Xian Zhang

ORCID: 0000-0001-9020-0097
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Research Areas
  • Mycotoxins in Agriculture and Food
  • Plant Physiology and Cultivation Studies
  • Plant Reproductive Biology
  • Phytochemistry and Biological Activities
  • Plant Parasitism and Resistance
  • Plant-Microbe Interactions and Immunity
  • Traditional Chinese Medicine Analysis
  • Fungal Biology and Applications
  • Enhanced Oil Recovery Techniques
  • Plant Ecology and Taxonomy Studies
  • Potato Plant Research
  • Pesticide Residue Analysis and Safety
  • Analytical Methods in Pharmaceuticals
  • Plant Pathogens and Resistance
  • Food Quality and Safety Studies
  • Petroleum Processing and Analysis
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Nuts composition and effects
  • GABA and Rice Research
  • Circadian rhythm and melatonin
  • Botany, Ecology, and Taxonomy Studies
  • Genetically Modified Organisms Research
  • Light effects on plants
  • Enterobacteriaceae and Cronobacter Research
  • Plant responses to elevated CO2

Shanxi Agricultural University
2024

China Pharmaceutical University
2014-2022

Ningbo Medical Center Lihuili Hospital
2019

Zhejiang University
2015-2018

Northwest A&F University
2015

Qingdao University
2014

Qingdao Municipal Hospital
2014

Hangzhou Normal University
2013

Hsin Sheng College of Medical Care and Management
1999

Abstract Melatonin is involved in defending against oxidative stress caused by various environmental stresses plants. In this study, the roles of exogenous melatonin regulating local and systemic defense photooxidative cucumber ( Cucumis sativus ) involvement redox signaling were examined. Foliar or rhizospheric treatment with enhanced tolerance to both melatonin‐treated leaves untreated leaves. Increased levels are capable increasing glutathione (reduced [ GSH ]) status. Application H 2 O...

10.1111/jpi.12304 article EN Journal of Pineal Research 2015-12-18

A novel enzyme-linked immunosorbent assay based on magnetic nanoparticles and biotin/streptavidin-HRP (MNP-bsELISA) was developed for rapid sensitive detection of zearalenone (ZEN). The signal enhanced the sensitivity improved by combined use antibody-conjugated biotin-streptavidin system. Under optimized conditions, regression equation quantification ZEN y = −0.4287x + 0.3132 (R2 0.9904). working range 0.07–2.41 ng/mL. limit 0.04 ng/mL IC50 0.37 recovery rates intra-assay inter-assay ranged...

10.3390/toxins7104216 article EN cc-by Toxins 2015-10-20

We developed and tested a prototype of an antibody microarray immunoassay for simultaneous quantitative detection four typical mycotoxins (aflatoxin B1, ochratoxin A, zearalenone, fumonisin B1) in corn samples. The test kit consisted nitrocellulose membrane layered with immobilized monoclonal antibodies against mycotoxins. During the assay, mycotoxin-protein conjugates were biotinylated. signal was enhanced by combination biotin-streptavidin system chemiluminescence (ECL). This improved...

10.3390/toxins10100415 article EN cc-by Toxins 2018-10-15

A rapid and sensitive electrochemical biosensor based on magnetic nanoparticles screen-printed electrodes (MNPs-SPEs sensor) was developed for the detection of ochratoxin (OTA) in cereal feed samples. Different types nanoparticles-based ELISA (MNPs-ELISA) were optimized, signal detection, as well sensitivity, enhanced by combined use (SPEs). Under optimized conditions, calibration curve MNPs-SPEs sensor y = 0.3372x + 0.8324 (R2 0.9805). The linear range limit 0.01–0.82 ng/mL 0.007 ng/mL,...

10.3390/toxins10080317 article EN cc-by Toxins 2018-08-06

Diabetic retinopathy, an inflammatory condition, is one of the devastating complication associated with diabetes that can lead to irreversible blindness. Gentiopicroside (GP), a secoiridoid glycoside, exhibits anti-inflammatory and antioxidant activity. The investigation was carried out explore whether GP could attenuate diabetic retinopathy in rats. Diabetes induced by injecting streptozotocin (STZ) (65 mg/kg) intraperitoneally 8-weeks-old male rats (200–240 g). treatment group received...

10.1177/2058739219847837 article EN cc-by-nc European Journal of Inflammation 2019-01-01

Biowaiver based on the biopharmaceutics classification system (BCS) has been widely used in global market for approval of new generic drug products to avoid unnecessary vivo bioequivalence (BE) studies. However, it is reported that three out four formulations dexketoprofen trometamol (DEX) tablets (BCS class I drug) failed first BE study. The aim this study was determine whether current biowaiver standard reasonable DEX. Thus, we successfully established a physiologically pharmacokinetic...

10.3389/fphar.2022.808456 article EN cc-by Frontiers in Pharmacology 2022-02-10

Seed germination is a fundamental process in plant reproduction, and it involves series of complex physiological mechanisms. The rate

10.3390/ijms252212342 article EN International Journal of Molecular Sciences 2024-11-17

The tomato extreme resistance R-gene encodes Tm2/Tm22 protein that interacts with the tobamovirus movement (MP) to induce hypersensitive response (HR) resulting in local resistance. mediated requires a functional RbCS MP, restricting virus infection. RbCS-MP interaction is also required for systemic “Loss-of-function” allows but not Thus, RbCS, cellular gene, acts as double surveillance agent protect plant from pathogenic attack, suggesting previously un-recognized defense strategy plants.

10.4161/psb.26817 article EN Plant Signaling & Behavior 2013-10-01
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