Zheng-Yi Gu

ORCID: 0000-0001-7363-2269
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Research Areas
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Synthesis of Organic Compounds
  • Pomegranate: compositions and health benefits
  • Pharmacological Effects of Natural Compounds
  • Natural product bioactivities and synthesis
  • Advanced Topics in Algebra
  • Drug-Induced Hepatotoxicity and Protection
  • Computational Drug Discovery Methods
  • Wound Healing and Treatments
  • Cellular Automata and Applications
  • Phytochemicals and Antioxidant Activities
  • Contact Dermatitis and Allergies
  • Bioactive Compounds in Plants
  • Advances in Cucurbitaceae Research
  • Inflammatory mediators and NSAID effects
  • Neuroendocrine regulation and behavior
  • Biological Activity of Diterpenoids and Biflavonoids
  • Natural Compound Pharmacology Studies
  • Veterinary Pharmacology and Anesthesia
  • Phytochemistry and Biological Activities
  • Crystal structures of chemical compounds
  • Synthesis and biological activity
  • Chromatography in Natural Products
  • Allergic Rhinitis and Sensitization

Xinjiang Institute of Materia Medica
2009-2023

Xinjiang Medical University
2021-2023

Xinjiang Uygur Autonomous Region Disease Prevention and Control Center
2013

First Affiliated Hospital of Shihezi University Medical College
2013

First Affiliated Hospital of Chengdu Medical College
2013

Chengdu Medical College
2013

Background Pomegranate ( punica granatum ) belongs to the family Punicaceae, and its peel has been used as a traditional Chinese medicine because of efficacy in restraining intestine, promoting hemostasis, killing parasites. reported possess wound-healing properties which are mainly attributed polyphenol extracts. The purpose this study was investigate effect pomegranate polyphenols (PPP) gel on cutaneous wound healing diabetic rats. Methods Alloxan-induced rats were given incisional wounds...

10.3760/cma.j.issn.0366-6999.20122728 article EN cc-by-nc-nd Chinese Medical Journal 2013-05-05

Nymphaea candida is traditional Uighur medicine that commonly used to treat head pains, cough, hepatitis and hypertension in Xinjiang of China. In this article, the extract N. was measured for antioxidant activity, using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals scavenging assay reducing power determination, compared with those positive controls butylated hydroxytoluene (BHT) gallic acid (GA). The active further purified by liquid-liquid partition afford four fractions, which ethyl...

10.1093/ecam/nep003 article EN cc-by Evidence-based Complementary and Alternative Medicine 2009-02-07

Twigs and leaves of Juniperus sabina L. have been traditionally used as the medicinal herb in China for treatment many ailments including rheumatoid arthritis (RA).To confirm therapeutic effect total flavonoids from J. (JSTF) on RA-induced by Complete Freund's Adjuvant (CFA) rats.Wistar rats (200 ± 20 g) were immunized intradermal injection 0.1 mL CFA into right hind metatarsal footpad. JSTF was administered orally at dose 125,250 500 mg/kg 14 days after induction adjuvant arthritis....

10.4103/0973-1296.186346 article EN Pharmacognosy Magazine 2016-01-01

Artemitin, a significant flavonol compound existing in Laggera pterodonta (DC.) Benth., Artemisia rupestris L, etc., is the subject of attention by researchers owing to its pharmacological activities (such as antioxidative, anti-inflammatory and antiviral). In this work, highly sensitive specific high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS) assay combined with protein precipitation has been established validated for determining...

10.1002/bmc.4356 article EN Biomedical Chromatography 2018-08-07

Hyssopus cuspidatus Boriss. (Shen Xiang Cao (SXC)), a traditional medicine herb in Xinjiang, has long history of being used by minorities to treat asthma. However, its active antiasthmatic compounds and underlying mechanism action are still unknown. The aim this study was investigate the bioactive explore molecular SCX treatment asthma using network pharmacology.The were collected literature search, Traditional Chinese Medicine Systems Pharmacology Database Analysis Platform (TCMSP)...

10.1155/2021/7671247 article EN Evidence-based Complementary and Alternative Medicine 2021-11-29

Abstract: Aim: To investigate the anti-inflammatory activity of punicalagin (PUN) on mouse macrophages and underlying mechanisms. Materials Methods: Mouse primary peritoneal (PMs) were treated with lipopolysaccharide (LPS; 10μg/ml) and/ or PUN (50μM) for 4, 8 12 hr. The expression levels inducible nitric oxide synthase (iNOS), interleukin (IL)-1β, IL-6, IL-12P40 CCL-2 mRNAs analyzed by qRT-PCR. Total iNOS, MAPK JAK/STAT protein measured Western blotting secreted IL-1β, IL-1270 ELISA. Acute...

10.5530/ijper.55.2.93 article EN cc-by-nc-nd Indian Journal of Pharmaceutical Education and Research 2021-05-17

The title compound, C(22)H(26)O(9), crystallizes with two independent mol-ecules in the asymmetric unit which dihedral angles between benzene rings are 21.4 (2) and 5.1 (2)°. An intra-molecular O-H⋯O hydrogen bond occurs each mol-ecule. Inter-molecular C-H⋯O bonds stabilize crystal structure.

10.1107/s1600536811041213 article EN cc-by Acta Crystallographica Section E Structure Reports Online 2011-10-12
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