A5043365742- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Nanoparticles: synthesis and applications
- Graphene and Nanomaterials Applications
- Advanced biosensing and bioanalysis techniques
- 2D Materials and Applications
- Prostate Cancer Diagnosis and Treatment
- Aluminum toxicity and tolerance in plants and animals
- Luminescence Properties of Advanced Materials
- Nanoparticle-Based Drug Delivery
- Advanced Radiotherapy Techniques
- Supramolecular Self-Assembly in Materials
- Radiation Therapy and Dosimetry
- Prostate Cancer Treatment and Research
- Energetic Materials and Combustion
- Catalytic Processes in Materials Science
- Photoacoustic and Ultrasonic Imaging
- Nanocluster Synthesis and Applications
- Sulfur Compounds in Biology
- Luminescence and Fluorescent Materials
- Neuroinflammation and Neurodegeneration Mechanisms
- Curcumin's Biomedical Applications
- Heavy Metal Exposure and Toxicity
- Thermal Radiation and Cooling Technologies
- Birth, Development, and Health
University of Chinese Academy of Sciences
2017-2022
Institute of High Energy Physics
2017-2022
Chinese Academy of Sciences
2017-2022
National Center for Nanoscience and Technology
2017-2022
Shanghai Jiao Tong University
2021
University of Washington
2002
As demonstrated by preclinical and clinical studies, it is often difficult to eradicate tumors, particularly those that are deep-located, with photothermal therapy (PTT) alone because of the intrinsic drawbacks optical therapy. To increase therapeutic effect PTT reduce its significant side-effects, a new direction involving combination other techniques highly desirable. Recently, two-dimensional (2D) transition metal dichalcogenides (TMDCs), typical ultrathin 2D layer nanomaterials, have...
Abstract With the rapid development of nanotechnology, emerging transition‐metal dichalcogenides (TMDCs) have become one most promising inorganic nanomaterials for medical applications due to their distinctive structures and properties. TMDCs with different sizes morphologies exhibit unique structural advantages, as well versatile However, concerning practicability biomedical applications, routes toward synthesis chemical/physical functionalization biosystem must be identified. Herein,...
The radioresistance of tumor cells is considered to be an Achilles' heel cancer radiotherapy. Thus, effective and biosafe radiosensitizer highly desired but hitherto remains a big challenge. With the rapid progress nanomedicine, multifunctional inorganic nanoradiosensitizers offer new route overcome enhance efficacy Herein, poly(vinylpyrrolidone) (PVP)-modified Bi2WO6 nanoplates with good biocompatibility were synthesized through simple hydrothermal process applied as for enhancement...
Early diagnosis of acute liver failure (ALF) is critical for curable treatment patients, because most existing ALF therapies have narrow therapeutic time windows after disease onset. Reactive oxygen species (ROS), which lead to the sequential occurrences hepatocyte necrosis and leakage alanine aminotransferase (ALT), represent early biomarkers ALF. Photoacoustic imaging emerging as a powerful tool in vivo ROS. However, high-performance probes that can boost photoacoustic signals short-lived...
Low water solubility, extensive metabolism, and drug resistance are the existing unavoidable disadvantages of insoluble curcumin in biomedical applications. Herein, we employed d-α-tocopherol polyethylene glycol 1000 succinate (TPGS)-functionalized near-infrared (NIR)-triggered photothermal mesoporous nanocarriers with bamboo charcoal nanoparticles (TPGS-BCNPs) to load deliver for improving its bioavailability. This system could considerably increase accumulation cancer cells enhanced...
The past decades have witnessed an increasing interest in the exploration of room temperature gallium-based liquid metal (LM) field microfluidics, soft robotics, electrobiology, and biomedicine. Herein, this study for first time reports utilization nanosized gallium-indium eutectic alloys (EGaIn) as a radiosensitizer enhancing tumor radiotherapy. sodium alginate (Alg) functionalized EGaIn nanoparticles (denoted EGaIn@Alg NPs) are prepared via simple one-step synthesis method. coating Alg not...
Inorganic nanomaterials are pivotal foundational materials driving traditional industries’ transformation and emerging sectors’ evolution. However, their industrial application is hindered by the limitations of conventional synthesis methods, including poor batch stability, scaling challenges, complex quality control requirements. This review systematically examines strategies for constructing automated systems to enhance production efficiency inorganic nanomaterials. Methodologies...
Developing robust and high-efficient synthesis approaches has significant importance for the expanded applications of upconversion nanoparticles (UCNPs). Here, we report a high-throughput strategy to fabricate water-dispersible core-shell structured UCNPs. Firstly, successfully obtain more than 10 grams core UCNPs with high quality from one-pot reaction using liquid rare-earth precursors. Afterwards, different are fabricated by successive layer-by-layer get enhanced fluorescence property....
Silica nanoparticles (SiO2-NPs) are currently among the most widely used nanomaterials, but their potentially adverse effects on brain development remain unknown. The developing is extremely sensitive to NP neurotoxicity during early postnatal period.Herein, we investigated of SiO2-NPs (doses 10, 20, or 50 mg with a particle size ~91 nm, equivalent aerosol mass concentrations 55.56, 111.11, and 277.78 mg/m3, respectively) exposure from day (P) 1 P7 hippocampal precursor proliferation at P8...
Neural stem cells are characterized by self-renewal and multipotency, a capacity to regenerate in response brain injury or neurodegenerative disease.
Objective: To explore the effects of cigarette smoke exposure during pregnancy on quality oocytes and whole genome DNA methylation in offspring female mice period germinal vesicle (GV) . Methods: The pregnant 7 d were divided into 3 groups, 0, 0.5, 1 lit cigarettes cabinet (volume 18 L) , at 9 am pm for h twice daily, until delivery. When 6 weeks old, organ index number follicles ovary detected by weighing making HE stained sections. GV stage obtained Hoechst 33342 staining indirect...
Singlet oxygen (1O2) is extensively employed by reactive species (ROS)-based cancer therapies, such as photodynamic therapy (PDT) and chemodynamic (CDT). However, the dependences of PDT on light CDT complex reactions greatly limit their 1O2-generating efficiencies. Here, we exploit strain electronic effects to fabricate a bimetallic nanocatalyst coating gold nanorod (AuNR) with ~2 platinum (Pt) atomic layers (AuPt0.09), which efficiently generates 1O2 from ground-state (3O2)...
Purpose: (1) To develop an intra‐operative dose evaluation and optimization system for prostate brachytherapy using complementary imaging modalities (fluoroscopy seed localization ultrasound delineation). (2) evaluate the usefulness of dosimetry system. Method Materials: Several algorithms were developed to realize concept fluoroscopy‐ultrasound based dosimetry. These include automated detection, 3D reconstruction, patient motion correction, computer‐assisted contouring, seeds‐prostate...