Beata Pyrżak

ORCID: 0000-0001-8914-7815
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About
Contact & Profiles
Research Areas
  • Growth Hormone and Insulin-like Growth Factors
  • Adipokines, Inflammation, and Metabolic Diseases
  • Thyroid Disorders and Treatments
  • Obesity, Physical Activity, Diet
  • Diabetes and associated disorders
  • Adipose Tissue and Metabolism
  • Birth, Development, and Health
  • Vitamin D Research Studies
  • Regulation of Appetite and Obesity
  • Diet and metabolism studies
  • Digestive system and related health
  • Pancreatic function and diabetes
  • Sexual Differentiation and Disorders
  • Diabetes Management and Research
  • Childhood Cancer Survivors' Quality of Life
  • Lipid metabolism and disorders
  • Adrenal Hormones and Disorders
  • Immune Cell Function and Interaction
  • Asthma and respiratory diseases
  • Bone health and osteoporosis research
  • T-cell and B-cell Immunology
  • Nutrition and Health Studies
  • Bone Metabolism and Diseases
  • Genetics and Neurodevelopmental Disorders
  • Diabetes, Cardiovascular Risks, and Lipoproteins

Medical University of Warsaw
2015-2024

Children's Hospital
2020

Instytut Matki i Dziecka
2016-2017

Background Obesity is related to changes in adipokine secretion, activity of adipose tissue macrophages, helper T cells, and regulatory cells. It has been confirmed that vitamin D potent anti-inflammatory properties. contributes reduction pro-inflammatory mediators an increase cytokines. There also evidence could decrease C-reactive protein (CRP) affect selected haematological indices. Aim the Study We aimed evaluate effect on interleukin (IL)-10, IL-17, CRP, blood leukocyte profile,...

10.3389/fendo.2022.920340 article EN cc-by Frontiers in Endocrinology 2022-06-13

The triglycerides to high-density lipoprotein cholesterol ratio (TG/HDL-C) is a useful surrogate marker of insulin resistance and cardiovascular risk factors. We aimed assess the relationship between TG/HDL-C (IR) its usefulness in prediction metabolic syndrome (MS). This retrospective study involved 122 obese children with mean age 11.6±3 years their 58 healthy lean peers. Anthropometric measurements, blood pressure, plasma lipid profile oral glucose tolerance test (OGTT) were analyzed....

10.18388/abp.2018_2649 article EN cc-by Acta Biochimica Polonica 2018-11-19

Abstract Background The incidence of childhood type 1 diabetes (T1D) varies greatly between populations, and the estimates and/or predictions rates would aid in adequate planning health care resources. study's aim was to assess T1D paediatric population eastern central Poland. Methods In this cohort study covering period from January 2010 December 2014, data were collected for children adolescents below 18 years age with newly diagnosed living A total 2174 included analysis. Central...

10.1002/dmrr.2962 article EN Diabetes/Metabolism Research and Reviews 2017-11-16

Introduction: The diagnostic value of the level TSH receptor antibodies (TSHR-Ab) in population children with autoimmune thyroid diseases (AITDs) is still unknown. aim this cross-sectional study was to investigate prevalence TSHR-Ab a paediatric cohort AITD and healthy controls.Materials methods: A total 240 serum samples were obtained from 205 patients AITD, type 1 diabetes (T1D), juvenile arthritis (JA), controls (C). TSHR stimulating (TSI) -blocking (TBI) immunoglobulins measured...

10.1080/08916934.2018.1431776 article EN Autoimmunity 2018-01-26

Abstract Background Atrophic autoimmune thyroiditis (AAT) is a rare phenotype of (AT) in pediatric age. AAT occurs without thyroid enlargement leading to delay its diagnosis. Growth impairment infrequent thyroiditis, if timely diagnosed. Prolonged severe hypothyroidism cause pituitary hyperplasia (PH) childhood. Loss thyroxine negative feedback causes TRH-dependent thyrotroph cells resulting adenohypophysis enlargement. A transdifferentiation somatotroph into could explain growth failure...

10.1186/s13052-024-01641-w article EN cc-by ˜The œItalian Journal of Pediatrics/Italian journal of pediatrics 2024-04-23

Diabetes and Nephrotic syndrome (NS) promote plaque-related gingivitis yeast-like fungal infections. The study assesses the impact of Candida spp. general disease- or treatment-related factors on severity in children adolescents with /diabetes.Body mass index (BMI), BMI standard deviation score, oral cavity (Plaque Index--PLI, Gingival Index--GI, mucosa status, presence enzymatic activity) were assessed 96 patients (32 NS: 30- immunosuppressive treatment, 35--type 1 diabetes, 29 generally...

10.1186/s12903-015-0042-6 article EN cc-by BMC Oral Health 2015-05-07

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Majcher A, Czerwonogrodzka-Senczyna KÄ dziela K, Rumińska M, Pyrżak B. Development of obesity from childhood to adolescents. Pediatric Endocrinology Diabetes and Metabolism. 2021;27(2):70-75. doi:10.5114/pedm.2021.105297. APA Majcher, A., Czerwonogrodzka-Senczyna, dziela, K., Rumińska, M., & Pyrżak, (2021). Metabolism, 27(2), 70-75. https://doi.org/10.5114/pedm.2021.105297 Chicago Anna, Aneta Katarzyna...

10.5114/pedm.2021.105297 article EN Pediatric Endocrinology Diabetes and Metabolism 2021-01-01

Neonatal hyperthyroidism mainly occurring in the children born to mothers with Graves' disease (GD). The influence of maternal GD on newborn's thyroid function includes not only hyperthyroidism, but also various forms hypothyroidism. Maternally transferred thyrotropin receptor antibodies (TRAb), antithyroid drug (ATD) administration during pregnancy and previous definitive treatment (radioactive iodine therapy or thyroidectomy) mother impact fetal/neonatal thyroid. Some newborns may present...

10.3389/fendo.2022.877119 article EN cc-by Frontiers in Endocrinology 2022-05-04

The relationships between bone turnover, the growth hormone/insulin-like factor-1 (GH/IGF-1) axis and vitamin D are complex, but still not fully explained. GH/IGF-1 can mutually modulate each other's metabolism influence activation of cell proliferation, maturation, mineralization as well resorption. aim this study was to evaluate reciprocal associations formation markers [alkaline phosphatase (ALP), alkaline (BALP)], 25-hydroxyvitamin [25(OH)D] in children with hormone deficiency at...

10.18388/abp.2017_2541 article EN cc-by Acta Biochimica Polonica 2018-04-12

Despite its characteristic symptoms, type 1 diabetes (T1D) is still diagnosed late causing the development of diabetic ketoacidosis (DKA). The aim this study was to estimate incidence DKA and factors associated with acidosis at T1D recognition in Polish children aged 0-17.The population consisted 2100 newly years 2010-2014 7 hospitals eastern central Poland. living these areas accounts for 35% population. defined as a capillary pH < 7.3, blood glucose > 11 mmol/L. analyzed data included age,...

10.1111/pedi.12446 article EN Pediatric Diabetes 2016-10-11
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