Alejandro Ramírez‐Hernández

ORCID: 0000-0001-8689-5930
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Research Areas
  • Vector-borne infectious diseases
  • Viral Infections and Vectors
  • Mosquito-borne diseases and control
  • Yersinia bacterium, plague, ectoparasites research
  • Vector-Borne Animal Diseases
  • Insect symbiosis and bacterial influences
  • Leptospirosis research and findings
  • Insect and Pesticide Research
  • Study of Mite Species
  • Forensic Entomology and Diptera Studies
  • Helminth infection and control
  • Bird parasitology and diseases
  • Bat Biology and Ecology Studies
  • Bee Products Chemical Analysis
  • Atrial Fibrillation Management and Outcomes
  • Venous Thromboembolism Diagnosis and Management
  • Insects and Parasite Interactions
  • Amphibian and Reptile Biology
  • Research on Leishmaniasis Studies
  • Insect Utilization and Effects
  • Animal testing and alternatives
  • Acute Myocardial Infarction Research
  • Species Distribution and Climate Change
  • Plant Virus Research Studies
  • Parasite Biology and Host Interactions

Universidad Nacional de Colombia
2015-2024

University of La Salle
2022-2024

Instituto Nacional de Cardiología
2023

The University of Texas Medical Branch at Galveston
2013-2023

Fundación Universitaria de Ciencias de la Salud
2022

Pontificia Universidad Javeriana
2015-2022

Universidad Libre de Colombia
2022

Universidade de São Paulo
2015-2021

Universidade Cidade de São Paulo
2017-2019

The University of Texas Southwestern Medical Center
2015

Background Brazilian spotted fever (BSF), caused by the bacterium Rickettsia rickettsii, has been associated with transmission tick Amblyomma sculptum, and one of its main hosts, capybara (Hydrochoerus hydrochaeris). Methods During 2015–2019, we captured capybaras ticks in seven highly anthropic areas São Paulo state (three endemic four nonendemic for BSF) two natural Pantanal biome, all established populations capybaras. Results The BSF-endemic were characterized much higher burdens on both...

10.1371/journal.pntd.0007734 article EN cc-by PLoS neglected tropical diseases 2019-09-06

The aim of this work was to detect and identify Rickettsia species in ticks collected rural areas Villeta, Colombia. Tick specimens were from domestic animals walls houses five villages Villeta town humans Naranjal village (same town). Moreover, a flea the same area also processed. DNA extracted tested by conventional, semi-nested, nested PCR reactions targeting rickettsial genes. In village, nymph Amblyomma cajennense sensu lato amplified using primers for ompA sequenced (100% identity with...

10.1089/vbz.2015.1841 article EN Vector-Borne and Zoonotic Diseases 2016-01-20

Rickettsioses caused by Rickettsia felis are an emergent global threat. Historically, the northern region of province Caldas in Colombia has reported murine typhus cases, and recently, serological studies confirmed high seroprevalence for both R. typhi. In present study, fleas from seven municipalities were collected dogs, cats, mice. DNA was extracted amplified polymerase chain reaction (PCR) to identify gltA, ompB, 17kD genes. Positive samples sequenced species Rickettsia. Of 1,341 fleas,...

10.4269/ajtmh.12-0698 article EN American Journal of Tropical Medicine and Hygiene 2013-07-23

Etiology of acute undifferentiated febrile syndrome (AUFS) is often unknown, leading to inaccurate diagnosis and treatment. Villeta town has been identified as an endemic area for spotted fever group (SFG) rickettsioses but little known about possible amplifier hosts other Rickettsia species different from rickettsii. Besides, few studies have approached AUFS etiologies in the region. We investigated role dengue, leptospirosis, rickettsioses, human anaplasmosis, Q causes patients Villeta....

10.4269/ajtmh.16-0442 article EN American Journal of Tropical Medicine and Hygiene 2017-09-07

We evaluated extracts taken from S. magellanica third instar larvae fat body and haemolymph using a diabetic rabbit model compared this to the effect obtained with same substances Lucilia sericata larvae. Alloxan (a toxic glucose analogue) was used induce experimental diabetes in twelve rabbits. Dorsal wounds were made each animal they infected Staphylococcus aureus Pseudomonas aeruginosa. They then treated lyophilized selected blowflies' bodies. Each wound by rating scales histological...

10.1155/2015/270253 article EN cc-by Journal of Diabetes Research 2015-01-01

Abstract Brazilian spotted fever (BSF), caused by Rickettsia rickettsii , is the most lethal tick-borne disease in western hemisphere. In Brazil, Amblyomma sculptum ticks are main vector. Capybaras ( Hydrochoerus hydrochaeris ), largest living rodents of world (adults weighing up to 100 Kg), have been recognized as amplifying hosts R. for A. BSF-endemic areas; i.e., once primarily infected, capybaras develop bacteremia a few days, when feeding acquire rickettsial infection. We conducted...

10.1038/s41598-020-57607-5 article EN cc-by Scientific Reports 2020-01-22

Amblyomma sculptum is an important vector of Rickettsia rickettsii, causative agent Rocky Mountain spotted fever and the most lethal tick-borne pathogen affecting humans. To feed on vertebrate host's blood, A. secretes a salivary mixture, which may interact with skin resident dendritic cells (DCs) modulate their function. The present work was aimed at depicting saliva-host DC network biochemical nature immunomodulatory component(s) involved in this interface. saliva inhibits production...

10.3389/fimmu.2019.00118 article EN cc-by Frontiers in Immunology 2019-02-04

Rickettsiae are obligate intracellular Gram-negative bacteria that the causative agent of rickettsioses and spread to vertebrate hosts by arthropods. There no previous reports isolation Rickettsia amblyommatis for Colombia.A convenience sampling was executed in three departments Colombia direct collection adult ticks on domestic animals or over vegetation. Ticks were screened presence spp. real-time polymerase chain reaction (qPCR) amplifying citrate synthase gene (gltA), positive sample...

10.1186/s13071-023-05950-7 article EN cc-by Parasites & Vectors 2023-09-20

Abstract Ticks of the Amblyomma maculatum (Ixodida Ixodidae) complex, cajennense complex and ovale are known to transmit various Rickettsia species in Colombia, but their exact distribution is unknown. We built several models based on current climate projected future changes using a maximum entropy approach. A total 314 records A. (65.9%; n = 207), (22.9%; 72), (11.1%; 35) were obtained. has Pacific, Caribbean Andean regions could be potentially found Amazon. Orinoco regions. mixtum can near...

10.1093/jme/tjae100 article EN Journal of Medical Entomology 2024-09-09

ABSTRACT. Murine typhus is an acute undifferentiated febrile illness caused by Rickettsia typhi . In the United States, its reemergence appears to be driven a shift from classic rat–rat flea cycle of transmission one involving opossums ( Didelphis virginiana ) and cat fleas. Little known ability act as reservoir amplifying host for R. Here, we use Monodelphis domestica (the laboratory opossum) surrogate D. Opossums were inoculated via intraperitoneal (IP) or intradermal (ID) route with 1 ×...

10.4269/ajtmh.21-1076 article EN American Journal of Tropical Medicine and Hygiene 2022-06-13

Ticks of genus Ornithodoros are nidicolous parasites associated with a wide array vertebrates. In humans, their bites cause hypersensitivity reactions and capable to transmit pathogens health concern. the department Córdoba, Caribbean region Colombia, first report an soft tick was made in 1980 by Betancourt, who described collection talaje human dwellings. Nevertheless, current records O. South America have been questioned likely correspond misidentifications morphologically similar species....

10.3389/fvets.2021.704399 article EN cc-by Frontiers in Veterinary Science 2021-06-23
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