A5020921749- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Management of metastatic bone disease
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Cervical and Thoracic Myelopathy
- Knee injuries and reconstruction techniques
- Musculoskeletal pain and rehabilitation
- Medical Imaging and Analysis
- Sarcoma Diagnosis and Treatment
- Osteoarthritis Treatment and Mechanisms
- Pelvic and Acetabular Injuries
- Orthopedic Infections and Treatments
- Bone Tumor Diagnosis and Treatments
- Cancer Diagnosis and Treatment
- Mesenchymal stem cell research
- Medical Imaging Techniques and Applications
- Bone fractures and treatments
- Lower Extremity Biomechanics and Pathologies
- Bone health and osteoporosis research
- Spinal Hematomas and Complications
- Shoulder Injury and Treatment
- Tendon Structure and Treatment
- Musculoskeletal synovial abnormalities and treatments
- Anesthesia and Pain Management
Nihon University
2015-2024
Tachikawa Hospital
2022
Nihon University Itabashi Hospital
1998-2021
Surugadai Nihon University Hospital
2005-2018
Leiden University
2016
University Medical Center Groningen
2016
University Medical Center Utrecht
2016
University College London
2016
Hospital for Special Surgery
2013
Jichi Medical University
2011
A semi-prospective clinical study was conducted.To evaluate the accuracy of a revised scoring system predicting metastatic spinal tumor prognosis and suitability subsequent treatment strategy.We used for preoperative evaluation tumors selected methods predicted prognosis. In previous version our system, reliability 63.3% in 128 patients with tumors.The participants were 164 who died after surgery 82 conservative treatment. Six parameters system. Each parameter ranged from 0 to 5 points,...
An assessment system for the prognosis of metastatic spine tumors was evaluated 64 cases who had undergone surgery. Six parameters were employed in system: 1) general condition, 2) number extraspinal bone metastases, 3) metastases vertebral body, 4) to major internal organs (lungs, liver, kidneys, and brain), 5) primary site cancer, 6) severity spinal cord palsy. Each parameter ranged from 0 2 points. The total score obtained each patient can be correlated with prognosis, while being...
Study Design. The risk factors of patients with and without radiculopathy after laminoplasty the cervical spine were compared retrospectively. Objectives. To study association between variables postlaminoplastic to clarify pathogenesis devise preventive measures. Summary Background Data. Radiculopathy on expanded side has been attributed mainly traumatic surgical techniques, whereas hinged traction, tethering, or kinking nerve root that resulted from posterior shift spinal cord preoperative...
Fifty-seven patients with low back pain and sciatica of various causes were reviewed reference to problems associated pedicle plate fixation the lumbar spine. Eleven percent had neurologic postoperatively 3.5% (two patients) severe sensory impairments. All this complication in early phases study. Of 297 screws, 17 broke, ie, 5.7%. These breakages occurred 12 57 (21%). In spondylolisthesis, degree slip correction averaged 53% postoperatively, which decreased 35% at 1-year follow-up. Slip...
Prospective study.To evaluate our treatment outcome for spinal metastases using strategy based on prognostic scoring system.In the of metastases, life expectancy is most important, and system metastatic spine tumor prognosis has been useful such evaluation.Conservative or palliative surgery was indicated in patients with a predicted less than 6 months those multiple vertebral whereas excisional performed predicated 1 year more, metastasis single vertebra. One hundred eighty-three were...
Surgery for symptomatic spinal metastases aims to improve quality of life, pain, function, and stability. Complications in the postoperative period are not uncommon; therefore, it is important select appropriate patients who likely benefit greatest from surgery. Previous studies have focused on predicting survival rather than life after surgery.To determine preoperative patient characteristics that predict undergo surgery metastases.In a prospective cohort study 922 with underwent surgery,...
<h3>Importance</h3> The optimal management for acute traumatic cervical spinal cord injury (SCI) is unknown. <h3>Objective</h3> To determine whether early surgical decompression results in better motor recovery than delayed treatment patients with incomplete SCI associated preexisting canal stenosis but without bone injury. <h3>Design, Setting, and Participants</h3> This multicenter randomized clinical trial was conducted 43 tertiary referral centers Japan from December 2011 through November...
The effects of nicotine on intervertebral discs in rabbits were studied experimentally.To investigate the vascular buds for elucidating mechanism nicotine-induced vertebral disc degeneration.Several groups have suggested that cigarette smoking is associated with low back pain, but exact not yet fully understood.The pump was filled a diluted solution, then implanted under skin 8 weeks. This model designed to maintain blood concentration at approximately 110 ng/mL. Rabbits receiving...
In Brief Study Design. Retrospective multi-institutional study Objective. To describe the surgical outcomes in patients with ossification of posterior longitudinal ligament thoracic spine (T-OPLL) and to clarify factors related outcomes. Summary Background Data. Detailed analyses T-OPLL have been difficult because rarity this disease. Methods. The subjects were 154 who surgically treated at 34 institutions between 1998 2002. procedures laminectomy 36, laminoplasty 51, anterior decompression...
In Brief Study Design. A multicenter cohort study was performed retrospectively. Objective. To identify radiographic predictors for the development of myelopathy in patients with ossification posterior longitudinal ligaments (OPLL). Summary Background Data. The pathomechanism OPLL remains unknown. Some large have not exhibited a long periods time. Predicting course future neurologic deterioration asyptomatic is difficult at their initial visit. Methods. total 156 from 16 spine institutes an...
Introduction Metastatic spinal cancer is a common condition that may lead to instability, pain and paralysis. In the 1980s, surgery was discouraged because results showed worse neurological outcomes compared with radiotherapy alone. However, advent of modern imaging stabilisation techniques, role has regained centre stage, though few studies have assessed quality life functional after surgery. Objective We investigated whether provides sustained improvement in relief for patients symptomatic...
Purpose Survival after metastatic cancer has improved at the cost of increased presentation with spinal disease. For patients pathologic fractures and/or cord compression, surgical intervention may relieve pain and improve quality life. Surgery is generally considered to be inappropriate if anticipated survival < 3 months. The aim this international multicenter study was analyze data from who died within months or 2 years surgery, identify preoperative factors associated poor good...
A retrospective clinical review of patients with thoracolumbar junction disc herniation.To evaluate the features herniation and to prepare a chart for level diagnosis in neurologic findings symptoms.Thoracolumbar herniations show variety signs symptoms because complexity upper lower neurons spinal cord, cauda equina, nerve roots. Furthermore, much is still unknown about their rare frequency.The 26 who had undergone operations single at T10-T11 through L2-L3 were investigated. Affected levels...
A retrospective study.To report the clinical course and significance of postoperative radiolucent zones around pedicle screws.Radiolucent screws have been considered to indicate loss fixation, delayed union, or pseudarthrosis. Few reports described them.Plain radiographs were evaluated from 190 patients with screw fixation. When 1 mm greater circumferential lucency was confirmed a on plain 2 more directions, patient judged as clear-zone positive. The positivity investigated relationships...
Retrospective multicenter study.To review the clinical characteristics of traumatic cervical spinal cord injury (SCI) associated with ossification posterior longitudinal ligament (OPLL).Despite its potentially devastating consequences, there is a lack information about acute SCI complicated by OPLL.This study included consecutive patients (Frankel A, B, and C) who were admitted within 48 hours to 34 spine institutions across Japan. For analysis neurologic outcome, had completed at least...
We have previously reported that mature adipocyte-derived dedifferentiated fat (DFAT) cells a high proliferative activity and the potential to differentiate into lineages of mesenchymal tissue similar bone marrow stem (MSCs). In present study, we examined effects autologous DFAT cell transplantation on regeneration in rabbit defect model an ovariectomy (OVX)-induced osteoporosis model. The formation tissue-engineered (TEB) was observed when were loaded onto β-tricalcium phosphate...
While bracing is the standard conservative treatment for acute osteoporotic compression fracture, efficacy of different brace treatments has not been extensively studied. We aimed to clarify and compare preventive effect on deformity vertebral body other clinical results in this patient cohort. This multicenter nationwide prospective randomized study included female patients aged 65⁻85 years with one-level fractures. assigned within four weeks injury either a rigid-brace or soft-brace...
Clinical testing of segmental pedicular screw hook fixation repairing defects in lumbar spondylolysis.The authors tested using ISOLA implants (AcroMed Corp., Cleveland, OH) to maintain direct repair the defect pars interarticularis while fusion occurs. The device should not break takes place with out a postoperative body cast.Previous techniques spondylolysis have been successful universally, and wire breakage has occurred despite use cast.This technique stabilizes bone grafted detect by...