A5101986830- Animal Virus Infections Studies
- Virus-based gene therapy research
- Influenza Virus Research Studies
- Respiratory viral infections research
- Parvovirus B19 Infection Studies
- Viral gastroenteritis research and epidemiology
- Animal Disease Management and Epidemiology
- Advanced Photocatalysis Techniques
- Advanced Nanomaterials in Catalysis
- Concrete and Cement Materials Research
- Micro and Nano Robotics
- Magnesium Oxide Properties and Applications
- Gas Sensing Nanomaterials and Sensors
- Neurological disorders and treatments
- Nanoplatforms for cancer theranostics
- Catalytic Processes in Materials Science
- interferon and immune responses
- Molecular Communication and Nanonetworks
- Advanced oxidation water treatment
- Conducting polymers and applications
- Parkinson's Disease Mechanisms and Treatments
- Environmental remediation with nanomaterials
- International Law and Aviation
- Wood and Agarwood Research
- Extracellular vesicles in disease
Shandong University
2024-2025
Jining Medical University
2025
South China Agricultural University
2018-2025
Guangxi University
2023-2024
Nanjing Normal University
2023-2024
Georgia Institute of Technology
2024
Shenzhen Institute of Neuroscience
2024
Ministry of Agriculture and Rural Affairs
2023
Wuhan University of Technology
2022-2023
University of Hong Kong - Shenzhen Hospital
2023
Aim: To analyze the expression profiles, clinicopathological features and chemotherapeutic efficacies of exosome-derived miRNAs in diffuse large B-cell lymphoma (DLBCL). Materials & methods: Next-generation sequencing technique was performed to identify miRNA profiles exosomes from parental chemoresistant DLBCL cells. The results were validated by quantitative real-time PCR, further analyzed bioinformatics statistical methods. Results: We identified 37 significantly upregulated 17...
Recombinant granulocyte colony-stimulating factor (G-CSF), with a direct repair effect on injured cardiomyocytes against myocardial infarction ischemia-reperfusion-injury (IRI), displays poor owing to the limited cardiac targeting efficacy. There are almost no reports of nanomaterials that deliver G-CSF IRI site. Herein, we propose way protect by constructing one layer nitric oxide (NO)/hydrogen sulfide (H2S) nanomotors its outside. NO/H2S specific chemotactic ability high expression...
Zinc-α2-glycoprotein (ZAG, also listed as AZGP1 in the MGI Database), a lipid-mobilising factor, has recently been suggested potential candidate modulation of body weight. We investigated effect increased adiposity on ZAG expression adipose tissue and liver plasma levels obese ( ob/ob ) mice compared with lean siblings. The study examined pro-inflammatory cytokine tumour necrosis factor-α (TNFα) adipocytes. Zag mRNA were significantly reduced subcutaneous (fourfold) epididymal (eightfold)...
Canine parvovirus (CPV-2) is one of the most important pathogens in dogs, and despite continual development vaccines against CPV-2, CPV-2 still circulating canine population. The CPV-2a/2b/2c variant has replaced original virus seems to exhibit accelerated transmission. Although infection been frequently reported, no studies have summarized information variants currently worldwide. To track evolution we downloaded analyzed all VP2 sequences from NCBI database (from 1978 2022). We found that...
Chrysanthemum Fusarium wilt is a soil-borne disease that causes serious economic losses to the chrysanthemum industry. However, molecular mechanism underlying response of WRKY oxysporum infection remains largely unknown. In this study, we isolated CmWRKY6-1 from 'Jinba' and identified it as transcriptional repressor localized in nucleus via subcellular localization activation assays. We found negatively regulated resistance F. affected reactive oxygen species (ROS) salicylic acid (SA)...
Canine circovirus (CanineCV) is an emerging virus in canines. Since the first strain of CanineCV was reported 2012, infection has shown a trend toward becoming global epidemic. often occurs with coinfection other pathogens that may aggravate symptoms disease affected dogs. Currently, not been successfully isolated by laboratories, resulting lack clarity regarding its physicochemical properties, replication process, and pathogenic characteristics. To address this knowledge gap, following...
The clinical pictures of essential tremor (ET) and Parkinson's disease (PD) are often quite mimic at the early stage, longstanding ET may ultimately develop to PD, that is, PD with "antecedent ET". Early diagnosis differentiation two for predicting progression formulating individualized treatment plans. However, current approaches remain challenging. This study aimed determining morphological, microstructural iron-related changes in these patients' brains using multimodal magnetic resonance...
ABSTRACT As companion animals, dogs are susceptible to various subtypes of influenza A virus (IAV), with the H3N2 and H3N8 canine (CIV) stably circulating among canines. Compared CIV, CIV is more widely prevalent in populations demonstrates increased adaptability mammals, potentially facilitating cross-species transmission. Therefore, a comprehensive elucidation mechanisms underlying adaptation mammals imperative. In this study, we serially passaged GD14-WT strain murine lungs, successfully...
Viral respiratory and intestinal infections are the most common causes of canine viral illness. Infection with multiple pathogens occurs in many cases. Rapid diagnosis these is important for providing timely effective treatment. To improve diagnosis, this study, two new multiplex polymerase chain reactions (mPCRs) were developed simultaneous detection viruses (CRV) enteric (CEV) using separate primer mixes. The included adenovirus type 2 (CAV-2), distemper virus (CDV), influenza (CIV),...
Canine parvovirus type 2 (CPV-2), a serious pathogen, leads to high morbidity and mortality in dogs several wild carnivore species. Although it is DNA virus, evolves particularly rapidly, with genomic substitution rate of approximately 10-4 substitutions/site/year, close that some RNA viruses. Tracing the prevalence CPV-2 significant.In this study, an aetiological survey was carried out from 2016 2019 Guangdong Province, China, involving Guangzhou, Shenzhen Dongguan. Furthermore,...
Disorders of the central nervous system (CNS) constitute a significant global health concern at moment. Most CNS disorders are characterized by severe neuronal damage with excessive production reactive oxygen species, which induces high levels oxidative stress and intense inflammatory responses in affected tissues, thus aggravating disease pathology. Notably, blood–brain barrier makes it difficult to deliver many drugs biologics CNS, creates great difficulties diagnosis treatment disorders....
Organic hole transport layers (HTLs) have been known to be susceptible thermal stress, leading poor long-term stability in perovskite solar cells (PSCs). We synthesized three 2,5-dialkoxy-substituted, 1,4-bis(2-thienyl)phenylene (TPT)-based conjugated polymers (CPs) linked with thiophene-based (thiophene (T) and thienothiophene (TT)) comonomers evaluated them as HTLs n-i-p PSCs. TPT-T (MB/C6), which has branched 2-methylbutyl linear hexyl (MB/C6) side chains, emerged a promising HTL...
Canine parvovirus type 2 (CPV-2) is a member of the Parvoviridae family, characterized by its small, non-enveloped virions containing linear single-stranded DNA genome approximately 5 kb. Parvoviruses entirely reliant on host cell's division machinery for replication. In this study, we demonstrate that CPV-2 infection triggers translation shutoff, process in which nonstructural protein 1 (NS1) plays pivotal role. Our findings indicate NS1-induced shutoff not associated with transcription,...
Respiratory tract and intestinal diseases are common threats to feline health. Coinfection with multiple pathogens is not rare among clinical infectious cases. Rapid diagnosis of these coinfections great significance for timely effective treatment. In this study, two novel multiplex polymerase chain reactions (mPCRs) were established simultaneous detection four associated the (feline coronavirus (FCoV), astrovirus (FeAstV), panleukopenia virus (FPV) kobuvirus (FeKoV)) five respiratory...
Feline parvovirus often causes a fatal infectious disease and has serious impact on domestic cats wild felines. chaphamaparvovirus (FeChPV) is novel type of feline that been successively identified in Canada, Italy, Turkey. The prevalence pathogenicity FeChPV other regions still unknown. In this study, we recorded the detection cat shelter China. A high (81.08%, 30/37) was detected with symptoms upper respiratory tract (URTD) shelter. Multiple pathogen testing indicated coinfection rates 80%...