A5043366415- Antimicrobial Peptides and Activities
- Forensic Entomology and Diptera Studies
- Insect and Pesticide Research
- Insect Utilization and Effects
- Protein Hydrolysis and Bioactive Peptides
- Insect Pest Control Strategies
- Probiotics and Fermented Foods
- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Animal testing and alternatives
- Bee Products Chemical Analysis
- Beetle Biology and Toxicology Studies
- Venomous Animal Envenomation and Studies
Universidad Nacional Abierta y a Distancia
2021-2022
Instituto Butantan
2018-2022
Universidad del Rosario
2014-2019
Universidade de São Paulo
2018-2019
Larval therapy (LT) is an alternative treatment for healing chronic wounds; its action based on debridement, the removal of bacteria and stimulating granulation tissue. The most important mechanism when using LT combating infection depends larval excretions secretions (ES). Larvae are protected against by a spectrum antimicrobial peptides (AMPs); special interest in AMPs has also risen regarding understanding their role wound since they degrade necrotic tissue kill different during LT....
Antibiotic resistance is at dangerous levels and increasing worldwide. The search for new antimicrobial drugs to counteract this problem a priority health institutions organizations, both globally in individual countries. Sarconesiopsis magellanica blowfly larval excretions secretions (ES) are an important source isolating peptides (AMPs). This study aims identify characterize S. AMP. RP-HPLC was used fractionate ES, using C18 columns, their activity evaluated. peptide sequence of the...
We evaluated extracts taken from S. magellanica third instar larvae fat body and haemolymph using a diabetic rabbit model compared this to the effect obtained with same substances Lucilia sericata larvae. Alloxan (a toxic glucose analogue) was used induce experimental diabetes in twelve rabbits. Dorsal wounds were made each animal they infected Staphylococcus aureus Pseudomonas aeruginosa. They then treated lyophilized selected blowflies' bodies. Each wound by rating scales histological...
Evaluar, en condiciones in vitro, la actividad antibacterial de los extractos cuerpos grasos y hemolinfa larvas tercer estadio Sarconesiopsis magellanica, cual se comparó con efectos obtenidos las mismas sustancias derivadas Lucilia sericata. S. magellanica (Diptera: Calliphoridae) es una mosca importancia principalmente forense, utilizada determinación del intervalo post mortem. Por sus hábitos necrófagos, considerada un modelo potencialmente útil terapia larval. Se extrajeron mediante...
Snake venom contains a variety of toxins with range biological activity, among these cysteine-rich secreted proteins (CRISPs) can be found. The this family have masses 20–30 kDa and display homologous amino acid sequences containing 16 cysteine residues, forming eight disulfide bonds. Some been explored, characterized, described in terms their activity; however, little is known about activities. A search for new antimicrobial molecules ongoing, as the number microbial strains resistant to...
The inappropriate use of antibiotics has led to the accelerated growth resistance antibiotics. search for new therapeutic strategies (i.e., antimicrobial peptides-AMPs) thus become a pressing need.Characterising and evaluating Sarconesiopsis magellanica larval fat body-derived AMPs.Fat body extracts were analysed by reversed-phase high-performance liquid chromatography (RP-HPLC); mass spectrometry was used characterising primary structure AMPs so found. ProtParam (Expasy) analysing AMPs'...
ABSTRACT Lactobacillus acidophilus are Gram-positive bacteria distributed in diverse environments, and as being a component of the normal microbiota gastrointestinal urogenital tract, relevant to humans. Classified lactic acid bacteria, due pro-duction acid, can also produce antimicrobial peptides (AMPs), which is compound synthesized by all forms life aiming for protecting themselves from threats increase their competitivity survive specific environment. AMPs molecules capable inhibiting...
Leishmaniasis is a neglected tropical disease that affects millions of people around the world. Larval excretion/secretion (ES) larvae flies Calliphoridae family has microbicidal activity against Gram-positive and Gram-negative bacteria, in addition to some species Leishmania. Our study aimed at assessing vitro efficacy Lucilia cuprina larval ES promastigote amastigote forms Leishmania amazonensis, elucidating possible mechanisms routes death involved. was able inhibit viability L....