- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Screening and Detection
- Genetic factors in colorectal cancer
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Gallbladder and Bile Duct Disorders
- Cervical Cancer and HPV Research
- Extracellular vesicles in disease
- Renal Diseases and Glomerulopathies
- Medieval European History and Architecture
- Colorectal and Anal Carcinomas
- Colorectal Cancer Treatments and Studies
- Chromatography in Natural Products
- Pelvic floor disorders treatments
- Liver Disease Diagnosis and Treatment
- Enterobacteriaceae and Cronobacter Research
- Gut microbiota and health
- Hepatocellular Carcinoma Treatment and Prognosis
- Histiocytic Disorders and Treatments
Instituto Português de Oncologia Francisco Gentil
2019-2024
University of Trás-os-Montes and Alto Douro
2024
IPO Porto
2019-2023
University Gastroenterology
2020
Universidade do Porto
2019
Main Recommendations MR1 ESGE recommends the following standards for Barrett esophagus (BE) surveillance: – a minimum of 1-minute inspection time per cm BE length during surveillance endoscopy photodocumentation landmarks, segment including one picture length, and esophagogastric junction in retroflexed position, any visible lesions use Prague (for lesions) Paris classification collection biopsies from all abnormalities (if present), followed by random four-quadrant every 2-cm length. Strong...
Objectives To assess the value of endoscopic grading gastric intestinal metaplasia (EGGIM), operative link on gastritis assessment (OLGA) and (OLGIM) risk stratification for early neoplasia (EGN) to investigate other factors possibly associated with its development. Design Single centre, case–control study including 187 patients EGN treated endoscopically age-matched sex-matched control subjects. Individuals were classified according EGGIM, OLGA OLGIM systems. stages clinical parameters was...
Endoscopic submucosal dissection (ESD) is a treatment for early gastric neoplasms that preserves the stomach. However, risk of multiple lesions persists.To assess clinicopathologic characteristics patients with in Western country and evaluate factors lesions, synchronous, or metachronous.A retrospective cohort 230 consecutive who underwent ESD primary from 2012 to 2017 (median follow-up: 33 months) was assessed determine lesions.The mean age 68 years, 53.9% were male. Current/former smoking...
Multiple guidelines on Barrett's esophagus (BE) have being published in order to standardize and improve clinical practice. However, studies shown poor adherence them. Our aim was synthetize, compare, assess the quality of recommendations from recently guidelines, stressing similarities differences. We conducted a search Pubmed Scopus. When different same society were identified, most recent one considered. used GRADE system evidence. included 24 position/consensus statements European...
Background Identification of Barrett’s esophagus (BE) with the treatment dysplasia is essential to prevent esophageal adenocarcinoma (EAC). Moreover, determination BE prevalence important define subsequent management strategies. However, precise estimates on from several European countries are lacking. We aimed determine in a Southern country. Methods A cross-sectional, multicenter study November 2019 February 2020 was performed defining as columnar extent distal greater than or equal 1 cm...
Introduction: Surveillance of Lynch syndrome (LS) is recommended to reduce cancer-risk. There an increased awareness that cancer-risk may vary with mismatch-repair mutation and family history. However, gene-specific family-specific surveillance are not recommended. Therefore, we aimed estimate the cumulative incidence lesions assess by history (MMR).Methods: Single-centre retrospective cohort all individuals (n = 241) in a specialized institution was conducted.Results: Forty-eight percent...
Endoscopic retrograde cholangiopancreatography (ERCP) in patients with Billroth II gastrectomy is still a challenging procedure. The optimal approach, namely the type of endoscope and sphincter management, has yet to be defined.To compare efficacy safety forward-viewing gastroscope side-viewing duodenoscope ERCP gastrectomy.We conducted retrospective, single-center cohort study consecutive submitted an expert center for between 2005 2021. outcomes assessed were: papilla identification, deep...
Introduction The cumulative lifetime risk of gastric cancer (GC) in patients with Lynch syndrome (LS) is reported to be 8%. There limited evidence on specific factors for GC and no agreement among guidelines endoscopic surveillance schedule LS patients. Aims methods We conducted a retrospective cohort study identify precancerous conditions (chronic atrophic gastritis intestinal metaplasia) case–control compare the prevalence these control group. Results included 385 (40.5% male, mean age...
Edible mushrooms have been considered an excellent source of nutraceuticals with high potential to prevent diseases such as cancer. Recently the anti-cancer a small RNA (sRNA) fraction isolated from C. cibarius was described. To better understand its molecular nature, study carried out regarding sRNAs different mushroom species. Apart isolation RNA-rich fractions by anion exchange chromatography, miRNA's extraction also using commercial kit. The anti-proliferative activity samples tested in...
Renovascular hypertension is a cause of secondary hypertension. Atherosclerotic renal artery stenosis and fibromuscular dysplasia are the main causes, but other rare entities can involve arteries. Erdheim-Chester disease non-Langerhans cell histiocytosis with heterogenous clinical presentation prognosis. We report case 63-year-old woman history Langerhans presenting difficult-to-treat A literature review presented, owing to pathophysiology anatomical characteristics vascular attainment, we...
The authors disclose no conflict.
A 72-year-old woman with long-term dyspepsia underwent an outpatient upper gastrointestinal endoscopy, which showed a large pedunculated polypoid lesion of 30 mm on the lesser curvature gastric body ([Fig. 1 a]). As endoscopic biopsies tubulovillous adenoma low grade dysplasia, patient was referred to hospital for resection. Pre-procedural reassessment using virtual chromoendoscopy (narrow-band imaging [NBI]) revealed areas irregular glandular and vascular pattern in pedicle surrounding...
Marques-de-Sá, Inês MD1; Pita, Coimbra, Nuno MD2; Dinis-Ribeiro, Mário PhD1,3 Author Information
Aims Both the incidence for Barrett’s esophagus (BE) and gastro-esophageal junction (GEJ) tumors seems to be increasing. Interestingly, patients with intestinal metaplasia (IM) affecting distal (eg BE) or at GEJ are managed in opposite directions, follow-up being mandatory former absence of further care recommended later. Also, management superficial lesions depends on presence BE, EMR ESD suggested, respectively. We aimed determine clinical features prevalence premalignant conditions...