A5078324647- Heart Failure Treatment and Management
- Health Systems, Economic Evaluations, Quality of Life
- Medication Adherence and Compliance
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Potassium and Related Disorders
- Gout, Hyperuricemia, Uric Acid
- Chronic Disease Management Strategies
- Hearing, Cochlea, Tinnitus, Genetics
- Cardiovascular Function and Risk Factors
- Hearing Loss and Rehabilitation
- Genetic and Kidney Cyst Diseases
- Pharmaceutical studies and practices
- Pain Management and Opioid Use
- Case Reports on Hematomas
- Diabetes Treatment and Management
- Poisoning and overdose treatments
- Gastroesophageal reflux and treatments
- Psoriasis: Treatment and Pathogenesis
- Renal Diseases and Glomerulopathies
- Pharmaceutical Economics and Policy
- Noise Effects and Management
- Medical Malpractice and Liability Issues
- Pharmaceutical industry and healthcare
- Economic and Financial Impacts of Cancer
- Renal and related cancers
University of Zurich
2023
University of New Haven
2020
Optum (United States)
2014-2019
Novartis (United States)
2016
Nearly 38 million individuals in the United States have untreated hearing loss, which is associated with cognitive and functional decline. National initiatives to address loss are currently under way.To determine whether increased health care cost utilization on basis of data from a claims database.Retrospective, propensity-matched cohort study persons without based for services rendered between January 1, 1999, December 31, 2016, large insurance database. There were 154 414, 44 852, 4728...
Because hearing loss is highly prevalent and treatable, determining its association with morbidity has major public health implications for disease prevention the maintenance of in adults loss.To investigate between diagnosis incident medical comorbidities 50 years or older.Retrospective, propensity-matched cohort study using administrative claims data from commercially insured Medicare Advantage members a geographically diverse US plan. Adults older services rendered January 1, 2000, to...
A 2016 Centers for Disease Control and Prevention prescribing guideline cautioned against higher-dose long-term opioid therapy recommended tapering daily doses by approximately 10% per week if the risks outweigh benefits. Warnings have since appeared regarding potential hazards of rapid tapering.
Background: Home clinical care (HCC) includes home-based medical (HBMC—medical visits in the home) and skilled home health (skilled nursing or therapy visits). Over 7 million older adults would benefit from HCC; however, we know surprisingly little about homebound HCC. Objective: To describe HCC received by using claims data within OptumLabs Data Warehouse. Research Design: Using administrative for commercial Medicare Advantage enrollees, morbidity profiles, service use, coordination...
Objectives For most gout patients, excruciatingly painful attacks are the major clinical burden of disease. The goal this study was to assess association frequent flares with healthcare burden, and quantify how much lower gout-related costs resource use for those infrequent compared flares. Design Retrospective cohort study. Setting Administrative claims data from a large US health plan. Participants Patients aged 18 years or above, evidence based on medical pharmacy between January 2009...
Objective While frequent contact with diabetes care providers may improve glycemic control among patients type 1 (T1D), in-person visits are labor-intensive and costly. This study was conducted to assess the impact of an intensive remote therapy (IRT) intervention for pediatric T1D. Methods Pediatric T1D were randomized IRT or conventional (CC) 6 months. Both cohorts continued routine quarterly clinic uploaded device data; cohort, data reviewed contacted if regimen adjustments indicated....
Heart failure (HF) is a severe chronic disease with growing prevalence and health care burden as well high mortality. End-of-life cost data for patients HF may inform medication therapy management.To (a) characterize real-world sample of who died; (b) estimate costs 6 months semiannually 24 months, before death; (c) examine associations between patient characteristics predeath costs.This was retrospective study commercial Medicare Advantage Part D (MAPD) enrollees (aged ≥ 18 years), using...
The objective of this study was to assess the real-world comparative effectiveness continuing on allopurinol versus switching febuxostat.In a retrospective claims data enrollees in health plans affiliated with Optum, we evaluated patients from February 1, 2009, May 31, 2012, gout diagnosis, pharmacy claim for or febuxostat, and at least 1 serum uric acid (SUA) result available during follow-up period. Univariate multivariable-adjusted analyses (controlling patient demographics clinical...
To examine the association of patient/clinical characteristics with mortality and readmission following a heart failure (HF)-related hospitalization.Claims data, linked to laboratory, race/ethnicity, from large US health plan were utilized identify individuals ≥1 inpatient claim diagnosis code for HF (1 January 2008-30 September 2012). Study variables analyzed using descriptive multivariable approaches associated post-discharge outcomes.Primary outcomes included readmission.A total 126,214...
Background: Autosomal dominant polycystic kidney disease (ADPKD), a hereditary nephropathy, eventually leads to end-stage renal (ESRD), typically by mid-life. Objectives: The objective of this study was assess real-world healthcare resource utilization and cost among commercially insured (COM) Medicare Advantage (MAPD) ADPKD patients in addition the profile chronic (CKD) stage. Methods: Patients diagnosed with (two or more claims) ≥30 days continuous medical pharmacy benefits no evidence...
To examine characteristics, healthcare utilization and costs among patients with psoriasis who have high medical costs.This is a retrospective study of continuous enrollment from 1 January 2011 to 31 December 2013 in large US health plan. Total paid 2012 excluding biologics (to identify costliest not due biologic costs) were used create cohorts representing the top 10% (T10) bottom 90% (B90) expenditures. Demographics, comorbidities, prescriptions, all-cause psoriasis-related compared...
Due to the heterogeneity of older people, it is difficult identify reliable factors influencing oral health.
Homebound patients who could benefit from high-quality, cost-saving longitudinal home-based medical care cannot be identified easily by hospitals, health systems, or payers. Further, without a well-defined population denominator, assessments of quality are inadequate. We addressed these gaps using the OptumLabsTM Data Warehouse, which includes more than 3 million commercial and Medicare 2014 enrollees age 65 older. two patient phenotypes may care: (1) with complex comorbid conditions already...