Shuang Hu

ORCID: 0000-0001-8822-7450
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Health Sciences Research and Education
  • Health Policy Implementation Science
  • Endoplasmic Reticulum Stress and Disease
  • Nursing Education, Practice, and Leadership
  • Innovations in Medical Education
  • Genetic factors in colorectal cancer
  • Cancer Genomics and Diagnostics
  • Functional Brain Connectivity Studies
  • Nursing education and management
  • Cancer Immunotherapy and Biomarkers
  • Hepatitis C virus research
  • Liver physiology and pathology
  • Nursing Diagnosis and Documentation
  • Inflammatory Myopathies and Dermatomyositis
  • Land Rights and Reforms
  • Coaching Methods and Impact
  • Educational and Psychological Assessments
  • Immune Cell Function and Interaction
  • Connective Tissue Growth Factor Research
  • Autophagy in Disease and Therapy
  • Optical Imaging and Spectroscopy Techniques
  • Music Therapy and Health
  • Sirtuins and Resveratrol in Medicine
  • Art Therapy and Mental Health

Central South University
2021-2025

Jiangxi Agricultural University
2025

University of Turku
2024

The Seventh Affiliated Hospital of Sun Yat-sen University
2023

Sun Yat-sen University
2022-2023

Second Affiliated Hospital of Nanjing Medical University
2023

University of California, Davis
2021-2022

Anhui Medical University
2019-2022

Changchun University of Chinese Medicine
2022

Changsha Medical University
2021

Nursing professional identity is an important factor in the development of nursing education and clinical practice. Career-planning curriculums enable students to learn relevant knowledge skills a targeted manner, addition achieve career targets. Assessment analysis present situation Chinese students’ planning may provide guidance for improvement teaching content quality career-planning curriculum. This study aimed describe identity, find out influences planning, internship experience, other...

10.1016/j.nedt.2021.104781 article EN cc-by-nc-nd Nurse Education Today 2021-01-20

Abstract Background The central component in impactful healthcare decisions is evidence. Understanding how nurse leaders use evidence their own managerial decision making still limited. This mixed methods systematic review aimed to examine used solve leadership problems and describe the measured perceived effects of evidence-based on performance, organizational, clinical outcomes. Methods We included articles using any type research design. referred nurses, managers or other nursing staff...

10.1186/s12912-024-02096-4 article EN cc-by BMC Nursing 2024-07-03

Bipolar depression (BD) is a unique, severe and prevalent mental illness that shares many similarities in symptoms with unipolar (UD). Improving precision of their diagnoses would enhance treatment outcome prognosis for both conditions. This study aims to provide evidence from functional Near-Infrared Spectroscopy (fNIRS) as potential tool differentiate UD BD based on differences hemodynamic change the prefrontal cortex during verbal fluency tasks (VFT). We enrolled 179 participants...

10.1016/j.jad.2020.12.048 article EN cc-by-nc-nd Journal of Affective Disorders 2020-12-16

Background: Assessing the magnitude of total cancer burden due to smoking and secondhand smoke is imperative for formulation impactful prevention mitigation strategies. Utilizing findings from 2021 Global Burden Diseases, Injuries, Risk Factors Study (GBD), this analysis informs evidence-based planning control tobacco regulation initiatives at national international levels.Methods: As part GBD, we analyzed two pairs risk-outcome combinations estimate smoking- second-hand smoke-attributable...

10.2139/ssrn.5085574 preprint EN 2025-01-01

Cultivated land is the most valuable agricultural resource and important factor of production. The protection cultivated quality not only foundation national food security but also a strategic issue related to sustainable development economy society as whole. This paper uses survey data from Jiangxi Province's "Double Hundred Thousand" in 2023 empirically analyzes impact digital literacy on farmers' behaviors its mechanism by using O-probit model mediating effect model. results show that can...

10.1371/journal.pone.0319050 article EN cc-by PLoS ONE 2025-02-27

Despite the abundance of existing literature on evidence-based nursing practice, knowledge regarding leadership, that is, leadership supported by an approach, is lacking. Our aim to conduct a mixed-methods systematic review with qualitative and quantitative studies examine how evidence used solve problems describe measured perceived effects nurses nurse leaders their performance as well organisational clinical outcomes.

10.1136/bmjopen-2021-055356 article EN cc-by-nc BMJ Open 2021-10-01

Abstract Transmembrane protein 88 (TMEM88) is a potential 2‐transmembrane‐type that interacts with the PDZ domain of Dishevelled‐1 (DVL‐1), crucial component Wnt signalling pathway through its C‐terminal Val‐Trp‐Val (VWV) motif in Xenopus embryo cells. Since significant function β‐catenin liver fibrosis, it urgent to study TMEM88 mechanism fibrosis. The current research was for evaluating process fibrosis and clarifying inherent mechanism. found decreased human fibrotic tissues....

10.1111/jcmm.15119 article EN cc-by Journal of Cellular and Molecular Medicine 2020-05-28

Non-alcoholic fatty liver disease (NAFLD) is a major health problem in Western countries and has become the most common cause of chronic disease. Although NAFLD closely associated with obesity, inflammation, insulin resistance, its pathogenesis remains unclear. The begins excessive accumulation triglycerides liver, which turn leads to cell damage, steatosis, so on. P38γ one four isoforms P38 mitogen-activated protein kinases (P38 MAPKs) that contributes inflammation different diseases. In...

10.1096/fj.202200939rr article EN The FASEB Journal 2022-12-17

Background Although many efforts have been devoted to identify biomarkers predict the responsiveness of immune checkpoint inhibitors, including expression programmed death-ligand 1 (PD-L1) and major histocompatibility complex (MHC) I, microsatellite instability (MSI), mismatch repair (MMR) defect, tumor mutation burden (TMB), tertiary lymphoid structures (TLSs), several transcriptional signatures, sensitivity these indicators remains be further improved. Materials methods Here, we integrated...

10.3389/fimmu.2023.1142862 article EN cc-by Frontiers in Immunology 2023-04-28

Introduction This study protocol describes two randomised feasibility trials that will evaluate the and preliminary effectiveness of an online training course to improve evidence-based leadership competences among nurse leaders working in hospitals Finland China. Methods analysis Two randomised, parallel-group studies be conducted separately: one (n=140) China (n=160). Nurse who fulfil eligibility criteria randomly allocated (1:1) participate either or conventional (reading material only)....

10.1136/bmjopen-2022-067306 article EN cc-by-nc BMJ Open 2023-08-01

Objective To evaluate the feasibility of an online evidence-based leadership training programme for nurse leaders and its potential effectiveness in improving leaders’ competencies. Design This is a two-arm, parallel, randomised controlled trial. Methods We screened all 160 from two Chinese hospitals. Eligible participants who gave their informed consent were randomly assigned to either group or conventional at each site received 7-month intervention. Pre-test post-test assessments gauged...

10.1136/bmjopen-2024-088386 article EN cc-by-nc-nd BMJ Open 2024-11-01

A 70-year-old man with lung cancer underwent whole-body MDP bone scintigraphy to evaluate metastases that showed marked tracer uptake in the right side of head, suggestive skull metastasis. SPECT/CT imaging was performed for further evaluation. The SPECT images demonstrated increased activity region brain perfused by middle cerebral artery. On CT images, there a large hypoattenuation area corresponding elevated accumulation. At same day, magnetic resonance angiography revealed occlusion

10.1097/rlu.0000000000000225 article EN Clinical Nuclear Medicine 2013-10-02

This study aimed to establish optimal surgical strategies via reviewing the clinical outcomes of various approaches for pertroclival meningiomas (PCMs).This retrospective enrolled 107 patients with PCMs at authors' institution from year 2010 2020. Patient demographics, characteristics, operative approaches, major morbidity, post-operative cranial nerve deficits and tumor progression or recurrence were analyzed.The subtemporal transtentorial approach (STA), Kawase (KA), retrosigmoid (RSA)...

10.3389/fonc.2021.761284 article EN cc-by Frontiers in Oncology 2021-11-22

Several studies have linked myosteatosis with nonalcoholic fatty liver disease (NAFLD) in individuals obesity. The clinical significance of NAFLD the general population has not been well investigated. Here, we wanted to explore and compare associations fibrosis muscle fat content skeletal mass (SMM) a relatively large China.

10.1007/s12603-023-2015-9 article EN cc-by-nc-nd The journal of nutrition health & aging 2023-10-31

Exhaled breath condensate (EBC) is routinely collected and analyzed in research. Because it contains aerosol droplets, EBC samples from SARS-CoV-2 infected individuals harbor the virus pose threat of infectious exposure. We report for first time a safe consistent method to fully inactivate make processing analysis. containing were treated with several concentrations acetonitrile. The most commonly used 10% acetonitrile treatment failed completely viable was detected by assay infection Vero...

10.1088/1752-7163/ac3f24 article EN Journal of Breath Research 2021-12-01

Abstract Objective To recognize risk factors and build up validate a simple model predicting 8‐year cancer events after nonalcoholic fatty liver disease (NAFLD). Methods This was retrospective cohort study. Patients with NAFLD (n = 5561) were randomly divided into groups: training 1254), test 627), evaluation validation 3053). Risk recognized by statistical method named as Cox Markov chain Monte Carlo (MCMC) simulation. prediction score established based on the group further validated...

10.1002/cam4.2777 article EN cc-by Cancer Medicine 2019-12-20
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