A5046907164- Malaria Research and Control
- Mosquito-borne diseases and control
- COVID-19 epidemiological studies
- Data-Driven Disease Surveillance
- Vibrio bacteria research studies
- Viral Infections and Vectors
- Travel-related health issues
- Trigeminal Neuralgia and Treatments
- Healthcare Systems and Practices
- SARS-CoV-2 and COVID-19 Research
- Global Maternal and Child Health
- Bacterial Identification and Susceptibility Testing
- Congenital Heart Disease Studies
- COVID-19 Clinical Research Studies
- Viral Infections and Outbreaks Research
- Parasites and Host Interactions
- Statistical Methods and Bayesian Inference
- Tuberculosis Research and Epidemiology
- Vector-borne infectious diseases
- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- Climate Change and Health Impacts
- Health Systems, Economic Evaluations, Quality of Life
- Neurosurgical Procedures and Complications
- Zoonotic diseases and public health
Institut de Recherche pour le Développement
2016-2025
Economic & Social Sciences, Health Systems & Medical Informatics
2016-2025
Inserm
2016-2025
Aix-Marseille Université
2016-2025
Centre d'Etudes Prospectives et d'Informations Internationales
2025
Hôpital de la Timone
2015-2024
Université des Sciences, des Techniques et des Technologies de Bamako
2020-2024
Centre Hospitalier Universitaire de Nice
2009-2024
Institut Pasteur de Bangui
2024
Institut Pasteur
2024
Effective response to infectious disease epidemics requires focused control measures in areas predicted be at high risk of new outbreaks. We aimed test whether mobile operator data could predict the early spatial evolution 2010 Haiti cholera epidemic. Daily case were analysed for 78 study from October 16 December 16, 2010. Movements 2.9 million anonymous phone SIM cards used create a national mobility network. Two gravity models population implemented comparison. Both optimized based on...
Because inadvertent damage of parathyroid glands can lead to postoperative hypocalcemia, their identification and preservation, which be challenging, are pivotal during total thyroidectomy.To determine if intraoperative imaging systems using near-infrared autofluorescence (NIRAF) light identify could improve preservation reduce hypocalcemia.This randomized clinical trial was conducted from September 2016 October 2018, with a 6-month follow-up at 3 referral hospitals in France. Adult patients...
BackgroundPotentially untreatable Plasmodium falciparum malaria threatens the Greater Mekong subregion. A previous series of pilot projects in Myanmar, Laos, Cambodia, and Vietnam suggested that mass drug administration was safe, when added to provision early diagnosis treatment, could reduce reservoir P interrupts transmission. We examined effects a scaled-up programme this strategy four townships eastern Myanmar on incidence malaria.MethodsThe implemented Myawaddy, Kawkareik, Hlaingbwe,...
The objective of this study was to better understand the factors associated with heterogeneity in-hospital COVID-19 morbidity and mortality across France, one countries most affected by in early months pandemic.This geo-epidemiological analysis based on data publicly available government administration websites for 96 administrative departments metropolitan France between March 19 May 11, 2020, including Public Health Regional Agencies, French national statistics institute, Ministry Health....
Background Chikungunya virus (CHIKV) is responsible for acute febrile polyarthralgia and, in a proportion of cases, severe complications including chronic arthritis. CHIKV has spread recently East Africa, South-West Indian Ocean, South-Asia and autochthonous cases have been reported Europe. Although almost all patients are outpatients, medical investigations mainly focused on hospitalised patients. Methodology/Principal Findings Here, we detail clinico-biological characteristics (CHIK)...
Gamma Knife surgery (GKS) is one of the surgical alternatives for treatment drug-resistant trigeminal neuralgia (TN). This study aims to evaluate safety and efficacy GKS in a large population patients with TN very long-term clinical follow-up.Between July 1992 November 2010, 737 presenting were treated using GKS. Data collected prospectively further retrospectively evaluated at Timone University Hospital. The frequency severity pain, as well nerve function, before regularly thereafter....
Spatial and temporal heterogeneities in the risk of malaria have led WHO to recommend fine-scale stratification epidemiological situation, making it possible set up actions clinical or basic researches targeting high-risk zones. Before initiating such studies is necessary define local patterns transmission infection (in time space) order facilitate selection appropriate study population intervention allocation. The aim this was identify, spatially temporally, zones malaria, at household...
Abstract Hepatic periportal fibrosis, which affects 5–10% of subjects infected by Schistosoma mansoni, is caused the T cell-dependent granuloma that develop around schistosome eggs. Experimental models infection have shown and fibrosis are tightly regulated cytokines. However, it unknown why advanced occurs only in certain subjects. The goal present study was to evaluate cytokine response S. mansoni-infected with liver disease an attempt relate susceptibility abnormal production cytokines...
The risk of Plasmodium falciparum infection is variable over space and time this variability related to environmental variability. Environmental factors affect the biological cycle both vector parasite. Despite strong relationship, effects have rarely been included in malaria transmission models. Remote sensing data on environment were incorporated into a temporal model transmission, forecast evolution epidemiology, locality Sudanese savannah area. A dynamic cohort was constituted June 1996...
Abstract We analyzed prospective data on 17,228 European patients who sought treatment at GeoSentinel sites from 1997 to 2007. Gastrointestinal illness (particularly in tourists), fever (those visiting friends and relatives [VFRs]), skin disorders (in tourists) were the most common reasons for seeking medical care. Diagnoses varied by country of origin, region visited, or categories travelers. VFRs returned sub-Saharan Africa Indian Ocean islands more likely experience falciparum malaria...
Background Pituitary stalk interruption syndrome (PSIS) is a particular entity in the population of patients with hypopituitarism. Only rare cases have known genetic cause. Objectives i) To compare subgroups or without extra-pituitary malformations (EPM) cohort PSIS to identify predictive factors evolution, ii) determine incidence mutations pituitary transcription factor genes PSIS. Study design We analyzed features 83 from 80 pedigrees and screened HESX1 , LHX4, OTX2 SOX3 genes. Results had...
Abstract During 1982–2007, alveolar echinococcosis (AE) was diagnosed in 407 patients France, a country previously known to register half of all European patients. To better define high-risk groups we conducted national registry-based study identify areas where persons were at risk and spatial clusters cases. We interviewed 180 AE about their way life compared responses those 517 controls. found that almost lived 22 départements eastern central France (relative 78.63, 95% CI 52.84–117.02)....
Older individuals represent a substantial proportion of international travelers. Because physiological changes and the increased probability underlying medical conditions, older travelers might be at higher risk for least some travel‐associated diseases. With aim describing epidemiology diseases in adults, data were prospectively collected on ill presenting to GeoSentinel sites from 1997 2009. Seven thousand thirty‐four patients aged 60 years over identified as compared 56,042 18–45 years,...
Background In October 2010, cholera importation in Haiti triggered an epidemic that rapidly proved to be the world's largest of seventh pandemic. To establish effective control and elimination policies, strategies rely on analysis dynamics. this report, we describe spatio-temporal dynamics associated environmental factors. Methodology/Principal findings Cholera-associated morbidity mortality data were prospectively collected at commune level according World Health Organization standard...
Urinary tract infections (UTIs) are one of the leading reasons for antibiotic prescriptions in emergency departments (EDs), with half these antibiotics being inappropriately prescribed. Our objective was to assess impact a computerized decision support system (CDSS) on compliance guidelines empirical (antibiotic and duration) UTIs EDs.A multicentre prospective before-and-after controlled interventional study conducted from 19 March 28 October 2012. All adults diagnosed community-acquired...
With limited resources and spatio-temporal heterogeneity of malaria in developing countries, it is still difficult to assess the real impact socioeconomic environmental factors order set up targeted campaigns against at an accurate scale. Our goal was detect hotspots rural area extent which household status meteorological recordings may explain occurrence evolution these hotspots.
Background: Radiosurgery is one of the neurosurgical alternatives for intractable trigeminal neuralgia (TN). Objective: Although acceptable short-/mid-term outcomes have been reported, long-term results not well documented. Methods: We report in 130 patients who underwent radiosurgery classical TN and were subsequently monitored through at least 7 years (median = 9.9, range 7-14.5) follow-up. Results: The median age was 66.5 years. A total 122 (93.8%) became pain free delay 15 days) after...
Dermatophytosis, and particularly the subtype tinea capitis, is common among African children; however, risk factors associated with this condition are poorly understood. To describe epidemiology of dermatophytosis in distinct eco-climatic zones, three cross-sectional surveys were conducted public primary schools located Sahelian, Sudanian Sudano-Guinean zones Mali.Among 590 children (average age 9.7 years) overall clinical prevalence capitis was 39.3%. Tinea 59.5% zone, 41.6% zone 17%...
Given the scarcity of resources in developing countries, malaria treatment requires new strategies that target specific populations, time periods and geographical areas. While spatial pattern transmission is known to vary depending on local conditions, its temporal evolution has yet be evaluated. The aim this study was determine spatio-temporal dynamic central region Burkina Faso, taking into account meteorological factors. Drawing national databases, 101 health areas were studied from 2011...
Trigeminal neuralgia (TN) related to multiple sclerosis (MS) is more difficult manage pharmacologically and surgically.This article aims evaluate the safety efficacy of Gamma Knife surgery (GKS) in this special group patients.Between July 1992 November 2010, 43 cases with than 1 year follow-up were operated GKS for TN MS prospectively evaluated Timone University Hospital, Marseille, France. Radiosurgery using (model B or C Perfexion) was performed. A single 4-mm isocenter positioned at a...