A persistent left superior vena cava (PLSVC) is the most common thoracic venous anomaly. This anomaly can impact evaluation and treatment of supraventricular tachyarrhythmia (SVA). The aim this study was to assess proportion characteristics PLSVC in adult SVA patients. From July 2002 2012, clinical procedural data from databases 10 cardiac electrophysiology laboratories Yeungnam region Republic Korea were reviewed. Of 6662 patients who underwent an EP or catheter ablation during 10-year...

The purpose of the present study was to determine whether thoracic veins may act as ectopic pacemakers and nodelike cells rich sympathetic innervation are at sites. We used a 1,792-electrode mapping system with 1-mm resolution map atrial arrhythmias in eight normal dogs during vivo right left stellate ganglia (SG) stimulation before after sinus node crushing. SG triggered significant elevations transcardiac norepinephrine levels, tachycardia all dogs, two dogs. Sinus crushing resulted slow...

This study was performed to describe clinical characteristics of patients with left ventriculars (LV) dysfunction and implantable cardioverter-defibrillator (ICD), evaluate the effect ICD therapy on survival in Yeongnam province Korea.From a community-based device registry (9 centers, province, from November 1999 September 2012), 146 LV an implanted for primary or secondary prophylaxis, were analyzed. The divided into two groups, based etiology (73 ischemic cardiomyopathy 73 non-ischemic...

Background/Aims Increased left atrial (LA) size has been proposed as a predictor of poor cardiovascular outcome in the elderly. In present study, we evaluated relationship between LA and stroke subjects all ages who presented with preserved ventricular systolic function (LVSF) sinus rhythm (SR), investigated relationships other echocardiographic parameters diastolic function. Methods A total 472 were enrolled study (161 men, 311 women) divided into group (n=75) control (n=397). conventional...

Recent several studies have shown that the genetic variation of SCN5A is related with atrioventricular conduction block (AVB); no study has yet been published in Koreans. Therefore, to determine AVB-associated Korean patients, we investigated patients AVB and compared normal control subjects. We enrolled 113 80 controls cardiac symptoms. DNA was isolated from peripheral blood, all exons (exon 2-exon 28) except untranslated region exon-intron boundaries gene were amplified by multiplex PCR...

Background and Objectives:The plasma concentration of N-terminal pro-brain natriuretic peptide (NT-pro-BNP) is a strong prognostic indicator for patients with heart failure (HF) across all stages the condition.Several clinical trials have demonstrated convincingly that neurohormonal modulation on renin angiotensin system (RAS) decreases NT-pro-BNP level results in favorable outcomes.But there are still limited comparative data neuro-hormonal modulatory effects two RAS inhibitors: converting...

Background and Objectives: The newly developed 2-dimensional ultrasound speckle tracking imaging (2D-STI) has enabled researchers to assess the changes of left ventricular (LV) rotation torsion. aims present study are establish normal values examine effect advancing age on Subjects Methods: We enrolled 182 healthy persons in this study. After examined standard clinical echocardiographic parameters, we obtained degree LV at basal apical levels short axis view with using a customized software...

Left ventricular (LV) dyssynchrony has been commonly detected among hypertensive patients with normal LV systolic function and no evidence of congestive heart failure. The purpose our study was to assess the changes in (SDS(LV)) after antihypertensive treatment, determine relationship between SDS(LV) other conventional echocardiographic parameters.Forty one ejection fraction were enrolled. By performing a study, measured as time difference shortest longest peak myocardial velocities 12...

Due to recent studies that have shown an association between the genetic variation of SCN5A and sick sinus syndrome (SSS), we sought determine if a similar correlation existed in Korean patients with SSS. We enrolled 30 SSS who showed pause (longer than 3.0 s) Holter monitoring, addition 80 controls. All exons including putative splicing sites gene were amplified by polymerase chain reaction sequenced either directly or following subcloning. Wild-type single nucleotide polymorphisms...

In patients with nonvalvular atrial fibrillation (AF), the risk of stroke is five times that a normal sinus rhythm. Antithrombotic therapy has pivotal role for prevention stroke. With advent new oral anticoagulants (NOAC), strategy antithrombotic undergone significant changes due to its better efficacy, safety, and convenience when compared warfarin or an antiplatelet regimen. Furthermore, aspects in have revealed efficacy regimens weak while major bleeding not significantly different...

Background: Studies on the efficacy of implantable cardioverter-defibrillator (ICD) therapy for primary prevention in Asian patients are relatively lacking compared to those secondary prevention.Also, it is important stratify which will benefit from ICD prevention.Methods: Of 483 consecutive who received new implantation 9 centers Korea, 305 with reduced left ventricular systolic function and/or documented fibrillation/tachycardia were enrolled and divided into (n = 167) groups 138).Results:...

Abstract Objectives Angiotensin system is a major cause of heart failure and arrhythmia. Despite lack direct evidence that oxidative stress causes ventricular arrhythmia, reversal considered plausible therapy. This study evaluated the Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor could suppress arrhythmia in cardiac hypertrophy rabbit model. Methods (Ang II) or saline was administrated for 2 weeks via osmotic minipumps implanted subcutaneously midclavicular region. Hearts...

There have been very few pathophysiologic studies on isolated diastolic dysfunction. We hypothesized that the characteristics of dysfunction would be located, clinical continuum, between those a normal heart and failure.We enrolled 102 subjects who had no history overt symptoms failure left ventricular ejection fraction more than 50%. They were examined for myocardial deformation rotation using two-dimensional speckle tracking image (2D-STI) technique.The circumferential strains radial...

Abstract Background Implantable loop recorders (ILRs) can provide an enhanced possibility to detect atrial fibrillation (AF), but the accuracy, especially positive predictive value (PPV), is controversial. This study aimed evaluate accuracy of ILRs for detecting AF through a comparison with Holter. Method and results Thirteen patients who underwent ablation were enrolled. implanted in all patients, scheduled have Holter monitorings after procedure. The incidence was compared between two...

As COVID-19 spreads worldwide, cardiac injury in patients infected with becomes a significant concern.Thus, this study investigates the impact of several electrocardiogram parameters and disease severity patients.The deceased showed increased dispersion QTc Tpe-c compared surviving (78.2±41.1 vs. 40.8±24.6ms 60.2±37.3vs 40.8±24.5 ms, both p<0.05).The more than 56.1 ms could predict mortality multivariate analysis (Odd ratio 8.06, 95% Confidence Interval 2.843-25.750).A prolonged be an...

Few studies have assessed left ventricular (LV) dyssynchrony in cases of diastolic dysfunction that do not include overt symptoms heart failure. We hypothesized systolic or involves unique features with respect to the degree impairment isolated dysfunction.We examined 105 subjects no history failure and a ejection fraction > 50% for mechanical using tissue Doppler imaging.In terms longitudinal dyssynchrony, four showed (6.3%) LV intraventricular (SDS(LV)), whereas none had (DDS(LV))...

Background and Objectives: The QT interval (QTi) dispersion (QTd), which represent the myocardial electrical heterogeneity of repolarization, were studied to recognize differences between normal controls (n=32) stable angina patients (n=78). Subjects Methods: During treadmill exercise test, standard 12 lead Electrocardiogram (ECG) was obtained at every stage, with QTi QTd measured. corrected (cQTi) (cQTd) calculated using Bazett’s formula, Delta (ΔQTi) measured on leads V5 aVF. Results:...

Atherosclerotic renal artery stenosis (RAS) may result in hypertension, azotemia, and acute pulmonary edema. We report on a angioplasty with stent placement for bilateral RAS patient decompensated heart failure kidney injury. A 67-year-old female was admitted to our hospital shortness of breath generalized Echocardiography showed left ventricular wall motion abnormality the follow up electrocardiography T wave inversion precordial leads. performed coronary angiography differentiate ischemic...

The incidence and importance of tricuspid valve regurgitation after a blunt chest injury has risen with the increase in number automobile accidents steering wheel traumas. This kind been reported more frequently last decade because better diagnostic procedures understanding pathology. However, following can still be easily missed most patients do not show symptoms at time trauma. A 55-year-old male patient presented himself our facility suffering from an accident. His transthoracic...