A5100524032- Circular RNAs in diseases
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Sarcoma Diagnosis and Treatment
- MicroRNA in disease regulation
- Prenatal Screening and Diagnostics
- Heart Rate Variability and Autonomic Control
- Power Systems and Renewable Energy
- Building Energy and Comfort Optimization
- Cardiac tumors and thrombi
- RNA Research and Splicing
- Bone Metabolism and Diseases
- Genomic variations and chromosomal abnormalities
- Power Systems and Technologies
- Cardiovascular and exercise physiology
- Microgrid Control and Optimization
- Electric Power Systems and Control
- Cancer-related cognitive impairment studies
- Winter Sports Injuries and Performance
- Radiomics and Machine Learning in Medical Imaging
- Dementia and Cognitive Impairment Research
- Advanced Control Systems Optimization
- Advanced Data Processing Techniques
- Bone fractures and treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
Central South University
2016-2025
Second Xiangya Hospital of Central South University
2016-2025
AdventHealth Orlando
2024-2025
Jiangxi Maternal and Child Health Hospital
2023-2025
Weatherford College
2025
First Affiliated Hospital of Anhui Medical University
2023-2025
Anhui Medical University
2023-2025
Huazhong University of Science and Technology
2025
University of Pittsburgh
2023-2024
Shenzhen University
2024
Osteoblastic bone formation and osteoclastic resorption dynamically maintain the homeostasis; in present study, we attempt to investigate mechanism of excessive activation osteoclasts inducing deregulation homeostasis from perspective non-coding RNA regulation. Differentially expressed patterns circRNAs were examined non-treated RANKL + CSF1-treated marrow monocyte/macrophage (BMM) cells differentially-expressed miRNAs during osteoclast differentiation analyzed identified. We found that...
To evaluate the association between cardiorespiratory fitness (CRF) and cognition in a large sample of older adults, to examine clinical demographic factors that might moderate these associations.
ABSTRACT Introduction This study aimed to assess the incidence of adverse events (AE) in older adults participating a yearlong exercise intervention, investigate potential dose–response relationships between duration and AE frequency, identify demographic factors associated with risk. Methods A total 648 were randomized into one three groups: low-intensity stretching toning (S&T), 150 min aerobic per week (150Ex), or 225 (225Ex). Adverse tracked during event rates calculated based on...
Nonsuicidal self-injury (NSSI) is a major public health problem leading to psychological problems in adolescents and young adults, similar disorders such as depression anxiety. The aims of this study were investigate (1) the interaction between BMI socioenvironmental factors (including chronotype mental health) that contribute NSSI, (2) whether self-esteem plays mediating role association. From May June 2022, multistage cluster sampling method was used sample college students four grades,...
This study was aimed to identify a rare complex rearrangement and assist prenatal counseling. Mate-pair sequencing (MPseq) combined with karyotypes, copy number variants whole exome used provide accurate chromosome breakpoints diagnosis for mentally retarded pregnant woman. MPseq indicated involved 25 fusions, disrupting 6 genes. Among which, ZMIZ1 associated neurodevelopmental disorders dysmorphic facies distal skeletal abnormalities, which consistent the phenotype of women. cost-effective...
Primary bone tumors (PBTs) present significant diagnostic challenges due to their heterogeneous nature and similarities with infections. This study aimed develop an ensemble deep learning framework that integrates multicenter radiographs extensive clinical features accurately differentiate between PBTs We compared the performance of model four imaging models based solely on utilizing EfficientNet B3, B4, Vision Transformer, Swin Transformers. The patients were split into external dataset (N...
Different tasks of episodic memory (EM) are only moderately correlated with each other. Furthermore, various EM exhibit disproportional relationships the hippocampus. This study examined covariance structure and assessed whether this relates differently to hippocampal volume (HV) in a sample 648 cognitively unimpaired older adults (mean age = 69.88). A confirmatory factor analysis (CFA) linear regression models were used test associations between observed factors HV. model three first-order...
Abstract We report the synthesis of bis(hydroxylmethylfurfuryl)amine (BHMFA) from 5‐hydroxymethylfurfural (5‐HMF) by reacting 5‐HMF with primary amines in presence homogeneous Ru II catalysts having sterically strained ligands. BHMFA is a group furan‐based monomers that offer great potential to form functional biopolymers tunable properties. A range amines, such as aliphatic and benzyl are readily converted corresponding good yields. The reaction proceeds through reductive amination amine...
The study was focussed on the inhibitory mechanism associated with ability of an endophytic bacterium - Bacillus altitudinis Q7, obtained from Ginkgo biloba, to inhibit growth Alternaria alternata in vitro. A fungus, identified as isolated rotten part apple. One endophytes Q7. Effect Q7 characterized by measuring membrane permeability and lipid peroxidation. Antioxidant enzymes were determined before after exposure Results indicated that cell membranes damaged, peroxidation enhanced,...
Carnosol is a phytopolyphenol (diterpene) found and extracted from plants of Mediterranean diet, which has anti-tumor, anti-inflammatory antioxidant effects. However, its role in ischemic stroke not been elucidated.Primary neurons subjected to oxygen-glucose deprivation (OGD) was used investigate the effect carnosol vitro. A mouse MCAO model evaluate on vivo. The mRNA level inflammatory apoptosis-related genes determined by RT-PCR. protein total phosphorylated AMPK WB. H&E Immunofluorescent...
Background Autoimmune thyroid disease (AITD) is induced by various factors, including inheritability, which regulates gene expression. Multiple loci correlated with AITD have been discovered utilizing genome-wide association studies (GWASs). Nevertheless, demonstrating the biological relevance and function of these genetic difficult. Methods The FUSION software was utilized to define genes that were expressed differentially in using a transcriptome-wide study (TWAS) method accordance GWAS...
Epilepsy is characterized by recurrent unprovoked seizures. Mutations in the voltage-gated sodium channel alpha subunit 1 (SCN1A) gene are main monogenic cause of epilepsy. Type and location variants make a huge difference severity SCN1A disorder, ranging from mild phenotype (genetic epilepsy with febrile seizures plus, GEFS+) to severe (developmental epileptic encephalopathies, DEEs). Dravet Syndrome (DS) an infantile-onset DEE, drug-resistant temperature sensitivity or Genetic test results...
Fibroblast growth factor (FGF) and tumor factor-β (TGFβ) have emerged as pivotal regulators during the progression of osteosarcoma (OS). LHX9 is one crucial transcription controlled by FGF, however, its function in OS has not been investigated yet.The expression LHX9, FRS2, BMP4, TGF-beta R1, SMAD2, beta-catenin metastasis-related proteins was measured real-time quantitative PCR (RT-qPCR) Western blot. CCK-8 assay colony formation were employed to determine proliferation cells, while scratch...
Abstract Background Pleomorphic liposarcoma is the least common but most aggressive subtype of liposarcoma. Very few studies have presented data on pleomorphic specifically, often including a limited number cases and short-term follow-up. As result, survivorship prognostic characteristics this tumor remain incompletely identified. Study design setting Cross-sectional analysis Surveillance Epidemiology End Results database (1996–2015). Overall survival for entire series was 54% (95%...