variety of bright colors and enhancing abiotic stress resistance. Our study found FtMYB22 specifically affected anthocyanin anabolism. In this study, overexpression the transcription factor tobacco significantly reduced accumulation flavonol petals transgenic plants. Moreover, it downregulated expression genes involved biosynthesis tobacco. Overexpression buckwheat hairy roots inhibited...