A5041156552- Obesity, Physical Activity, Diet
- Nutrition, Genetics, and Disease
- Health and Lifestyle Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Diet and metabolism studies
- Lipid metabolism and biosynthesis
- Vitamin C and Antioxidants Research
- Nutrition and Health in Aging
- Nutritional Studies and Diet
- Mobile Health and mHealth Applications
- Adipose Tissue and Metabolism
- Genetics and Physical Performance
- Circadian rhythm and melatonin
- Gut microbiota and health
- Muscle metabolism and nutrition
- Menstrual Health and Disorders
- Celiac Disease Research and Management
- Fatty Acid Research and Health
- Sports Performance and Training
- Consumer Attitudes and Food Labeling
- Regulation of Appetite and Obesity
- Metabolism, Diabetes, and Cancer
- Biochemical Analysis and Sensing Techniques
- Tea Polyphenols and Effects
- Nerve injury and regeneration
Universidad Autónoma de Madrid
2017-2025
IMDEA Food
2017-2025
Universidad Europea
2023-2025
Madrid Institute for Advanced Studies
2017-2024
We describe here for the first time consistent observation of two metabotypes associated with resveratrol metabolism by human gut microbiota, that is, lunularin (LUNU)-producers and LUNU non-producers. In healthy volunteers (n = 195), was reduced to dihydroresveratrol, which only in LUNU-producer metabotype sequentially dehydroxylated at 5-position yield 3-position produce 4-hydroxydibenzyl. These metabolites (also 3,4'-dihydroxy-trans-stilbene some LUNU-producers) were detected urine (or)...
The increasing prevalence of diet-related diseases calls for an improvement in nutritional advice. Personalized nutrition aims to solve this problem by adapting dietary and lifestyle guidelines the unique circumstances each individual. With latest advances technology data science, researchers can now automatically collect analyze large amounts from a variety sources, including wearable smart devices. By combining these diverse data, more comprehensive insights human body its be achieved....
Abstract The increased prevalence of childhood obesity is expected to translate in the near future into a concomitant soaring multiple cardio-metabolic diseases. Obesity has complex, multifactorial etiology, that includes and multidomain potential risk factors: genetics, dietary physical activity habits, socio-economic environment, lifestyle, etc. In addition, all these factors are exert their influence through specific especially convoluted way during childhood, given fast growth along this...
Objectives: Innovative precision dietary procedures are required to promote healthy aging.This study aimed evaluate the effects of a personalised strategy based on inclusion individualised foods and digital tools overall health status quality life within follow-up 3 months in older adults with overweight or obesity.Methods: 127 men women aged between 50 80 years overweight/obesity participated studybetween January 2020 September at Center for Nutrition Research-University Navarra...
(1) Background: Childhood rapid weight gain during development has been postulated as a predictor of obesity. The objective this study was to investigate the effect single nucleotide polymorphisms (SNPs) on annual and height growth, well identifying possible lifestyle factors involved. (2) Methods: As part GENYAL study, 221 children (6–8 years old) Madrid (Spain) were enrolled. A total 11 SNPs associated with high childhood body mass indexes (BMIs) assessed. Anthropometric measurements,...
The aim of this study was to evaluate the distribution energy intake and macronutrients consumption throughout day, how its effect on nutritional status can be modulated by presence rs3749474 polymorphism CLOCK gene in Cantoblanco Platform for Nutritional Genomics (“GENYAL Platform”). This cross-sectional carried out 898 volunteers between 18 69 years old (65.5% women). Anthropometric measurements, social issues health, dietary, biochemical, genetic, physical activity data were collected....
Childhood obesity is a growing concern, because the problem affects high percentage of children and source many diseases in present future, which can lead to decrease life expectancy quality life. In order combat problem, it necessary analyze factors associated with excess weight childhood act on them try curb trend observed recent years. Various socio-demographic aspects, as well inactivity sedentary lifestyle are that an increased risk central adiposity. With great prominence this issue,...
Excess weight (EW) in children has become a severe public health problem. The present study aimed to describe the main lifestyle characteristics and their possible association with nutritional status group of schoolchildren enrolled GENYAL study, where 221 first or second grade primary education (6-9 years old) were included. Anthropometric (BMI bioimpedance), dietary intake (twice-repeated 24 h food record), physical activity questionnaire) data collected. Logistic linear regressions,...
Abstract Background Overweight and obesity are defined by an anomalous or excessive fat accumulation that may compromise health. To find single-nucleotide polymorphisms (SNPs) influencing metabolic phenotypes associated with the state, we analyze multiple anthropometric clinical parameters in a cohort of 790 healthy volunteers study potential associations 48 manually curated SNPs, genes functionally mechanistic target rapamycin (mTOR) pathway. Results We identify validate rs2291007 within...
Sport performance is influenced by several factors, including genetic susceptibility. In the past years, specific single nucleotide polymorphisms have been associated to sport performance; however, these effects should be considered in multivariable prediction systems since they are related a polygenic inheritance. The aim of this study was design endurance score (GES) and analyze its association with anthropometric, nutritional efficiency variables cross-sectional within fifteen male...
Objective This article describes the methodology and summarizes some preliminary results of GENYAL study aiming to design validate a predictive model, considering both environmental genetic factors, that identifies children who would benefit most from actions aimed at reducing risk obesity its complications. Design The is cluster randomized clinical trial with 5-year follow-up. initial evaluation was carried out in 2017. schools were randomly split into intervention (nutritional education)...
Complex interactions between innate and adaptive immune effectors are an important component in the induction of obesity. Particularly, different subsets myeloid cells play key roles metabolic liver diseases and, therefore, promising targets for intervention strategies. Chenopodium quinoa seeds constitute a good source immunonutritional compounds, which help prevent high-fat, diet-enhanced signaling via TLR4/MyD88 that boosts inflammation. Herein, two mouse models—wild type (WT) tributyltin...
ABSTRACT Non-responsive celiac disease (NRCD) poses a challenge for clinicians due to the persistence of symptoms despite maintaining gluten-free diet (GFD). This study investigated gut microbiome, mucosal integrity, and metabolomic profiles 39 NRCD patients gain insights into underlying mechanisms contributing symptom persistence. Two distinct clusters were identified based on clinical demographic variables not influenced by gluten consumption. Cluster 1, labelled “Low-grade symptoms,”...