A5028663574- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Advanced Radiotherapy Techniques
- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal and Anal Carcinomas
- Fungal Biology and Applications
- Neuroendocrine Tumor Research Advances
- Gastric Cancer Management and Outcomes
- Biofuel production and bioconversion
- Enzyme-mediated dye degradation
- Metastasis and carcinoma case studies
- Cancer, Lipids, and Metabolism
- Viral-associated cancers and disorders
- Sarcoma Diagnosis and Treatment
- Peptidase Inhibition and Analysis
- Radiomics and Machine Learning in Medical Imaging
- Colorectal Cancer Surgical Treatments
- Microbial Metabolic Engineering and Bioproduction
- Lymphoma Diagnosis and Treatment
- Head and Neck Anomalies
- Infrared Thermography in Medicine
- Hepatitis B Virus Studies
- Chronic Lymphocytic Leukemia Research
- Inflammatory Biomarkers in Disease Prognosis
- Medical Imaging Techniques and Applications
Hiroshima City Asa Citizens Hospital
2024
North Medical Center
2024
Kure Medical Center
2015-2022
National Hospital Organization
2015-2022
Hiroshima University Hospital
2022
Hiroshima University
2017-2021
Kajima Corporation (Japan)
2020
Okayama University
2017-2019
University of Miyazaki
2014-2018
Nippon Veterinary and Life Science University
2016
Neural circuitry formation depends on the molecular control of axonal projection during development. By screening with fluorophore-assisted light inactivation in developing mouse brain, we identified cartilage acidic protein-1B as a key molecule for lateral olfactory tract (LOT) and named it LOT usher substance (LOTUS). We further Nogo receptor-1 (NgR1) LOTUS-binding protein. NgR1 is receptor myelin-derived axon growth inhibitors, such Nogo, which prevent neural regeneration adult. LOTUS...
Early detection of mild cognitive impairment (MCI) and dementia is very important to begin appropriate treatment promptly prevent disease exacerbation. We investigated the screening accuracy Japanese version Addenbrooke's Cognitive Examination III (ACE-III) diagnose MCI dementia. The original ACE-III was translated adapted Japanese. It then administered a population. Hasegawa Dementia Scale-revised (HDS-R) Mini-mental State (MMSE) were also applied evaluate dysfunction. In total, 389...
Although inflammation-based markers in cancer have been used for prognostic prediction, the most useful marker hepatocellular carcinoma (HCC) has not established. We investigated usefulness of various HCC patients after hepatectomy.A total 478 who underwent initial hepatectomy from 2009 to 2015 and were diagnosed with pathological included this retrospective study. Inflammation-based consisted C-reactive protein albumin ratio (CAR), Glasgow score (GPS), neutrophil lymphocyte ratio, monocyte...
The incidence of bile leakage after liver resection for hepatocellular carcinoma (HCC) remains a cause concern. There are limited reports on the impacts postoperative long-term clinical outcomes. This study aims to evaluate effects recurrence-free survival (RFS) and overall (OS).A total 1,178 patients who underwent curative HCC between 1986 2012 were included in present study. Postoperative was defined using International Study Group Liver Surgery definition, primary end points OS RFS at 5...
Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor. This usually arises as single mass; multicentricity exceptionally rare. We report preoperative diagnosis multicentric SPNs by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). A 32-year-old woman presented to hospital with pancreatic tumor that was detected on abdominal echography. Contrast-enhanced computed tomography (CT) scans revealed 5-mm low-density mass in body and 10-mm tail pancreas. Magnetic...
Abstract Background The white-rot fungus Phlebia sp. strain MG-60 was proposed as a candidate for integrated fungal fermentation process (IFFP), which unifies aerobic delignification and semi-aerobic consolidated biological processing by single microorganism based on its ability to efficiently degrade lignin ferment the sugars from cellulose. To improve IFFP, development of molecular breeding method is necessary. purpose this study establish transformation obtain over-expressing...
Hepatic pseudolymphoma is a very rare benign reactive lymphoid hyperplasia associated with autoimmunity and chronic inflammatory liver diseases such as primary biliary cirrhosis may mimic hepatocellular carcinoma. This diagnosis should be suspected in female suspicious single tumor. Close monitoring needed view of its premalignant nature.
Key Clinical Message Inferior vena cava (IVC) aneurysms are extremely rare. Patients can be asymptomatic, have thrombosis, rupture, or pulmonary embolism. Thrombosis of the IVC aneurysm may mimic a retroperitoneal tumor. Surgical treatment abdominal venous with thrombosis is warranted and necessary for management intraoperative bleeding thrombosis.
Abstract Background The aim of the present study was to clarify treatment outcomes living donor liver procurement using water jet scalpel ( WJS ). Methods This single‐center, retrospective cohort included 40 donors who underwent from January 2014 December 2018. One posterior segmentectomy excluded. Clinical data and after surgery for 20 19 Cavitron Ultrasonic Surgical Aspirator CUSA ) were compared. Results Preoperative excised graft did not differ significantly between groups. Operation...
The object of the present study was to reveal action inosine-5'-monophosphate (IMP) toward myofibrils in postmortem muscles. IMP solubilized isolated actomyosin within a narrow range KCl concentration, 0.19-0.20 mol/L, because dissociation into actin and myosin, but it did not solubilize proteins with 0.2 mol/L KCl. However, could both presence 1 m pyrophosphate or 1.0-3.3 adenosine-5'-diphosphate (ADP). Thus, we presumed that ADP released thin filaments composed actin, thick myosin from...
Methotrexate-associated lymphoproliferative disorder (MTX-LPD) involves lymphoid proliferations or lymphomas in subjects with autoimmune disease, especially rheumatoid arthritis (RA) treated methotrexate (MTX). The relationship of MTX medication and LPD development has been discussed, we report four cases MTX-LPD. Case 1: A 54-year-old woman administered for RA since April 2007 was seen right cheek submandibular swelling August 2008. Magnetic resonance imaging (MRI) showed cervical...
The risk of hepatitis C virus infection-related hepatocellular carcinoma (HCC) is lower, with a better prognosis, in patients who achieve sustained virological response (SVR) than those do not. We aimed to identify factors post-hepatectomy HCC recurrence achieved SVR.This retrospective study included 349 underwent an initial radical hepatectomy at our institution between January 2005 and December 2014. Sixty-eight had SVR (the group) 281 not non-SVR group). Clinical characteristics long-term...
Background Recently, depression with Lewy body pathology before the appearance of parkinsonism and cognitive dysfunction has been drawing attention. Low cardiac metaiodobenzylguanidine (MIBG) uptake is helpful for early differentiation disease (LBD) from late‐onset psychiatric disorders even or dementia appears. In this study, we used MIBG as a tool in suspected LBD, evaluated relationship results to clinical characteristics depressive symptoms. Methods Fifty‐two elderly inpatients were...
Abstract Aim We previously reported that abdominal aortic calcification is associated with poor overall and recurrence‐free survival after hepatectomy for hepatocellular carcinoma (HCC). However, the effect of on cancer‐specific prognosis in very old patients several comorbidities remains unknown. This multicenter study aimed to evaluate impact cumulative recurrence rate HCC aged >80 years. Methods retrospectively analyzed data 128 (aged ≥80 years) who underwent liver resection at seven...