A5089249964- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Cervical and Thoracic Myelopathy
- Intraoperative Neuromonitoring and Anesthetic Effects
- Meningioma and schwannoma management
- Scoliosis diagnosis and treatment
- Musculoskeletal pain and rehabilitation
- Spinal Hematomas and Complications
- Spinal Cord Injury Research
- Spondyloarthritis Studies and Treatments
- Spinal Dysraphism and Malformations
- Heterotopic Ossification and Related Conditions
- Nerve Injury and Rehabilitation
- Pelvic and Acetabular Injuries
- Osteomyelitis and Bone Disorders Research
- Medical Imaging and Analysis
- Neurofibromatosis and Schwannoma Cases
- Bone Tumor Diagnosis and Treatments
- Pain Mechanisms and Treatments
- Bone health and osteoporosis research
- Botulinum Toxin and Related Neurological Disorders
- Bone Tissue Engineering Materials
- Anesthesia and Pain Management
- Pregnancy-related medical research
- Mesenchymal stem cell research
Hirosaki University
2015-2024
Japan Agency for Medical Research and Development
2021-2023
Kitasato University
2023
Research Organization of Information and Systems
2018-2023
Weatherford College
2023
Graduate School USA
2021
Chiba University
2021
Kudanzaka Hospital
2021
Hirosaki University Hospital
2021
Nagoya University
2016-2019
Object Although multimodal intraoperative spinal cord monitoring provides greater accuracy, transcranial electrical stimulation motor evoked potential (TcMEP) became the gold standard for monitoring. However, there is no definite alarm point TcMEPs because a multicenter study lacking. Thus, based on their experience with 48 true-positive cases (that is, decrease in potentials followed by new neurological deficit postoperatively) encountered between 2007 and 2009, authors set 70% amplitude as...
Ossification of the posterior longitudinal ligament (OPLL) can cause severe and irreversible paralysis in not only cervical spine but also thoracolumbar spine. To date, however, prevalence distribution OPLL whole has been precisely evaluated patients with OPLL. Therefore, we conducted a multi-center study to comprehensively evaluate using multi-detector computed tomography (CT) images analyze what factors predict presence ossified lesions who were diagnosed by plain X-ray. Three hundred...
<h3>Importance</h3> The optimal management for acute traumatic cervical spinal cord injury (SCI) is unknown. <h3>Objective</h3> To determine whether early surgical decompression results in better motor recovery than delayed treatment patients with incomplete SCI associated preexisting canal stenosis but without bone injury. <h3>Design, Setting, and Participants</h3> This multicenter randomized clinical trial was conducted 43 tertiary referral centers Japan from December 2011 through November...
Prospective multicenter study.To analyze the incidence of intraoperative spinal neuromonitoring (IONM) alerts and neurological complications, as well to determine which interventions are most effective at preventing postoperative complications following IONM in high risk surgeries.IONM may play a role identifying neural damage; however, few studies have clarified outcomes intervention after alerts.We analyzed 2867 patients who underwent surgery for pathology using transcranial electrical...
Prospective, multicenter, nationwide study.To investigate perioperative complications and risk factors in surgery for thoracic ossification of the posterior longitudinal ligament (T-OPLL) using data from registry Japanese Multicenter Research Organization Ossification Spinal Ligament.There is no prospective multicenter study surgical T-OPLL, previous retrospective studies have lacked details.Surgical methods, preoperative radiographic findings, pre- postoperative myelopathy (Japanese...
A prospective study in 19 patients after cervical laminoplasty, using magnetic resonance imaging.To evaluate the value of spinal cord shift at 24 hours laminoplasty.Postoperative C5 palsy is a noticeable complication within 1 week laminoplasty. The root tethering due to posterior laminoplasty was reported as one causes palsy. However, surgery unknown.The measured consecutive on images and 2 weeks laminoplasty.The mean 2.8 mm, with maximum level, decreasing 1.9 mm weeks. correlated amount...
Radiographic findings may provide clues to the underlying cause of neck symptoms. However, these associations remain controversial. This study investigates association between roentgenographic cervical spine and symptoms in a Japanese community population.A total 762 volunteers participated this study. Sagittal radiographs were taken questionnaire about presence visual analog scale (VAS) for pain or stiff shoulder was completed. The sagittal alignment (C2-C7) degenerative index measured from...
Study Design. Retrospective study comparing postoperative clinical outcomes after cervical laminoplasty between K-line (–) ossification of the posterior longitudinal ligament (OPLL) and (+) OPLL in neck-flexed position. Objective. To investigate using Japanese Orthopedic Association (JOA) scores, grip-and-release (GR) foot-tap (FT) test scores patients with Summary Background Data. Cervical has been reported to lead poor good OPLL. The spine, however, continues moving extension flexion...
Supra/interspinous ligaments connect adjacent spinous processes and act as a stabilizer of the spine. As with other spinal ligaments, it can become ossified. However, few report have discussed ossification supra/interspinous (OSIL), so its epidemiology remains unknown. We therefore aimed to investigate prevalence distribution OSIL in symptomatic patients cervical posterior longitudinal ligament (OPLL). The participants our study were OPLL who diagnosed by standard radiographs whole spine CT...
This was a retrospective multicenter study.To clarify the progression of diffuse idiopathic skeletal hyperostosis (DISH) using whole-spine computed tomography in patients with cervical ossification posterior longitudinal ligament (OPLL).DISH and OPLL frequently coexist, can cause ankylosing spinal fractures due to biomechanical changes fragility affected vertebrae. The epidemiology pathophysiology DISH occurring are unclear.We used determine prevalence 234 diagnosis based on plain...
Study Design A radiographic study in 111 patients using radiographs was conducted. Objective To clarify whether the modified laminoplasty with C3 laminectomy preserving semispinalis cervicis (SSC) inserted into C2 could maintain postopertive range of motion (ROM) and sagittal alignment compared conventional C3-C7 reattaching muscle to C2. Summary Background Data Intraoperative injury SSC is relevant significant loss ROM malalignment after laminoplasty. expose lamina, however, not be...
A clinical and cohort study.The first purpose of this study was to investigate the standard value a simple foot tapping test (FTT) in large healthy population. The second elucidate validity FTT as quantitative assessment lower extremity motor function for cervical compressive myelopathy.Several performance tests have been reported objective assessments severity myelopathy. is simplest easiest method analysis limb dysfunction upper neuron diseases. However, there were few studies about...
Study Design Surgeon survey. Objective To analyze multimodal intraoperative monitoring (MIOM) for different combinations of methods based on the collected data and determine best combination. Methods A questionnaire was sent to 72 training institutions compile about that had been conducted during preceding 5 years obtain following: (1) types monitoring; (2) names number diseases; (3) conditions anesthesia; (4) condition stimulation, monitored muscle its number; (5) complications; (6)...
In patients with ossification of the posterior longitudinal ligament (OPLL) in cervical spine, it is well known that thoracic ossified lesions often coexist and can cause severe myelopathy. However, prevalence OPLL at each level lumbar spinal segments unknown. The aims this study were to investigate how occurs thoracolumbar spine a radiological diagnosis identify levels most likely develop ossification. Data collected from 20 institutions Japan. Three hundred twenty-two included. index (OP...
It has been reported that female rats have a sex-related advantage in functional recovery and neuroprotection after spinal cord injury (SCI). However, the association between anxiety neurological function SCI male remains unclear. The aim of this study was to examine differences dysfunction adult C57/BL6 mice. After laminectomy at 10th thoracic level, contusive induced. sham group received only T10 laminectomy. Behavior testing (anxiety, motor/sensory function) performed for 6 weeks SCI....
Object Previous reports of redundant nerve roots (RNRs) the cauda equina have been limited to evaluations based on myelography. Neither imaging nor clinical features RNRs in relation magnetic resonance (MR) elaborated. The MR characteristics were evaluated using Japanese Orthopaedic Association score before and after surgery. Methods There 44 patients with L4–5 spondylolisthesis which a complete blockage was demonstrated All underwent posterior interbody fusion. Based myelographic findings,...
Objective: We compared screening methods for asymptomatic venous thromboembolism (VTE) in patients with acute spine and spinal cord injuries (SCI). Patients were screened by D-dimer monitoring alone (DS group) or combined ultrasonography (DUS group).Design: Prospective cohort study.Setting: One department of a university hospital Japan.Participants: 114 treated SCI between 2011 2017.Interventions: N/A.Outcome Measures: D-dimers measured upon admission 1, 3, 5, 7, 14 days thereafter....
Prospectively collected, multicenter, nationwide study.The aim of this study was to investigate recent surgical methods and trends, outcomes, perioperative complications in surgery for thoracic ossification the ligamentum flavum (T-OLF).A prospective multicenter risk factors T-OLF has not been performed, previous retrospective studies have lacked details these items.Surgical methods, pre- postoperative myelopathy (Japanese Orthopedic Association [JOA] score), symptoms, intraoperative...
Abstract This prospective multicenter study, established by the Japanese Ministry of Health, Labour and Welfare involving 27 institutions, aimed to compare postoperative outcomes between laminoplasty (LM) posterior fusion (PF) for cervical ossification longitudinal ligament (OPLL), in order address controversy surrounding role instrumented cases surgical decompression OPLL. 478 patients were considered participation study; from among them, 189 (137 52 with LM PF, respectively) included...