A5101635848- Pediatric Hepatobiliary Diseases and Treatments
- Congenital Anomalies and Fetal Surgery
- Cerebrospinal fluid and hydrocephalus
- Epilepsy research and treatment
- Glioma Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Fetal and Pediatric Neurological Disorders
- Neonatal and fetal brain pathology
- Tracheal and airway disorders
- Moyamoya disease diagnosis and treatment
- Congenital Diaphragmatic Hernia Studies
- Polyomavirus and related diseases
- Intracranial Aneurysms: Treatment and Complications
- Pharmacological Effects and Toxicity Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Neuroscience and Neuropharmacology Research
- Vestibular and auditory disorders
- Meningioma and schwannoma management
- Occupational and environmental lung diseases
- Tuberous Sclerosis Complex Research
- Connective Tissue Growth Factor Research
- Parkinson's Disease Mechanisms and Treatments
- Vascular Malformations Diagnosis and Treatment
- Circular RNAs in diseases
- Ocular Oncology and Treatments
Chongqing Medical University
2024
Shanghai Children's Hospital
2024
Children's Hospital of Fudan University
2011-2023
First Affiliated Hospital of Xi'an Jiaotong University
2022
Wuxi People's Hospital
2022
Beijing Chao-Yang Hospital
2019
Capital Medical University
2019
The Sixth People's Hospital of Shenyang
2013
Wuxi Taihu Hospital
2011
Fudan University
2011
Objective To evaluate the association between single-nucleotide polymorphisms (SNPs) in RNA-seq identified mRNAs and silicosis susceptibility. Methods A comprehensive was performed to screen for differently expressed peripheral blood lymphocytes of eight subjects exposed silica dust (four cases four healthy controls). Following this, SNPs located on shortlisted mRNAs, which may affect susceptibility, were screened through silicosis-related genome-wide studies (GWAS) (155 141 controls),...
BACKGROUND AND OBJECTIVES: Aimed to investigate the safety, accuracy, and efficacy of stereo electroencephalography (SEEG) in children various ages, with particular emphasis on those younger than 3 years. There is limited guidance regarding whether SEEG can conducted very young children. METHODS: This retrospective study was between July 2018 August 2022. It involved 88 patients who underwent 99 robot-assisted procedures at our center. The were categorized into groups based their age time...
Biliary atresia (BA) is a devastating liver disease in infants. Progressive hepatic fibrosis often observed postoperative patients with BA even after successful Kasai portoenterostomy procedure. MicroRNA-222 (miRNA) has been linked to the activation of stellate cells and progression fibrosis.In this study, miR-222 expression profile infants anicteric choledochal cyst (CC) was determined. The functional effect inhibition on growth human cell line LX-2 also evaluated. downstream signaling...
Ventriculoperitoneal (VP) shunt complications are common, but abdominal rare. The objective of this report is to present 2 cases intestinal obstruction due a VP and review the literature for data on rare occurrence. A 4-month-old boy received surgical resection medulloblastoma was inserted manage progressive hydrocephalus. Two months later, he admitted with intermittent vomiting, plain radiography showed complete obstruction. Emergency laparotomy revealed an adhesive around catheter,...
Abstract Background Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous syndrome involved in many organ systems. At the same time, epilepsy most common manifestation and more than 50% of TSC patients present with intractable epilepsy. This study investigated efficacy safety optimized high‐density stereoelectroencephalography (SEEG) guided radiofrequency thermocoagulation (RF‐TC) treating TSC‐related Methods Nine children refractory were treated first‐stage SEEG‐Guided...
Objective: To compare the effects of hepatic portocholecystostomy (HPC) and Kasai procedure for treatment biliary atresia with patent distal extrahepatic bile ducts (BA PDEBD) to determine reasons differences between two procedures. Methods: The case files 29 patients BA PDEBD were reviewed retrospectively. Twenty treated procedure, 9 HPC. We compared rate jaundice clearance, incidence cholangitis, survival rates native liver, clinical outcomes groups. Healthy gallbladders collected...
Abstract Researchers have widely acknowledged the therapeutic value of epilepsy surgery for drug-resistant epilepsy. Nonetheless, there is a substantial gap in surgical treatment appropriate candidates owing to several factors, particularly population young children. To standardize protocols preoperative evaluation and children surgery, China Association Against Epilepsy has appointed an expert task force pediatric patients. It adopted modified Delphi method performed two rounds surveys...
Olanzapine, a second-generation atypical antipsychotic drug, is widely used for schizophrenia and moderate to severe mania associated with bipolar disorders. This open-label, randomized, single-dose, 2-sequence, 2-period crossover, comparative pharmacokinetic study assessed the bioequivalence of 5 mg olanzapine administered in tablet (R) or disintegrating (T) formulation healthy Chinese volunteers under both fasting fed conditions. Numbers enrolled subjects were 30 24 treatments,...
The aim of present study was to evaluate the incidence, clinical symptoms, pathological characteristics, surgical treatment strategies and prognosis brain tumors in children aged two under. current obtained data regarding 32 consecutive infants young years under, who were treated for Children's Hospital Fudan University (Shanghai, China) between 2003 2013. types tumor, manifestations, location, histological features, applied outcomes retrospectively evaluated. male female ratio 1.13:1, among...
Thoracoscopic segmentectomy is a common surgical procedure in thoracic surgery today. However, identifying the intersegmental plane difficult process. Therefore, we evaluated feasibility of arterial ligation method for determining and compared demarcation status with intravenous indocyanine green (ICG).We retrospectively reviewed records 35 patients peripheral small lung nodules who underwent thoracoscopic between May December 2020. First, preoperative three-dimensional reconstruction was...
Background: Giant hypothalamic hamartomas (HHs) are extremely rare lesions, for which the treatment is challenging. While minimally invasive treatments such as radiofrequency thermal coagulation and laser ablation have improved seizure outcomes, multiple operations often required. This study investigated value of one-stage stereo-array thermocoagulation based on stereotactic electroencephalography (SEEG) pediatric giant HHs. Methods: We analyzed clinical data six patients with HHs (masses a...
Objectives To evaluate the therapeutic effect of encephaloduromyosynangiosis (EDMS) in young children for moyamoya disease(MMD). Methods Twenty-seven MMD chilidren confirmed by digital subtraction angiography (DSA) or magnetic resonance (MRA) our center were admitted between January 2011 and September 2013. The clinical manifestation was described as below: 1 with cerebral hemorrhage history, 26 Ischemic history. Eight left brain hemispheres, 6 right hemispheres 13 bilateral operated....