A5031468085- Cerebrovascular and Carotid Artery Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic aneurysm repair treatments
- Cardiovascular Health and Disease Prevention
- Peripheral Artery Disease Management
- Vascular Procedures and Complications
- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Inflammatory Biomarkers in Disease Prognosis
- Aortic Disease and Treatment Approaches
- Venous Thromboembolism Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- COVID-19 and healthcare impacts
- Renal and Vascular Pathologies
- Palliative Care and End-of-Life Issues
- Diagnosis and Treatment of Venous Diseases
- Cardiovascular Disease and Adiposity
- Childhood Cancer Survivors' Quality of Life
- Cardiac Valve Diseases and Treatments
- Vascular anomalies and interventions
- Patient Satisfaction in Healthcare
- Infectious Aortic and Vascular Conditions
- Pain Management and Opioid Use
- Antibiotic Use and Resistance
- Hip and Femur Fractures
Centre for Health Technology and Services Research
2024-2025
Universidade do Porto
2015-2025
Hospital de São João
2015-2024
Administração Regional de Saúde de Lisboa e Vale do Tejo
2024
Health and Care Research Wales
2022
Hospitais da Universidade de Coimbra
2018
Centro Hospitalar do Porto
2014
Centro Hospitalar de Vila Nova de Gaia
2010-2011
Philadelphia University
1984
Abstract Purines are important modulators of bone cell biology. ATP is metabolized into adenosine by human primary osteoblast cells (HPOC); due to very low activity deaminase, the nucleoside end product ecto‐nucleotidase cascade. We, therefore, investigated expression and function receptor subtypes (A 1 , A 2A 2B 3 ) during proliferation osteogenic differentiation HPOC. Adenosine (CPA), (CGS21680C), (NECA), (2‐Cl‐IB‐MECA) agonists concentration‐dependently increased HPOC proliferation....
Cancer pain is a highly prevalent problem and one of the most distressing symptoms in cancer patients. The management significant challenges care these must be treated quickly effectively as it affects quality life reduces patient’s expectancy. Major opioids are recognized by World Health Organization (WHO) first-line treatment for moderate to severe pain, but their use often hampered individual variations, comorbidities, complications associated with cancer. Since simultaneous two major has...
BACKGROUND: Aortoiliac disease poses a significant cardiovascular (CV) risk, especially in individuals with chronic kidney disease. This study aimed to assess the predictive role of long-term major adverse CV events patients submitted aortoiliac revascularization due severe atherosclerotic disease.METHODS: From 2013 2023, who underwent for TASC II type D lesions, including those disease, were selected from prospective cohort study. Demographic, clinical, and postoperative data collected....
Introduction: Percutaneous endoscopic gastrostomy (PEG) placement does not generate consensus in palliative care, given the existing doubts about whether it significantly contributes to an improvement patient outcomes such as survival, quality of life and symptomatic control. Objective: This study explored impact percutaneous on survival patients under community care Northern Portugal. Methods: observational, retrospective cohort involved 54 monitored by a specialized team between March 2020...
Abstract This study aimed at investigating the expression and function of uracil nucleotide‐sensitive receptors (P2Y 2 , P2Y 4 6 ) on osteogenic differentiation human bone marrow stromal cells (BMSCs) in culture. Bone specimens were obtained from postmenopausal female patients (68 ± 5 years old, n = 18) undergoing total hip arthroplasty. UTP UDP (100 µM) facilitated measured as increases alkaline phosphatase (ALP) activity, without affecting cell proliferation. Uracil nucleotides...
Objective To summarize characteristics, complications, and success rates of different catheter-directed thrombolysis (CDT) protocols for the treatment lower extremity deep venous thrombosis (LE-DVT). Methods A systematic review using electronic databases (MEDLINE, Scopus, Web Science) was performed to identify randomized controlled trials observational studies related LE-DVT treated with CDT. random-effects model meta-analysis obtain pooled proportions early postthrombotic syndrome (PTS),...
Abstract Background Decision-making when considering major lower limb amputation is complex and requires individualized outcome estimation. It unknown how accurate healthcare professionals or relevant prediction tools are at predicting outcomes 1-year after amputation. Methods An international, multicentre prospective observational study evaluating professional accuracy in 1 year evaluation of identified a systematic search the literature was undertaken. Observed were compared with:...
Compare technical, clinical, and economic outcomes between endovascular open approaches in patients with type D aortoiliac occlusive disease according to the TransAtlantic Inter-Society Consensus.Patients undergoing revascularization for lesions, either or surgery approach, from 2 Portuguese institutions January 2011 October 2017 were included. The surgical technique was left surgeon discretion. Patients common femoral artery affection, both obstructive aneurysmatic, excluded.Twenty-seven...
Vascular compression syndromes (VCS) are rare diseases, but they may cause significant symptoms interfering with the quality of life (QoL) patients who often in their younger age. Given infrequent occurrence, multiform clinical and anatomical presentation, absence dedicated guidelines from scientific societies, further knowledge these conditions is required to investigate treat them using modern imaging surgical (open or endovascular) techniques. This consensus document will focus on known...