A5029601601- Autism Spectrum Disorder Research
- Family and Disability Support Research
- Language Development and Disorders
- Child Development and Digital Technology
- Genetics and Neurodevelopmental Disorders
- Phonetics and Phonology Research
- Virology and Viral Diseases
- Child and Adolescent Psychosocial and Emotional Development
- Reading and Literacy Development
- Infant Development and Preterm Care
- Stuttering Research and Treatment
- Psychosocial Factors Impacting Youth
- Obsessive-Compulsive Spectrum Disorders
- Infant Health and Development
- Neurobiology of Language and Bilingualism
- Attention Deficit Hyperactivity Disorder
- CRISPR and Genetic Engineering
- Infection Control and Ventilation
- Vaccine Coverage and Hesitancy
- Mental Health and Psychiatry
- Fetal and Pediatric Neurological Disorders
- Atomic and Subatomic Physics Research
- ICT in Developing Communities
- Child Nutrition and Feeding Issues
- Hearing Loss and Rehabilitation
National Institute of Mental Health and Neurosciences
2012-2024
University of North Carolina at Chapel Hill
2019-2020
The way that parents communicate with their typically developing infants is associated later infant language development. Here we aim to show these associations are observed in subsequently diagnosed autism spectrum disorder (ASD). This study had three groups: high‐familial‐risk who did not have ASD ( n = 46); 14); and low‐familial‐risk exhibited typical development 36). All‐day home recordings were collected at 9 15 months, skills assessed 24 months. Across all the study, including those...
Emerging evidence suggests parenting supports implemented in the first 2 years of life may influence developmental outcomes for infants more likely to be Autistic. Yet questions remain about acceptability these Autistic and autism communities. Through mixed-methods participatory research – co-designed produced by non-Autistic researchers we sought diverse community perspectives on this topic, including understand relative different support options. A total 238 participants completed our...
Abstract Background Canonical babbling—producing syllables with a mature consonant, full vowel, and smooth transition—is an important developmental milestone that typically occurs in the first year of life. Some studies indicate delayed or reduced canonical babbling infants at high familial likelihood for autism spectrum disorder (ASD) who later receive ASD diagnosis, but evidence is mixed. More refined characterization life needed. Methods Vocalizations produced 6 12 months by ( n = 267)...
Abstract Background Younger siblings of children with autism spectrum disorder (ASD) are at increased likelihood receiving an ASD diagnosis and exhibiting other developmental concerns. It is unknown how quantitative variation in traits broader domains older (probands) may inform outcomes their younger siblings. Methods Participants included 385 pairs toddler probands from the Infant Brain Imaging Study. (mean age 5.5 years, range 1.7 to 15.5 years) were phenotyped using Autism Diagnostic...
Infant vocalizations are early-emerging communicative markers shown to be atypical in autism spectrum disorder (ASD), but few longitudinal, prospective studies exist. In this study, 23,850 infant from infants at low (LR)- and high (HR)-risk for ASD (HR-ASD = 23, female 3; HR-Neg 35, 13; LR 32, 10; 80% White; collected 2007 2017 near Philadelphia) were analyzed 6, 12, 24 months. At 12 months, HR-ASD produced fewer than infants. From 6 demonstrated steeper vocalization growth compared Finally,...
Background Diagnostic shifts at early ages may provide invaluable insights into the nature of separation between autism spectrum disorder (ASD) and typical development. Recent conceptualizations ASD suggest condition is only fuzzily separated from non‐ASD, with intermediate cases two. These shift along a transition region over time, leading to apparent instability diagnosis. Methods We used cohort children high risk, by virtue having an older sibling ASD, assessed 24 months ( N = 212) 36...
Decades of research have established that the home language environment, especially quality caregiver speech, supports acquisition during infancy. However, neural mechanisms behind this phenomenon remain under studied. In current study, we examined associations between environment and structural coherence white matter tracts in 52 typically developing infants from English speaking homes a western society. Infants participated at least one MRI brain scan when they were 3, 6, 12, and/or 24...
The broad autism phenotype (BAP) is a set of characteristics often observed in typically developing people with genetic load for autism, such as parents autistic children. Broad Autism Phenotypic Questionnaire (BAPQ) 36-item questionnaire developed to identify the BAP first-degree relatives people. We translated BAPQ into Swedish and examined its psychometric properties sample consisting 45 children ASC 74 non-autistic found support original 3-factor structure (aloof, pragmatic language...
Abstract Background and Objectives: Broad Autism Phenotype (BAP) refers to specific behaviors or minor deficits in social/communication skills not meeting the diagnostic criteria for autism spectrum disorders (ASDs). The BAP Questionnaire (BAPQ) measures aloof personality (AP), rigid (RP), pragmatic language (PL) of BAP. study objective is translate validate BAPQ into Malayalam, a South Indian language, establish new cut-off scores detecting population. Methods: was translated Malayalam...
Preliminary evidence indicates potential benefit of providing caregiver-mediated intervention, prior to diagnosis, for infants at elevated familial likelihood autism and related developmental delays including language delay (EL-A). However, delivering such interventions online in low-resource settings like India has not been reported. This study aimed evaluate the feasibility acceptability a novel manualized early support program, "LiL' STEPS," India, EL-A infants. LiL' STEPS stands Language...
Purpose: The Language ENvironment Analysis (LENA) technology uses automated speech processing (ASP) algorithms to estimate counts such as total adult words and child vocalizations, which helps understand children's early language environment. This ASP has been validated in North American English other languages predominantly monolingual contexts but not a multilingual context like India. Thus, the current study aims validate classification accuracy of LENA algorithm specifically focusing on...
The last decade has seen a rise in big data approaches, including the humanities, whereby large quantities of are collected and analysed. In this paper, we discuss long-form audio recordings that result from individuals wearing recording device for many hours. Linguists, psychologists anthropologists can use them, example, to study infants’ or adults’ linguistic behaviour. past, recorded communities have resided high-income countries (HICs) almost exclusively. Recognising need better...
Abstract India is a socioculturally and linguistically diverse country. Most often individuals grow up exposed to more than one language. Apart from exposure native community languages, there growing preference for English as the language of formal education employment. Previous studies demonstrated that bilingual children with autism spectrum disorder (ASD) develop similar their monolingual nonverbal IQ-matched ASD peers. However, most these have been conducted in countries which primary...
The early emergence of social communication challenges and their impact on language in infants later diagnosed with autism has sparked many intervention programs that target skills. While research consistently shown lower scores assessments the first year life, there is limited at 12-months exploring associations between different dimensions language. Understanding skills would enhance our ability to choose high priority goals will downstream current study used a standardized assessment...
Researchers have reported a higher prevalence for parents of children with autism spectrum disorders (ASD) to subtle characteristics ASD, known as the broad phenotype (BAP). Deficits in pragmatics language are hallmark feature ASD and thus become natural candidate assessment BAP. This study focused on pragmatic impairments from India, group that is ethnically socio-culturally different west. Pragmatics was assessed using questionnaire along directly observing, recording, profiling social...