A5038397278- Catalytic C–H Functionalization Methods
- Synthesis and Catalytic Reactions
- Cyclopropane Reaction Mechanisms
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Catalytic Cross-Coupling Reactions
- Asymmetric Hydrogenation and Catalysis
- Catalytic Alkyne Reactions
- Catalytic Processes in Materials Science
- Graphene research and applications
- Advanced Optical Network Technologies
- Sulfur-Based Synthesis Techniques
- Image and Signal Denoising Methods
- Chemical Reaction Mechanisms
- Advanced Image Processing Techniques
- Optical Network Technologies
- Electrocatalysts for Energy Conversion
- TiO2 Photocatalysis and Solar Cells
- Traffic and Road Safety
- Metal complexes synthesis and properties
- Per- and polyfluoroalkyl substances research
- Fluorine in Organic Chemistry
- Traffic Prediction and Management Techniques
- Atmospheric chemistry and aerosols
- Network Traffic and Congestion Control
Zhejiang Normal University
2003-2025
State Key Laboratory of Respiratory Disease
2019-2024
Guangzhou Medical University
2019-2024
Ministry of Public Security of the People's Republic of China
2014-2023
Traffic Management Research Institute
2014-2023
Sun Yat-sen University
2009-2022
Huawei Technologies (China)
2008-2022
China University of Petroleum, Beijing
2020-2021
Zhejiang Shuren University
2012-2019
Peking University First Hospital
2017
Different morphologies of anatase TiO2 from nanoparticles, nanofibers, and hierarchical spheres to ellipsoid are successfully fabricated via solvothermal reactions titanium n-butoxide acetic acid. The variations morphology, size crystal phase micro-/nanostructures investigated in detail by XRD, FTIR, SEM TEM. Effects different on the photovoltaic performance dye-sensitized solar cells (DSSCs) also discussed based I–V, IPCE, IMPS, IMVS UV-vis absorption diffuse spectra. DSSC sphere...
The mechanism of the Ni-dcype-catalyzed C-H/C-O coupling benzoxazole and naphthalen-2-yl pivalate was studied. Special attention devoted to base effect in C-O oxidative addition C-H activation steps as well substrate step. No C(aryl)-O Ni-dcype found, but nature plays a crucial role following activation. In absence base, azole initiated by product Ni(dcype)(Naph)(PivO), 1B, proceeds via ΔG = 34.7 kcal/mol barrier. Addition Cs2CO3 reaction mixture forms Ni(dcype)(Naph)[PivOCs·CsCO3],...
Theoretical investigations predict that Ni-doped graphene is a promising catalyst for CO oxidation at mild temperatures.
Cyclopropane rings are a prominent structural motif in biologically active molecules. Enantio- and diastereoselective construction of cyclopropanes through C-H activation arenes coupling with readily available cyclopropenes is highly appealing but remains challenge. A dual directing-group-assisted strategy was used to realize mild redox-neutral RhIII -catalyzed cyclopropylation N-phenoxylsulfonamides enantioselective, diastereoselective, regioselective fashion cyclopropenyl secondary...
Transition metal-catalyzed C-H bond halogenation is an important alternative to the highly utilized directed-lithiation methods and increases accessibility of synthetically valuable aryl halide compounds. However, this approach often requires impractical reagents, such as IOAc, or strong co-oxidants. Therefore, development methodology utilizing inexpensive oxidants catalyst containing earth-abundant transition metals under mild experimental conditions would represent a significant advance in...
Epithelial-mesenchymal transition (EMT) plays an important role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Krüpple-like-factor 4 (KLF4), has been suggested to play phenotype transition. However, its function and EMT human alveolar epithelial cells (AECs) remains unclear. This study aimed examine KLF4 EMT. Decreased expression was first observed IPF lung tissues models bleomycin-induced fibrosis. Transgenic mice with overexpression were subjected model showed attenuated...
Cp*Rh(III)-catalyzed [4 + 3] annulation of N-methoxy amides for the direct assembly seven-numbered 2H-azepin-2-one frameworks has been realized with gem-difluorocyclopropenes acting as innovative β-monofluorinated three sp2 carbon sources. Either annular arylamides or linear acrylamides embedment various functional groups, including DNA-tagged substrates, were found to be compatible established reaction mode. A redox-neutral Rh(III)–Rh(V)–Rh(III) catalytic cycle, specifically via...
Considering the importance of chiral allylic amine structural motif and rarity synthetic methods toward their construction, herein, we report a CpXRh(III)-catalyzed enantioselective intermolecular carboamination 1,3-dienes via N-phenoxy amides-derived aryl C–H activation intramolecular amide transfer. The methodology enables direct synthesis variety amines with embedment phenol functionalities proceeds under mild conditions sequential formation completely regioselective C–C bond highly C–N...
Anchor selection or learning has become a critical component in large-scale multi-view clustering. Existing anchor-based methods, which either select-then-fix initialize-then-optimize with orthogonality, yield promising performance. However, these methods still suffer from instability of initialization insufficient depiction data distribution. Moreover, the desired properties anchors clustering remain unspecified. To address issues, this paper first formalizes characteristics anchors, namely...
Density functional theory (DFT) calculations were used to study the mechanism for cleavage reaction of RNA analogue HpPNP (HpPNP = 2-hydroxypropyl-4-nitrophenyl phosphate) catalyzed by dinuclear Zn(II) complex 1,3-bis(1,4,7-triazacyclonon-1-yl)-2-hydroxypropane (Zn2(L2O)). We present a binding mode in which each terminal phosphoryl oxygen atom binds one zinc center, respectively, and nucleophilic 2-hydroxypropyl group coordinates ions, while hydroxide from deprotonation water molecule other...
The reaction mechanisms and chemoselectivity on the intramolecular allylic C–H amination versus alkene aziridination of 4-pentenylsulfamate promoted by four elaborately selected dirhodium paddlewheel complexes are investigated a DFT approach. A predominant singlet concerted, highly asynchronous pathway an alternative triplet stepwise obtained in either or reactions when mediated weak electron-donating catalysts. is under strongly donating rate-determining step H-abstraction process....
The mechanisms and enantioselectivities of the dirhodium (Rh2L4, L = formate, N-methylformamide, S-nap)-catalyzed intramolecular C–H aminations 3-phenylpropylsulfamate ester have been investigated in detail with BPW91 density functional theory computations. reactions catalyzed by Rh2II,II catalysts start from oxidation dimer to a triplet mixed-valent Rh2II,III–nitrene radical, which should facilitate radical H-atom abstraction. However, Rh2(formate)4-promoted reaction, as result...
By making use of a direct C–H activation strategy, an efficient osmium(II)-catalyzed redox-neutral [4 + 2] annulation N-methoxybenzamides with alkynes has been accomplished. Computational and experimental studies revealed that such transformation leading to the synthesis isoquinolone core might follow Os(II)–Os(IV)–Os(II) catalytic pathway, in which unusual HOAc-assisted oxidative addition osmium(II) into N–O bond generate osmium(IV) species was involved as one key transition states. Further...
A robust and convenient rhodium-catalyzed unconventionally regioselective C–H activation/[4 + 2] annulation for the synthesis of isoquinolones which are prevalent in natural products pharmaceuticals was developed.
Abstract Herein, multiple types of chiral Os(II) complexes have been designed to address the appealing yet challenging asymmetric C(sp 3 )−H functionalization, among which Os(II)/Salox species is found be most efficient for precise stereocontrol in realizing amidation. As exemplified by enantioenriched pyrrolidinone synthesis, such tailored catalyst efficiently enables an intramolecular site‐/enantioselective amidation γ‐position dioxazolone substrates, benzyl, propargyl and allyl groups...