A5061659781- Ultrasound and Hyperthermia Applications
- Radiation Therapy and Dosimetry
- Chronic Myeloid Leukemia Treatments
- Hemodynamic Monitoring and Therapy
- Chronic Lymphocytic Leukemia Research
- PI3K/AKT/mTOR signaling in cancer
- Epilepsy research and treatment
- Advanced Radiotherapy Techniques
- Radioactive element chemistry and processing
- Glutathione Transferases and Polymorphisms
- Chemical Synthesis and Characterization
- Analytical Methods in Pharmaceuticals
- Photoacoustic and Ultrasonic Imaging
- Ureteral procedures and complications
- Anesthesia and Sedative Agents
- Treatment of Major Depression
- Neuroscience and Neuropharmacology Research
- Mitochondrial Function and Pathology
- Monoclonal and Polyclonal Antibodies Research
- Boron Compounds in Chemistry
- Genomics, phytochemicals, and oxidative stress
- Radiation Detection and Scintillator Technologies
- Ocular and Laser Science Research
- Effects of Radiation Exposure
- Anesthesia and Pain Management
Beijing Chao-Yang Hospital
2017-2024
Capital Medical University
2017-2024
National Institute for Radiological Protection
2017-2024
Anhui Medical University
2023-2024
Dezhou University
2019
Abstract Background and objective Definity is an ultrasound contrast agent consisting of phospholipids-encapsulated perfluoropropane (PFP), also known as perflutren, microspheres, which initially designed to enhance echocardiographic images. With no pharmacologic action, can increase the backscatter resulting enhanced signals. The this study was determine pharmacokinetics (PKs), Pharmacodynamics (PDs) safety in healthy male female Chinese volunteers. Methods A simple GC-MS method developed...
Sonazoid is an ultrasound contrast agent based on microbubbles (MB) containing perfluorobutane (PFB) gas. approved in Japan, Korea and Norway for contrast-enhanced ultrasonography of focal liver lesions breast (Japan only). The objective this study was to determine the pharmacokinetics (PKs) safety Chinese healthy volunteers (HVs) evaluate potential ethnic differences PKs between Caucasian HVs. administered as intra-venous bolus injection at clinical dose 0.12 μL or 0.60 MB/kg body weight...
Olanzapine, a second-generation atypical antipsychotic drug, is widely used for schizophrenia and moderate to severe mania associated with bipolar disorders. This open-label, randomized, single-dose, 2-sequence, 2-period crossover, comparative pharmacokinetic study assessed the bioequivalence of 5 mg olanzapine administered in tablet (R) or disintegrating (T) formulation healthy Chinese volunteers under both fasting fed conditions. Numbers enrolled subjects were 30 24 treatments,...
Abstract Background and Objective: Definity is an ultrasound contrast agent consisting of phospholipids-encapsulated perfluoropropane (PFP), also known as perflutren, microspheres, which initially designed to enhance echocardiographic images. With no pharmacologic action, can increase the backscatter resulting enhanced signals. The objective this study was determine pharmacokinetics (PKs), Pharmacodynamics (PDs) safety in healthy male female Chinese volunteers. Methods : A simple GC-MS...
The decreased occupational dose limit for eye lens has lead to an extensive focus on the monitoring and protection staff in interventional procedures. Based literature investigation of existing measurement calculation results, efficiency influence factors protective equipments are analyzed, suggestions selection use them provided. main contribution is unshielded radiation which reaches eyes directly. key inflence equipment geometric conditions such as structure, beam projection, position...
Objective To investigate the clinical effects of two different surgical methods for treatment horseshoe-shaped anal fistula. Methods A retrospective study was performed on 98 cases patients with fistula who were admitted from January 2016 to June 2018.According types surgery, divided into A group and B group, 49 in each group.There 26 male 23 female aged (45.23±2.67) years old, ranged 24 68.There 27 22 (46.19±2.34) 66.In A, posterior midline anus cut open.A radial incision made at...
Clevidipine is an ultrashort-acting dihydropyridine calcium antagonist, which can control blood pressure accurately. It necessary to develop a liquid chromatography–tandem mass spectrometry (LC-MS/MS) method quantitate clevidipine and its active metabolite H152/81 for clinical pharmacokinetic study therapeutic drug monitoring. Liquid–liquid extraction was used sample preparation, clevidipine-d 7 H152/81- 13 C-d 3 were chosen as the isotope internal standard. The chromatographic separation...
Aims: A randomized, open-label, two-period, two-sequence crossover study was carried out for evaluating the bioequivalence of test (T) and reference (R) formulation gefitinib in healthy Chinese volunteers. Methods: total eighty subjects were enrolled randomized into two sequence groups. All orally administered T or R at dose 250 mg. The plasma samples obtained before after administration until post-dose 168 hour, drug concentrations analyzed using validated high-performance liquid...