A5114375721- Malaria Research and Control
- vaccines and immunoinformatics approaches
- Mosquito-borne diseases and control
- Tuberculosis Research and Epidemiology
- Vector-borne infectious diseases
- Cervical Cancer and HPV Research
- Clostridium difficile and Clostridium perfringens research
- Mycobacterium research and diagnosis
- RNA and protein synthesis mechanisms
- HIV Research and Treatment
- Invertebrate Immune Response Mechanisms
- Complement system in diseases
- Gut microbiota and health
- Monoclonal and Polyclonal Antibodies Research
- Trypanosoma species research and implications
- Immunotherapy and Immune Responses
- Hepatitis B Virus Studies
- T-cell and B-cell Immunology
- Antimicrobial Peptides and Activities
- Genital Health and Disease
- Reproductive tract infections research
- Computational Drug Discovery Methods
- Forensic Entomology and Diptera Studies
- Parasites and Host Interactions
- Immune Cell Function and Interaction
Universidad Nacional de Colombia
2007-2025
Fundación Instituto de Inmunología de Colombia
2016-2025
University of Applied and Environmental Sciences
2022-2025
Universidad Santo Tomás
2021-2023
Universidad del Rosario
2011-2020
Weatherford College
2015
Asociación Colombiana de Infectología
2015
Universidad Colegio Mayor de Cundinamarca
2012
Instituto de Hematología e Inmunología
2003
Is it possible to identify new mutations potentially associated with non-syndromic primary ovarian insufficiency (POI) via whole-exome sequencing (WES)? WES is an efficient tool study genetic causes of POI as we have identified mutations, some which lead protein destablization contributing the disease etiology. a frequently occurring complex pathology leading infertility. Mutations in only few candidate genes, mainly by Sanger sequencing, been definitively related pathogenesis disease. This...
Recurrent pregnancy loss is a frequently occurring human infertility-related disease affecting ~1% of women. It has been estimated that the cause remains unexplained in >50% cases which strongly suggests genetic factors may contribute towards phenotype. Concerning its molecular aetiology numerous studies have had limited success identifying disease's causes. This might due to fact hundreds genes are involved each physiological step necessary for guaranteeing reproductive mammals. In such...
SUMMARY Bovine leukaemia virus (BLV) is the causative agent of enzootic bovine leucosis, which has been reported worldwide. BLV found recently in human tissue and it could have a significant impact on health. A possible hypothesis regarding viral entry to humans through consumption infected foodstuffs. This study was aimed at detecting presence DNA raw beef fresh milk for consumption. Nested PCR directed gag gene (272 bp) used as diagnostic test. products were confirmed by Sanger sequencing....
Larval therapy (LT) is an alternative treatment for healing chronic wounds; its action based on debridement, the removal of bacteria and stimulating granulation tissue. The most important mechanism when using LT combating infection depends larval excretions secretions (ES). Larvae are protected against by a spectrum antimicrobial peptides (AMPs); special interest in AMPs has also risen regarding understanding their role wound since they degrade necrotic tissue kill different during LT....
Antibiotic resistance is at dangerous levels and increasing worldwide. The search for new antimicrobial drugs to counteract this problem a priority health institutions organizations, both globally in individual countries. Sarconesiopsis magellanica blowfly larval excretions secretions (ES) are an important source isolating peptides (AMPs). This study aims identify characterize S. AMP. RP-HPLC was used fractionate ES, using C18 columns, their activity evaluated. peptide sequence of the...
Background Infection with multiple types of human papillomavirus (HPV) is one the main risk factors associated development cervical lesions. In this study, samples collected from 1,810 women diverse sociocultural backgrounds, who attended to their screening program in different geographical regions Colombia, were examined for presence lesions and HPV by Papanicolau testing DNA PCR detection, respectively. Principal Findings The negative binomial distribution model used study showed...
Analysing human papillomavirus (HPV) viral load is important in determining the risk of developing cervical cancer (CC); most knowledge to date regarding HPV and lesions has been related HPV-16. This study evaluated association between six prevalent high-risk types Colombia intraepithelial neoplasia (CIN) frequency. 114 women without CIN 59 having confirmed by colposcopy, all them positive conventional PCR for infection initial screening, were included study. Samples tested determine copy...
The mycobacterial cell envelope has been implicated in the pathogenicity of tuberculosis and therefore a prime target for identification characterization surface proteins with potential application drug vaccine development. In this study, genome Mycobacterium H37Rv was screened using Machine Learning tools that included feature-based predictors, general localizers transmembrane topology predictors to identify are potentially secreted M. tuberculosis, or extracellular milieu through different...