A5037220381- Research on Leishmaniasis Studies
- Insect Pest Control Strategies
- Fungal Infections and Studies
- Healthcare Regulation
- Antifungal resistance and susceptibility
- Trypanosoma species research and implications
- Toxoplasma gondii Research Studies
- Parasites and Host Interactions
- Insect and Pesticide Research
- Nail Diseases and Treatments
- Essential Oils and Antimicrobial Activity
- Hibiscus Plant Research Studies
- Toxin Mechanisms and Immunotoxins
- RNA Interference and Gene Delivery
- T-cell and Retrovirus Studies
- Healthcare during COVID-19 Pandemic
- Youth, Drugs, and Violence
- Rabies epidemiology and control
- Allelopathy and phytotoxic interactions
- Garlic and Onion Studies
- Phytochemistry Medicinal Plant Applications
- Steroid Chemistry and Biochemistry
- Phytochemistry and biological activities of Ficus species
- Synthesis and Biological Evaluation
- COVID-19 Clinical Research Studies
Universidade Estadual de Londrina
2013-2024
University Alto Vale do Rio do Peixe
2021-2024
Framingham Heart Study
2023
Liga Contra el Cancer
2023
Sociedade Brasileira de Cardiologia
2023
American cutaneous leishmaniasis is a zoonotic disease caused by protozoans of the genus Leishmania. The treatment unsatisfactory, thus, much research effort has been focused on investigating new compounds with lower collateral effects to patients and derived from low-cost sources, such as natural products. In present study, we evaluated in vitro directly effect flavonoid quercetin against Leishmania (Viannia) braziliensis. Quercetin inhibited proliferation promastigote forms at all tested...
Caryocar coriaceum fruits, found in Brazilian Cerrado and Caatinga, are commonly used as food folk medicine, anti‐inflammatory, bactericide, fungicide, leishmanicide, nematicide. Due to the biological potential of this plant, study focuses on evaluation antifungal antileishmanial activities, including anticholinesterase antioxidant tests, correlating with total phenols flavonoids content. Peel extracts contain higher yield analyzed by spectrophotometric methods. HPLC analysis revealed that...
The Leishmaniasis treatment currently available involves some difficulties, such as high toxicity, variable efficacy, cost, therefore, it is crucial to search for new therapeutic alternatives. Over the past few years, research on drugs has focused use of natural compounds chalcones and nanotechnology. In this context, aimed at assessing in vitro leishmanicidal activity free 4-nitrochalcone (4NC) promastigotes encapsulated 4NC L. amazonensis-infected macrophages, well their action mechanisms....
Introduction. Paracoccidioidomycosis (PCM) is a systemic mycosis caused by Paracoccidioides spp. As the disease known to affect mostly men over 40 years old who previously worked handling soil, some cities of agricultural economy in endemic regions may have more cases paracoccidioidal infection. Gap statement. The true frequency PCM cannot be established Brazil because it not mandatory reporting. detection infection assist planning health services, order provide early and prevent its...
Summary Since the new species Paracoccidioides lutzii emerged in 2009, much has been researched on strains previously considered atypical. Still, there is no consensus about recognition of antigens from P. by antibodies directed to other species, which can have great impact Paracoccidioidomycosis ( PCM ) diagnosis. Current research investigated soluble protein/carbohydrate epitopes LDR 2, restrepiensis B339 and americana 3 recognised IgG brasiliensis . Cell free CFA were analysed by:...
The use of compounds from natural or synthetic sources and nanotechnology may represent an alternative to develop new drugs for the leishmaniasis treatment. DETC is inhibitor SOD1 enzyme, which leads increased ROS production, important elimination Leishmania. Thus, our objective was assess leishmanicidal in vitro effect free Diethydithiocarbamate (DETC) loaded beeswax-copaiba oil nanoparticles (DETC-Beeswax-CO Nps) on L. amazonensis forms elucidate possible mechanisms involved parasite...