A5026139720- Colorectal Cancer Surgical Treatments
- Microplastics and Plastic Pollution
- Folate and B Vitamins Research
- Blockchain Technology Applications and Security
- Advanced ceramic materials synthesis
- Colorectal and Anal Carcinomas
- Immune cells in cancer
- Nitric Oxide and Endothelin Effects
- Recycling and Waste Management Techniques
- Advanced Nanomaterials in Catalysis
- Atherosclerosis and Cardiovascular Diseases
- Gut microbiota and health
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- biodegradable polymer synthesis and properties
- Plant Physiology and Cultivation Studies
- Respiratory viral infections research
- Nanoplatforms for cancer theranostics
- Surgical Simulation and Training
- Aluminum Alloys Composites Properties
- Genetic Neurodegenerative Diseases
- Cassava research and cyanide
- Cell Adhesion Molecules Research
- Ferroptosis and cancer prognosis
- Quantum Dots Synthesis And Properties
- Pediatric health and respiratory diseases
Shandong University of Traditional Chinese Medicine
2023-2025
Xi'an Jiaotong University
2013-2025
Affiliated Hospital of Jining Medical University
2022-2025
Chongqing University
2023-2025
Jiangsu University of Science and Technology
2024-2025
Harbin Institute of Technology
2020-2024
Huazhong University of Science and Technology
2024
Northwest A&F University
2024
First Affiliated Hospital of Xi'an Jiaotong University
2022-2024
Northeastern University
2022-2024
Abstract Appendectomy impacts the homeostasis of gut microbiome in patients. We aimed to study role appendectomy colorectal cancer (CRC) risk through causing microbial dysbiosis. Population-based longitudinal (cohort 1, n = 129,155) showed a 73.0% increase CRC among cases throughout 20 years follow-up (Adjusted sub-distribution hazard ratio (SHR) 1.73, 95% CI 1.49–2.01, P < 0.001). Shotgun metagenomic sequencing was performed on fecal samples from cohort 2 ( 314). Gut dysbiosis subjects...
MicroRNAs (miRNAs) are small, noncoding RNAs that believed to play fundamental roles in tumorigenesis and tumor development at the posttranscriptional level, as negative regulators of gene expression. This study was designed evaluate expression anticancer effect miR-519d ovarian cancer.The levels cancer cells tissues were detected by TaqMan quantitative reverse transcriptase-polymerase chain reaction (TaqMan qRT-PCR; Life Technologies, Carlsbad, CA, USA). The effects on cell proliferation...
Visible-light-induced selective transfer hydrogenation of aromatic aldehyde to the corresponding alcohol was achieved by using Pd nanocatalyst supported on amine-functionalized iron-based metal–organic frameworks [Pd/MIL-101(Fe)-NH2] with triethylamine (TEA) as an electron donor and HCOOH a proton source. The Pd/MIL-101(Fe)-NH2, obtained in situ photodeposition method, showed homogeneously highly dispersed nanoparticles (NPs) uniform size throughout MIL-101(Fe)-NH2 support due effective...
Abstract Background Lateral lymph node dissection (LLND) represents a technically challenging procedure. This study aimed to evaluate the perioperative, genitourinary functional and mid-term oncological outcomes of laparoscopic lateral (LLLND) robotic (RLLND) for advanced lower rectal cancer (ALRC). Methods Between January 2015 April 2021, consecutive patients who underwent RLLND LLLND at two high-volume centres were enrolled. The perioperative outcomes, function recovery compared. A...
Abstract Background Many patients experience anorectal dysfunction after rectal surgery, which is known as low anterior resection syndrome (LARS). Robotic systems have many technical advantages that may be suitable for functional preservation resection. Thus, the study aimed to explore whether robotic surgery can reduce incidence and severity of LARS. Methods Patients undergoing minimally invasive sphincter-sparing cancer were enrolled between January 2015 December 2020. The divided into or...
Abstract Synthetic binding proteins (SBPs) represent a pivotal class of artificially engineered proteins, meticulously crafted to exhibit targeted properties and specific functions. Here, the SYNBIP database, comprehensive resource for SBPs, has been significantly updated. These enhancements include (i) featuring 3D structures 899 SBP–target complexes illustrate epitopes (ii) using SBPs in monomer or complex forms with target their sequence space expanded five times 12 025 by integrating...
In this study, a novel 1/3-scale water model was designed for 160-ton ladle based on the similarity principle. The consists of 24 bottom blow holes and four measuring electrodes positioned at various directions heights. order to determine optimal layout double-nozzle blowing global level, fully combined experiments were conducted radial positions 0.55R, 0.60R, 0.65R 0.70R five angles 90°, 95°, 100°, 110° 120°. By investigating effects different combinations position flow rate mixing time,...
The rare metal element molybdenum functions as a cofactor in molybdoenzymes that are essential to life almost all living things. Molybdate can be captured by the periplasmic substrate-binding protein ModA of ModABC transport system bacteria. We demonstrate plays crucial roles growth, multiple metabolic pathways, and ROS tolerance Acinetobacter baumannii . Crystal structures molybdate-coordinated A. show noncanonical disulfide bond with conformational change between reduced oxidized states....
The clinical pictures of essential tremor (ET) and Parkinson's disease (PD) are often quite mimic at the early stage, longstanding ET may ultimately develop to PD, that is, PD with "antecedent ET". Early diagnosis differentiation two for predicting progression formulating individualized treatment plans. However, current approaches remain challenging. This study aimed determining morphological, microstructural iron-related changes in these patients' brains using multimodal magnetic resonance...
Objective— MED1 (mediator 1) interacts with transcription factors to regulate transcriptional machinery. The role of in macrophage biology and the relevant disease state remains be investigated. Approach Results— To study molecular mechanism by which regulates M1/M2 phenotype switch effect on atherosclerosis, we generated MED1/apolipoprotein E (ApoE) double-deficient (MED1 ΔMac /ApoE − /− ) mice found that atherosclerosis was greater −/− than fl/fl littermates. gene expression M1 markers...
Abstract Background We analyzed the clinical characteristics of children with plastic bronchitis (PB) caused by Mycoplasma pneumoniae (MP) and explored its risk factors. Methods prospectively data MP pneumonia (MPP) treated fiberoptic bronchoscopy (FB). Patients were classified into a PB non-PB group. General information, manifestations, laboratory tests, results computed tomography scan, FB findings compared between groups. conducted statistical analysis factors for developing PB. Results...
This study investigates the relationship between urban block spatial morphology and microclimate in severe cold regions, using Shenyang, China as a case study. We employed computational fluid dynamics theory-based numerical simulation software controlled variable approach to analyze effects of four key aspects: street conforming line ratio, interface density, aspect building roof forms. The primary findings are follows: Decreasing ratios initially increase average wind speed temperature....
Abstract Drylands play an essential role in Earth’s environment and human systems. Although dryland expansion has been widely investigated previous studies, there is a lack of quantitative evidence supporting human-induced changes extent. Here, using multiple observational datasets model simulations from phase 6 the Coupled Model Intercomparison Project, we employ both correlation-based optimal fingerprinting approaches to conduct detection attribution expansion. Our results show that...
Disorders of the central nervous system (CNS) constitute a significant global health concern at moment. Most CNS disorders are characterized by severe neuronal damage with excessive production reactive oxygen species, which induces high levels oxidative stress and intense inflammatory responses in affected tissues, thus aggravating disease pathology. Notably, blood–brain barrier makes it difficult to deliver many drugs biologics CNS, creates great difficulties diagnosis treatment disorders....
Controlling filler localization is essential, yet not easy, when building a synergistic 3D conductive network of fillers with different sizes and shapes in multiphase polymer blends. We herein report on preparing composites double-percolated structures controlled from an immiscible blend poly(ethylene-co-octene) (POE) poly(butylene adipate-co-terephthalate) (PBAT). The 2D microscale graphite flakes (FGs) exhibit distinct dispersion behaviors their 1D nanoscale analogue, carbon nanotubes...