Huan Yan

ORCID: 0009-0008-1810-4920
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About
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Research Areas
  • Natural product bioactivities and synthesis
  • Cancer Research and Treatments
  • Hippo pathway signaling and YAP/TAZ
  • Speech and Audio Processing
  • Chromium effects and bioremediation
  • Phytochemistry and Biological Activities
  • Hepatitis B Virus Studies
  • Railway Engineering and Dynamics
  • Indoor and Outdoor Localization Technologies
  • Pharmacological Effects of Natural Compounds
  • Mechanical stress and fatigue analysis
  • RNA Interference and Gene Delivery
  • Structural Engineering and Vibration Analysis
  • Inflammasome and immune disorders
  • Fluid Dynamics and Heat Transfer
  • Energy, Environment, Economic Growth
  • Insect and Arachnid Ecology and Behavior
  • Structural Health Monitoring Techniques
  • Image Processing Techniques and Applications
  • Non-Destructive Testing Techniques
  • Peptidase Inhibition and Analysis
  • Cancer Cells and Metastasis
  • Extracellular vesicles in disease
  • Advancements in Battery Materials
  • Chromatography in Natural Products

Affiliated Hospital of Jining Medical University
2025

Guizhou Normal University
2024-2025

Chengdu Women's and Children's Central Hospital
2022-2025

Southeast University
2023-2024

Hefei University of Technology
2024

Guangzhou Experimental Station
2024

Chinese Academy of Sciences
2024

First Affiliated Hospital of Zhengzhou University
2024

Hunan University of Traditional Chinese Medicine
2022-2024

Zhejiang Sci-Tech University
2024

Abstract Damage to solid polymer electrolytes can lead mechanical degradation, short circuits, or functional failures. Therefore, introducing a self‐healing function is an ideal strategy improve the safety and reliability of electrolyte systems. Herein, dynamic boronic ester‐based (DB‐SHPEs) with excellent properties interfacial stability are developed via thermally initiated ring‐opening reaction between thiol epoxy groups. The DB‐SHPEs containing ester bonds not only alter topologies...

10.1002/adfm.202212005 article EN Advanced Functional Materials 2023-01-15

Excessive and unresolved neuroinflammation is a key component of the pathological cascade in brain injuries such as ischemic stroke. Here, we report that TRIM9, brain-specific tripartite motif (TRIM) protein, was highly expressed peri-infarct areas shortly after insults mice, but expression decreased aged which are known to have increased Mechanistically, TRIM9 sequestered β-transducin repeat-containing protein (β-TrCP) from Skp-Cullin-F-box ubiquitin ligase complex, blocking IκBα...

10.1016/j.celrep.2018.12.055 article EN cc-by-nc-nd Cell Reports 2019-04-01

Green innovation is one of the most important approaches to prevent environmental pollution and foster sustainable development. Embedded in global production networks, manufacturing firms have been found not only be main drivers but also polluters developing countries. However, relatively few studies systematically considered effect value chain (GVC) participation on green context By using a panel dataset Chinese listed firms, this study conducts data fixed-effect analyses uses instrumental...

10.3390/ijerph19148403 article EN International Journal of Environmental Research and Public Health 2022-07-09

Background Pomegranate ( punica granatum ) belongs to the family Punicaceae, and its peel has been used as a traditional Chinese medicine because of efficacy in restraining intestine, promoting hemostasis, killing parasites. reported possess wound-healing properties which are mainly attributed polyphenol extracts. The purpose this study was investigate effect pomegranate polyphenols (PPP) gel on cutaneous wound healing diabetic rats. Methods Alloxan-induced rats were given incisional wounds...

10.3760/cma.j.issn.0366-6999.20122728 article EN cc-by-nc-nd Chinese Medical Journal 2013-05-05

The clinical pictures of essential tremor (ET) and Parkinson's disease (PD) are often quite mimic at the early stage, longstanding ET may ultimately develop to PD, that is, PD with "antecedent ET". Early diagnosis differentiation two for predicting progression formulating individualized treatment plans. However, current approaches remain challenging. This study aimed determining morphological, microstructural iron-related changes in these patients' brains using multimodal magnetic resonance...

10.2147/ndt.s498644 article EN cc-by-nc Neuropsychiatric Disease and Treatment 2025-01-01

Cable force estimation of the suspenders is tremendous significance for safety and condition evaluation arch bridges. The modern suspender cable structure widely used nowadays calls an efficient robust method accounting bending stiffness, complex boundary conditions, intermediate dampers, variable segments. To estimate tension in bridge suspenders, this paper proposes exact analytical that can simultaneously consider aforementioned factors first time. Based on a generalized model including...

10.1061/jbenf2.beeng-6594 article EN Journal of Bridge Engineering 2024-04-05

The creation of safe and effective vaccines that induce potent cellular humoral immune responses against SARS-CoV-2 is urgently needed to end the global COVID-19 epidemic. Here, we developed an alphavirus-derived self-replicating RNA (repRNA)-based vaccine platform encoding receptor-binding domain (RBD) spike glycoprotein. repRNA triggers prolonged antigen expression compared with conventional mRNA due replication machinery repRNA. To improve delivery efficacy repRNA, a self-assembling...

10.1016/j.omtn.2023.04.021 article EN cc-by-nc-nd Molecular Therapy — Nucleic Acids 2023-04-23

Pregabalin is the first-line treatment for neuropathic pain. Cases of cutaneous hypersensitivity reactions caused by pregabalin generally occur within 2 weeks initiating medication. We report a rare case delayed reaction pregabalin, which was confirmed drug provocation test. A 72-year-old man with severe herpes zoster neuralgia developed maculopapular eruption covering 80% to 90% his total body surface area after 40 days combined multidrug analgesia. test positive. The time interval between...

10.1177/03000605241245004 article EN cc-by-nc Journal of International Medical Research 2024-04-01

Spatially resolved transcriptomics (SRT) technologies facilitate gene expression profiling with spatial resolution in a naïve state. Nevertheless, current SRT exhibit limitations, manifesting as either low transcript detection sensitivity or restricted throughput. These constraints result diminished precision and coverage measurement. In response, we introduce SpaGDA, sophisticated deep learning-based graph domain adaptation framework for both scenarios of imputation cell type identification...

10.1093/bib/bbae576 article EN cc-by-nc Briefings in Bioinformatics 2024-09-23

Closely spaced modes commonly observed in long-span suspension bridges can greatly increase the difficulty of identifying and tracking modal parameters. Most existing studies generally focus on closely quantifying uncertainties based numerical experimental models. Further research focusing full-scale is still required. A case study Qixiashan Yangtze River Bridge, a bridge with main span 1 418 m, conducted this paper. The effectiveness generalized fast Bayesian Fourier transform (GFBFFT)...

10.1142/s0219455423501948 article EN International Journal of Structural Stability and Dynamics 2023-03-09

The hangers represent the crucial load-bearing component of arch bridges and are susceptible to dynamic vehicle load. However, little effort has been made carry out analysis bridge under high-speed train loads. This paper presents an investigation behavior subjected with emphasis on flexible hangers, using train–bridge interaction simulation field measurement data. Coupled system model composed three-dimensional model, wheel–rail is established account for hanger transverse vibration,...

10.1142/s0219455425410019 article EN International Journal of Structural Stability and Dynamics 2024-05-08

In this study, we develop a numerical model of two-phase flow with series different contact angles θ based on real feature structures from scanning electron microscopy. Meanwhile, the interface dynamics during Haines jump are analyzed typical pore throat system. We found that under wetting conditions, fluid displacement patterns can be regarded as minimum pressure drop state for completion constant task. Moreover, event is no longer an unfavorable energy leads to rapid dissipation but...

10.1063/5.0132539 article EN Physics of Fluids 2022-12-16
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