A5046605158- Ichthyology and Marine Biology
- Fish Biology and Ecology Studies
- Fish biology, ecology, and behavior
- Fish Ecology and Management Studies
- Asymmetric Hydrogenation and Catalysis
- Paleontology and Evolutionary Biology
- Marine animal studies overview
- Synthesis of β-Lactam Compounds
- Analytical Chemistry and Chromatography
- Developmental Biology and Gene Regulation
- Genomics and Phylogenetic Studies
- Erythrocyte Function and Pathophysiology
- Synthesis and Catalytic Reactions
- CRISPR and Genetic Engineering
- Robotic Locomotion and Control
- Reproductive Biology and Fertility
- Chromosomal and Genetic Variations
- Aquaculture Nutrition and Growth
- Enzyme Catalysis and Immobilization
- X-ray Diffraction in Crystallography
- Animal Genetics and Reproduction
- Surface Chemistry and Catalysis
- Connective tissue disorders research
- Protease and Inhibitor Mechanisms
- Skin and Cellular Biology Research
Jikei University School of Medicine
2010-2024
Mitsubishi Chemical (Japan)
2018
Mitsubishi Tanabe Pharma Corporation
2018
Keio University
2013-2017
Experimental Station
2015
Virginia Mason Medical Center
2004-2012
Benaroya Research Institute
2004-2012
Mitsubishi Group (Japan)
2010
Harvard University
2006
University of Washington
2006
The discovery of a living coelacanth specimen in 1938 was remarkable, as this lineage lobe-finned fish thought to have become extinct 70 million years ago. modern looks remarkably similar many its ancient relatives, and evolutionary proximity our own ancestors provides glimpse the that first walked on land. Here we report genome sequence African coelacanth, Latimeria chalumnae. Through phylogenomic analysis, conclude lungfish, not is closest relative tetrapods. Coelacanth protein-coding...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAsymmetric Hydrogenation of Olefins with Aprotic Oxygen Functionalities Catalyzed by BINAP-Ru(II) ComplexesTetsuo Ohta, Tsutomu Miyake, Nobuo Seido, Hidenori Kumobayashi, and Hidemasa TakayaCite this: J. Org. Chem. 1995, 60, 2, 357–363Publication Date (Print):January 1, 1995Publication History Published online1 May 2002Published inissue 1 January 1995https://doi.org/10.1021/jo00107a014Request reuse permissionsArticle...
The developmental stages of Oreochromis niloticus are similar to those described in other mouth-breeding tilapias except that, as zebrafish, no cavity was found the blastula. Variation rate development embryo and larva O. within a clutch eggs well between clutches. Hatching glands for first time tilapias. They widely distributed ectoderm covering head, body, tail, surface yolk sac near its attachment embryo. Timing larval is that mouthbrooding tilapias, but slower than substrate-spawning A...
Rabbit morulae were exposed to a vitrification solution-modified PBS [PB1] medium containing 40% ethylene glycol + 18% Ficoll 0.3 M sucrose (EFS) for 2, 5, or 10 min at 20 ° C and vitrified in liquid nitrogen. When rapidly warmed, 96% had an intact zona pellucida. embryos cultured after removal of the mucin coat, high proportions them formed blastocoel (79−100%), but percentage developed fully expanded blastocysts decreased with increased exposure time 87%, 40%, 17%). The survival rate coat...
The living coelacanth is a lobe-finned fish that represents an early evolutionary departure from the lineage led to land vertebrates, and of extreme interest scientifically. It has changed very little in appearance fossilized coelacanths Cretaceous (150 65 million years ago), often referred as "living fossil." An important general question whether long-term stasis morphological evolution associated with genome evolution. To this end we have used targeted sequencing for acquiring 1,612,752 bp...
Cranial development in larval Atlantic cod Gadus morhua was studied throughout ontogeny using specimens treated by staining and clearing, scanning electron microscopy histology. Newly hatched larvae have closed mouths, no operculii, five well-developed branchial arches, transversii ventralis muscles. During the endogenous feeding (yolk-sac) stage, viscerocranial structures remain simple nonarticulated. Six days after hatching at 5°C, articulation occurs between quadrate/Meckel's cartilage...
The calcium-sensing receptor (CaSR) plays an important role in sensing extracellular calcium ions and regulating parathyroid hormone secretion by gland cells, the is a suitable target for treatment of hyperparathyroidism. Cinacalcet hydrochloride representative CaSR agonist which widely used However, it has several issues to clinical use, such as nausea/vomiting strong inhibition CYP2D6. We tried improve these cinacalcet new pharmaceutical agent preferable agonist. Optimization from resulted...
Timing and pattern of expression alkaline phosphatase was examined during early differentiation the 1st arch skeleton in inbred C57BL/6 mice. Embryos were recovered between 10 18 d gestation staged using a detailed staging table craniofacial development prior to histochemical examination. Expression is initiated at stage 20.2 plasma membrane mesenchymal cells distal region first arch. strongest osteoid (unmineralised bone matrix) presumptive periosteum 21.32. Mineralisation begins E23....
Patterning, cellular differentiation, and developmental sequences of dermal denticles (denticles) are described for the skate Leucoraja erinacea. Development proceeds caudo-rostrally in tail trunk. Once three rows form trunk, begin to appear region pelvic girdle, medio-caudal eyes on pectoral fins. Although timing differentiation differs among different locations body, development a denticle is identical all locations. Thickening epidermis as lamina marks initiation development. A single...
The ventral gill arch skeleton was examined in some representatives of batoid fishes. homology the components elucidated by comparing similarities and differences among arches chondrichthyans, attempts were made to justify giving causal mechanisms chondrogenesis associated with skeleton. ceratohyal is present fishes, its functional replacement, pseudohyal, seems incomplete most groups except stingrays. medial fusion pseudohyal successive ceratobranchials occurs varying degrees stingray...
The tuatara (Sphenodon punctatus) is of "extraordinary biological interest" as the most distinctive surviving reptilian lineage (Rhyncocephalia) in world. To provide a genomic resource for an understanding genome evolution reptiles, and part larger project to produce resources various reptiles (http://evogen.jgi.doe.gov/second_levels/BACs/Our_libraries.html), large-insert bacterial artificial chromosome (BAC) library from male was constructed. consists 215 424 individual clones whose average...
Abstract A BAC library was constructed from Astatotilapia burtoni , a haplochromine cichlid that is found in Lake Tanganyika, East Africa, and its surrounding rivers. The generated genomic DNA of blood cells comprises 96,768 individual clones. Its median insert size 150 kb the coverage expected to represent about 14 genome equivalents. evaluation based on estimates were obtained by flow cytometry. In addition, hybridization screens with five probes largely corroborate above estimate,...
Journal Article Development and morphology of rostral cartilages in batoid fishes (Chondrichthyes: Batoidea), with comments on homology within vertebrates Get access TSUTOMU MIYAKE, MIYAKE 1Department Biology, Dalhousie University, Halifax, Nova Scotia B3H 4J1, Canada Search for other works by this author on: Oxford Academic Google Scholar JOHN D. McEACHRAN, McEACHRAN *Department Wildlife Fisheries Sciences, Texas A&M College Station, 77843, U.S.A PETER J. WALTON, WALTON †Baylor Medicine, 1...