A5049685516- Hydrocarbon exploration and reservoir analysis
- Hydraulic Fracturing and Reservoir Analysis
- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Seismic Imaging and Inversion Techniques
- Petroleum Processing and Analysis
- Nutritional Studies and Diet
- Drilling and Well Engineering
- NMR spectroscopy and applications
- Obesity, Physical Activity, Diet
- Physical Activity and Health
- Adipose Tissue and Metabolism
- Body Contouring and Surgery
- Circadian rhythm and melatonin
- Esophageal Cancer Research and Treatment
- Geochemistry and Geologic Mapping
- Diabetes Treatment and Management
- Enhanced Oil Recovery Techniques
- Muscle metabolism and nutrition
- Liver Disease Diagnosis and Treatment
- Esophageal and GI Pathology
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Geophysical and Geoelectrical Methods
- Gastroesophageal reflux and treatments
- Atmospheric and Environmental Gas Dynamics
Inserm
2011-2025
Institut du Thorax
2018-2025
Nantes Université
2019-2025
Centre National de la Recherche Scientifique
2018-2025
Saudi Aramco (United States)
2015-2023
Centre Hospitalier Universitaire de Nantes
2019-2022
Harvard University
2012-2022
Centre de Recherche en Nutrition Humaine Rhône-Alpes
2007-2021
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2021
Centre Hospitalier Universitaire de Tours
2004-2020
Hyperglycemia is a result of impaired insulin action on glucose production and disposal, major target antidiabetic therapies. The study insulin-independent regulatory mechanisms metabolism may identify new strategies to lower blood sugar levels. Here we demonstrate an unexpected metabolic function for IL-13 in the control hepatic production. Th2 cytokine known mediate macrophage alternative activation. Genetic ablation Il-13 mice (Il-13–/–) resulted hyperglycemia, which progressed resistance...
Metabolic pathways and inflammatory processes are under circadian regulation. Rhythmic immune cell recruitment is known to impact infection outcomes, but whether the clock modulates immunometabolism remains unclear. We find that molecular Bmal1 induced by stimulants, including Ifn-γ/lipopolysaccharide (M1) tumor-conditioned medium, maintain mitochondrial metabolism metabolically stressed conditions in mouse macrophages. Upon M1 stimulation, myeloid-specific knockout (M-BKO) renders...
IL-13 hits the gym Interleukin-13 (IL-13) is a cytokine secreted by T cells, innate lymphoid cells (ILC2s), and granulocytes. It acts as central mediator in allergy antihelminth defense with various effects. Knudsen et al. report distinct role for exercise metabolism (see Perspective Correia Ruas). Mice subjected to endurance training showed increases circulating IL-13, which correlated ILC2 expansion muscles. By contrast, exercise-induced muscle fatty acid utilization mitochondrial...
Abstract Gas shales are economically viable hydrocarbon prospects that have proven to be successful in North America. Unlike conventional prospects, gas serve as the source, seal, and reservoir rock. Generating commercial production from these unique lithofacies requires stimulation through extensive hydraulic fracturing. The absence of an accurate petrophysical model for unconventional plays makes prediction economic productivity fracturing success risky. This paper presents integrated...
Background Physical activity is a major component of healthy lifestyle in youth and adults. To identify determinants this complex behavior an important research objective the process designing interventions to promote physical at population level. In addition individual determinants, there evidence documenting familial influences on activity. However, few studies that have addressed issue with measures did not provide data parent-offspring relationships throughout childhood adolescence. The...
Nonalcoholic fatty liver disease (NAFLD) is a dysmetabolic hepatic damage of increasing severity: simple fat accumulation (steatosis), nonalcoholic steatohepatitis (NASH), and fibrosis. Oxidative stress considered an important factor in producing hepatocyte injury associated with NAFLD progression. Studies also suggest link between the specific lipid species, mitochondrial dysfunction, progression NAFLD. However, it unclear whether modifications are involved To gain insight into relationship...
Summary Carbonate rocks are complex in structure and pore geometry display heterogeneity on all length scales. In this paper, carbonate described the basis of their contents for use pore-scale modeling. Definitions grains porosities based other carbonate-rock classifications; we did not invent new concepts. On content (grain, mud, cement), were divided into three types: muddy, grainy, mixed. Each type was subtypes geometries defined by researchers. Pore-size distribution Lønøy (2006) used...
Background: Increasing physical activity and decreasing sedentary time are cornerstones in the management of type 2 diabetes (T2DM). However, there few instruments available to measure this population. We translated long version International Physical Activity Questionnaire (IPAQ-L) into French studied its reproducibility validity patients with T2DM. Methods: Reproducibility was by telephone administrations, 8 days apart. Concurrent tested against pedometry for 7 during habitual life....
Oil and gas production from shale formations has proven to be economical because of advances in hydraulic fracturing but remains very challenging part the presence ductile, polymer nature hydrocarbon source material, kerogen. This organic matter is intertwined among silicates, aluminosilicates, other minerals as fine laminae that weave rock fabric, adding soft mechanical cohesion material. A potential solution been developed, a new type reactive fluid composed strong oxidizers such bromate...
To compare cognitive impairments in dementia with Lewy bodies (DLB) and Parkinson's disease (PDD), to discriminate between the two entities.10 DLB 12 PDD consecutive patients performed a neuropsychological battery designed assess several domains: verbal visual memory (Delayed Matching Sample (DMS)-48), language, gnosia, praxia executive functions.DLB had poorer performances orientation (p<0.05), Trail Making Test A (p<0.05) reading of names colours Stroop (p<0.05). Their scores were also...
Abstract A new openhole logging service, RockViewSM, has been developed which provides lithological and quantitative mineralogical information for accurate formation evaluation. The assessment begins with elemental weights follows an interpretation of lithology mineralogy. Lithologies are divided into general categories including sand, shale, coal, carbonates, evaporites. Potentially identifiable minerals quartz, potassium-feldspar, albite, calcite, dolomite, siderite, anhydrite,...
Abstract Objective: The objective was to evaluate two accelerometers, the RT3 and TriTrac‐R3D for their ability produce estimates of physical activity‐related energy expenditure (PAEE) in overweight/obese adults. Research Methods Procedures: PAEE from both accelerometers were obtained experiments. In Experiment 1, 13 subjects (BMI 34.2 ± 6.4 kg/m 2 ) monitored over weeks everyday life, being simultaneously measured by doubly labeled water method (DLW). 2, 8 34.3 5.0 10 normal‐weight 20.8 2.1...
Abstract The successful recovery of hydrocarbons from gas shales requires a fundamental understanding the reservoir's rock-matrix properties. Information about variable lithologies, mineralogies, and kerogen content is vital to locate favorable intervals for production. Knowledge in-situ stresses porosity these essential developing hydraulic fracturing strategies recover in place. Often properties are established analysis cores extracted wellbore, time-consuming practice which causes costly...