A5058228728- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Synthesis and biological activity
- Cancer Research and Treatments
- Paraoxonase enzyme and polymorphisms
- Circadian rhythm and melatonin
- Essential Oils and Antimicrobial Activity
- Genomics, phytochemicals, and oxidative stress
- Insect Pest Control Strategies
- Seed and Plant Biochemistry
- Cancer Cells and Metastasis
- Biological Activity of Diterpenoids and Biflavonoids
- Autophagy in Disease and Therapy
- Chemical synthesis and pharmacological studies
- Toxoplasma gondii Research Studies
- Redox biology and oxidative stress
- Traditional and Medicinal Uses of Annonaceae
- Immunotoxicology and immune responses
- Pharmaceutical and Antibiotic Environmental Impacts
- Microbial Natural Products and Biosynthesis
- Heavy Metals in Plants
- Medicinal Plants and Neuroprotection
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Rabies epidemiology and control
- Long-Term Effects of COVID-19
Universidade Estadual de Londrina
2017-2024
Cutaneous leishmaniasis is a zoonotic infectious disease broadly distributed worldwide, causing range of diseases with clinical outcomes ranging from self-healing infections to chronic disfiguring disease. The effective immune response this infection yet be more comprehensively understood and fundamental for developing drugs vaccines. Thus, we used experimental models susceptibility (BALB/c) partial resistance (C57BL/6) Leishmania amazonensis investigate the local profile mediators involved...
Abstract CMV reactivation has been widely associated with bacterial sepsis and occurs in approximately 30% of these individuals, is a longer ICU stay, prolongation the need for mechanical ventilation, over 80% increase mortality rate, being directly severe organ dysfunction hemodynamic imbalance. Thus, aim this study was to evaluate role progression. The overall occurrence cytomegalovirus cohort 17.58%. Was observed an plasma levels NO, reduction percentage free days ventilation arterial pH,...
Fluopsin C is an antibiotic compound derived from secondary metabolism of different microorganisms, which possesses antitumor, antibacterial, and antifungal activity. Related to fluopsin antiproliferative activity, the aim this study was examine following parameters: cytotoxicity, genotoxicity, cell cycle arrest, death induction (apoptosis), mitochondrial membrane potential (MMP), colony formation, mRNA expression genes involved in adaptive stress responses cellular utilizing a monolayer. In...
Abstract Studies show that propolis has antimicrobial, antifungal, antiviral, anti-inflammatory, antioxidant, antitumor, and immunomodulatory properties, may protect against diseases such as diabetes, cardiovascular disease, cancer. We aimed to extract compounds of brown with hydroalcoholic solvents evaluate their cytotoxic activity on tumor non-tumor cells by MTT test. tested the solute:solvent ratio (ethanol:water) extraction time in a Shaker incubator (710 rpm) before conducting central...