A5000729932- Renal and Vascular Pathologies
- Aortic aneurysm repair treatments
- melanin and skin pigmentation
- Primary Care and Health Outcomes
- Genetic Syndromes and Imprinting
- Renal Transplantation Outcomes and Treatments
- Parathyroid Disorders and Treatments
- Silk-based biomaterials and applications
- Cutaneous lymphoproliferative disorders research
- History and advancements in chemistry
- Cutaneous Melanoma Detection and Management
- Innovations in Medical Education
- Alcoholism and Thiamine Deficiency
- Neurological and metabolic disorders
- Wound Healing and Treatments
- Dermatologic Treatments and Research
- Renal Diseases and Glomerulopathies
- Various Chemistry Research Topics
- Immunotherapy and Immune Responses
- Complement system in diseases
- Metabolism and Genetic Disorders
- Chemistry and Chemical Engineering
- Medical Imaging and Pathology Studies
Newcastle University
2021-2024
Royal Victoria Infirmary
1941-1943
The King's College
1941
Background and objectives Membranoproliferative GN C3 glomerulopathy are rare overlapping disorders associated with dysregulation of the alternative complement pathway. Specific etiologic data for pediatric membranoproliferative GN/C3 lacking, outcome based on retrospective studies without data. Design, setting, participants, & measurements A total 80 prevalent patients underwent detailed phenotyping long-term follow-up within National Registry Rare Kidney Diseases (RaDaR). Risk factors...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE MECHANISM OF THE REACTION BETWEEN ETHYLENE AND SULFUR CHLORIDE.1J. B. Conant, E. Hartshorn, and G. O. RichardsonCite this: J. Am. Chem. Soc. 1920, 42, 3, 585–595Publication Date (Print):March 1, 1920Publication History Published online1 May 2002Published inissue 1 March 1920https://pubs.acs.org/doi/10.1021/ja01448a021https://doi.org/10.1021/ja01448a021research-articleACS PublicationsRequest reuse permissionsArticle...
Abstract Background Combined expression of the autophagy-regulatory protein AMBRA1 (activating molecule in Beclin1-regulated autophagy) and terminal differentiation marker loricrin peritumoral epidermis stage I melanomas can identify tumour subsets at low risk metastasis. Objectives To validate combined (AMBLor) as a prognostic biomarker able to both II recurrence. Methods Automated immunohistochemistry was used analyse geographically distinct discovery (n = 540) validation 300) cohorts...
Abstract Chronic non‐healing cutaneous wounds represent a major burden to patients and healthcare providers worldwide, emphasising the continued unmet need for credible efficacious therapeutic approaches wound healing. We have recently shown potential collagen peptides promote proliferation migration during In present study, we demonstrate that application of porcine‐derived significantly increases keratinocyte dermal fibroblast expression integrin α2β1 activation an extracellular...
Abstract The epidermal expression of AMBRA1 and loricrin overlying primary melanomas has recently been validated as a prognostic biomarker able to identify genuinely low risk nonulcerated American Joint Committee on Cancer stage I/II tumours. We have previously shown that the loss these biomarkers is due secretion transforming growth factor-β2 by underlying tumour cells, hypothesize this mechanism used at metastasis facilitate premalignant dissemination. aim present study was evaluate...
staff and a very different atmosphere from the acute wards.My own experience of geriatric long-stay wards, some with high proportion demented patients, is that eventually trained are found who derive much satisfaction their work.They have to learn organize them more like homes not compete wards.The geriatrician does spend time in units, but he must set pattern control admission.This difference view minor matter, however, compared our general agreement on development medical services for...