Wan Gao

ORCID: 0000-0001-8688-2590
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Research Areas
  • Synthesis of Organic Compounds
  • Natural Compound Pharmacology Studies
  • Bioactive natural compounds
  • Phytochemistry and Bioactive Compounds
  • Carbohydrate Chemistry and Synthesis
  • Advanced biosensing and bioanalysis techniques
  • Phytochemistry and Biological Activities
  • DNA and Nucleic Acid Chemistry
  • Phytochemical Studies and Bioactivities
  • Natural Antidiabetic Agents Studies
  • DNA and Biological Computing
  • Industrial Gas Emission Control
  • Catalytic Cross-Coupling Reactions
  • Advances in Cucurbitaceae Research
  • Gestational Diabetes Research and Management
  • Diabetes Management and Research
  • Phytochemicals and Antioxidant Activities
  • Catalytic C–H Functionalization Methods
  • Biological and pharmacological studies of plants
  • Animal Nutrition and Physiology
  • Diabetes Treatment and Management
  • Bioactive Compounds and Antitumor Agents
  • Antioxidant Activity and Oxidative Stress
  • Oxidative Organic Chemistry Reactions
  • Traditional and Medicinal Uses of Annonaceae

First Hospital of Xi'an
2024

Xian Central Hospital
2024

Dongguan University of Technology
2022

Guangdong University of Technology
2022

Chinese Academy of Medical Sciences & Peking Union Medical College
2011-2019

Peking Union Medical College Hospital
2019

Xinjiang Institute of Materia Medica
2019

Nanchang University
2014-2015

Twenty polycyclic polyprenylated acylphloroglucinols (PPAPs), including the new compounds hyperscabrones A–I (1–9), were isolated from air-dried aerial parts of Hypericum scabrum. These comprise seven different structural types. All structures determined by NMR spectroscopic methods and both experimental calculated electronic circular dichroism (ECD) spectra. The evaluation their neuroprotective effects on glutamate-induced toxicity in SK-N-SH cells showed that 4–7 exhibited significant...

10.1021/acs.jnatprod.5b01063 article EN Journal of Natural Products 2016-06-09

A horseradish peroxidase (HRP)-mimicking DNAzyme sequence is first blocked by the triplex-based molecular beacon (tMB). Upon hybridization with single-stranded DNA inputs, triplex–helix switch occurs, and released product strand self-assembles into hemin/G-quadruplex-HRP-mimicking that biocatalyzes formation of a colored provides an output signal for different logic gates. On basis this principle, series gates (OR, XOR, INHIBIT, AND) have been developed. Moreover, multilevel circuit (MC)...

10.1021/jp503608t article EN The Journal of Physical Chemistry C 2014-06-10

1. A total of 360 1-d-old male commercial Arbor Acre broiler chickens were randomly assigned to 5 groups (6 replicates 12 birds each) evaluate the dietary effects polysavone (0·5, 1·0 and 1·5 g/kg), a natural extract from alfalfa, 0·15 g/kg chlortetracycline (CTC) on growth performance, antioxidation meat quality chickens. 2. Over 6-week study, feed intake increased significantly with CTC supplementation final body weight (BW) was higher for treatments. Feed:gain ratio not affected by 3. At...

10.1080/00071668.2011.569008 article EN British Poultry Science 2011-06-01

Abstract The logic system is obtained by using a series of double‐stranded (ds) DNA templates with mismatched base pairs (T–T or C–C) and ion‐modulated exonuclease III (Exo III) activity, in which the Exo cofactors, Hg 2+ Ag + ions, are used as inputs for activation respective scission based on formation T–Hg –T C–Ag –C pairs. Additionally, two kinds signal probes utilized to transduce operations. One split G‐rich strands that design OR, AND, INHIBIT, XOR gates, whereas other self‐assembled...

10.1002/chem.201502122 article EN Chemistry - A European Journal 2015-09-02

Two new bidesmoside triterpenoid saponins which were identifed as 28-O-β-D-xylopyranosyl(1→3)-β-D-xylopyranosyl(1→4)-α-L-rhamnopyranosyl(1→2)-[α-L-rhamno-pyranosyl(1→3)]-β-D-fucopyranosyl gypsogenin 3-O-β-D-glucopyranosyl (1→2)-β-D-glucopyranosiduronic acid (C1) and 28-O-β-D-xylopyranosyl(1→4)-α-L-rhamnopyranosyl (1→2)-[α-L-rhamnopyranosyl(1→3)]-β-D-fucopyranosyl 3-O-β-D-gluco-pyranosyl(1→2)-β-D-glucopyranosiduronic (C2) isolated together with two known compounds from the seeds of Momordica...

10.3390/molecules19022238 article EN cc-by Molecules 2014-02-21

Two new cucurbitane triterpenoids 1 and 2 were isolated, together with six known compounds, from the seeds of Momordica charantia L. The structures compounds determined to be 3-O-{[β-d-galactopyranosyl(1 → 6)]-O-β-d-galactopyranosyl}-23(R), 24(R), 25-trihydroxycucur-bit-5-ene (1), 3-O-[β-d-galactopyranosyl]-25-O-β-d-galactopyranosyl-7(R), 22(S), 23(R), 25-pentahydroxycucurbit-5-ene (2), respectively. Their elucidated by combination mass spectrometry, one- two-dimensional NMR experiments...

10.1080/10286020.2014.914502 article EN Journal of Asian Natural Products Research 2014-04-29

Saffloneoside (<bold>1</bold>), a structurally unusual <italic>p</italic>-hydroxycinnamylcyclopentenone <italic>C</italic>-glucoside obtained from the florets of <italic>Carthamus tinctorius</italic>, was synthesized on gram scale in seven steps.

10.1039/c9qo00279k article EN Organic Chemistry Frontiers 2019-01-01

BACKGROUND Insulin injection is the basic daily drug treatment for diabetic patients. AIM To evaluate comparative impacts of continuous subcutaneous insulin infusion (CSII). METHODS Based on modality received, patients were allocated into two cohorts: The CSII group and multiple injections (MDI) group, with each cohort comprising 210 Comparative assessments made regarding serum levels serum-secreted frizzled-related protein 5, homocysteine, C1q/TNF-related 9. Furthermore, outcomes such as...

10.12998/wjcc.v12.i18.3378 article EN World Journal of Clinical Cases 2024-06-18

Herein, the spectral data, including nuclear magnetic resonance spectroscopy (NMR) and mass gas chromatography data of eight cholestane glycosides from Ornithogalum saundersiae Baker (Asparagaceae) bulbs are described. The linked with article entitled "Structure bioactivity Baker" (Chen et al., 2019).

10.1016/j.dib.2019.104391 article EN cc-by Data in Brief 2019-08-13

The authors proposed a new class of highly efficient and easily adjustable ligands for Pd-catalyzed amination Suzuki cross-coupling reactions. are prepared in two synthetic steps from readily available precursors. This approach allows to synthesize the combinatorial way order adjust their catalytic activity given reaction. these catalysts Suzuki-Miyaura aryl chlorides is comparable with best known date

10.1055/s-2006-941879 article EN Synfacts 2006-06-01

Antibiotics are a class of organic pollutant in the medical field for hundreds years. Due to continuous discharge antibiotics environment, phenomenon pseudo-persistence is produced. Therefore, it necessary develop an advanced sustainable technology remove from water resources. In this study, Zeolite Imidazole Framework-8 (ZIF-8) was prepared by simple and rapid method. Oxytetracycline (OTC) degradation performed using ZIF-8 as photocatalyst under visible light (VL) (500[Formula: see text]W...

10.1142/s1793292022500424 article EN NANO 2022-05-11
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