A5102874221- Spine and Intervertebral Disc Pathology
- Cervical and Thoracic Myelopathy
- Spinal Fractures and Fixation Techniques
- Musculoskeletal pain and rehabilitation
- Scoliosis diagnosis and treatment
- Spinal Cord Injury Research
- Nerve Injury and Rehabilitation
- Venous Thromboembolism Diagnosis and Management
- Fuel Cells and Related Materials
- Mesenchymal stem cell research
- Spinal Hematomas and Complications
- Sports injuries and prevention
- Medical Imaging and Analysis
- Osteoarthritis Treatment and Mechanisms
- Endometriosis Research and Treatment
- Eosinophilic Disorders and Syndromes
- Heterotopic Ossification and Related Conditions
- 3D IC and TSV technologies
- Adenosine and Purinergic Signaling
- Advanced Numerical Analysis Techniques
- Sarcoidosis and Beryllium Toxicity Research
- Neurosurgical Procedures and Complications
- Pregnancy-related medical research
- Low-power high-performance VLSI design
- Cutaneous Melanoma Detection and Management
Hirosaki University
2008-2024
Level (Czechia)
2021
Weatherford College
2021
Akita Red Cross Hospital
2021
Open Evidence
2021
Towada City Hospital
2016
Tokyo Institute of Technology
2016
Panasonic (Japan)
1997
Kyoto University
1994
Study Design. Retrospective study comparing postoperative clinical outcomes after cervical laminoplasty between K-line (–) ossification of the posterior longitudinal ligament (OPLL) and (+) OPLL in neck-flexed position. Objective. To investigate using Japanese Orthopedic Association (JOA) scores, grip-and-release (GR) foot-tap (FT) test scores patients with Summary Background Data. Cervical has been reported to lead poor good OPLL. The spine, however, continues moving extension flexion...
A clinical and cohort study.The first purpose of this study was to investigate the standard value a simple foot tapping test (FTT) in large healthy population. The second elucidate validity FTT as quantitative assessment lower extremity motor function for cervical compressive myelopathy.Several performance tests have been reported objective assessments severity myelopathy. is simplest easiest method analysis limb dysfunction upper neuron diseases. However, there were few studies about...
It has been reported that female rats have a sex-related advantage in functional recovery and neuroprotection after spinal cord injury (SCI). However, the association between anxiety neurological function SCI male remains unclear. The aim of this study was to examine differences dysfunction adult C57/BL6 mice. After laminectomy at 10th thoracic level, contusive induced. sham group received only T10 laminectomy. Behavior testing (anxiety, motor/sensory function) performed for 6 weeks SCI....
Objective: We compared screening methods for asymptomatic venous thromboembolism (VTE) in patients with acute spine and spinal cord injuries (SCI). Patients were screened by D-dimer monitoring alone (DS group) or combined ultrasonography (DUS group).Design: Prospective cohort study.Setting: One department of a university hospital Japan.Participants: 114 treated SCI between 2011 2017.Interventions: N/A.Outcome Measures: D-dimers measured upon admission 1, 3, 5, 7, 14 days thereafter....
We categorized the four types of ossification posterior longitudinal ligament (OPLL) cervical spine into two groups. biochemically investigated genetic differences in osteogenic differentiation potency between groups.To investigate according to OPLL classification.Clinical studies on have revealed that risk progression area is greatest for continuous and mixed type OPLL. However, until now, these been studied as a single condition.We (continuous or type) segmental groups (segmental...
Multilineage-differentiating stress-enduring (Muse) cells are endogenous pluripotent stem that can be isolated based on stage-specific embryonic antigen-3 (SSEA-3), a cell-surface marker. However, their capacities for survival, neurotrophic factor secretion, and neuronal glial differentiation unclear in rodents. Here we analyzed mouse adipose tissue-derived Muse vitro. We collected mesenchymal (MSCs) from C57BL/6 J tissue separated SSEA-3 + , namely cells, – non-Muse to assess...
Abstract Background This cross-sectional study sought to determine the neck-shoulder stiffness/low back pain (NSS/LBP) comorbidity rate in a Japanese community population and compare quality of life (QOL) individuals with comorbid NSS/LBP, asymptomatic individuals, those symptoms NSS or LBP alone. Methods The sample included 1122 subjects (426 men; 696 women) previous 3 months, were grouped according NSS, LBP, (Comorbid), no (NP). They completed MOS 36-Item Short-Form Health Survey (SF-36)....
Ossification of the posterior longitudinal ligament (OPLL) is an ectopic bone formation in tissue spine, causing myelopathy as a result chronic pressure on spinal cord and nerve roots. It has been further categorized into 4 types, that is, segmental, continuous, mixed other types; however, differences detail progression ossification natural history disease among these types have not clarified.To find out systemic feature, which relevance to state OPLL.To characterize we conducted...
The purpose of this study was to investigate the relationship between postoperative enlargement dural sac cross-sectional area at symptomatic level and neurological improvements after laminoplasty.The areas before laminoplasty expansion ratio (post-/preoperative area) were measured using magnetic resonance imaging in patients with ossification posterior longitudinal ligament (OPLL) (n = 25) cervical spondylotic myelopathy (CSM) 49). relationships Japanese Orthopedic Association (JOA) score,...
Objective: To determine the incidence of venous thromboembolism (VTE) in patients with acute cervical spinal cord injury (SCI) and ossification posterior longitudinal ligament (OPLL).Design: Prospective cohort study.Setting: A department a university hospital Japan.Participants: This study included 57 (OPLL, n = 10; non-OPLL, 47) treated for SCI between January 2011 April 2017. Patients were classified according to motor complete paralysis (MC), incomplete (MIC), or normal function, based on...
A retrospective study.To compare long-term clinical and radiologic outcomes between conventional double-door laminoplasty (LP) (group A) cervical LP with C3 laminectomy B).Cervical preserving the semispinalis cervicis inserted into axis decreased patients' postoperative axial pain muscle atrophy, prevented interlaminar bony fusion, limitations of daily living activity, including reduced neck mobility, maintained range motion (ROM) more effectively than reattaching in short-term.Group...
Study Design. A retrospective comparison of the surgical outcome after cervical laminoplasty for spondylotic myelopathy (CSM) using a modified K-line based on lordosis in neck extension as predictor: Back CSM (KB group), crosses ventral edge any spinous processes, whereas Front (KF does not. Objective. To investigate neurological and radiological outcomes 5 years surgery contact between spinal cord posterior elements K-line. Summary Background Data. No indicators lateral radiograph can...
The physical and biochemical factors responsible for cervical disc degeneration, resulting in various spinal disorders, remain unclear. This study aimed to evaluate the correlation between canal stenosis degeneration of intervertebral discs, analyze related Japanese population.Three hundred forty-four general residents underwent investigations, including magnetic resonance imaging spine, our health check project. We measured anteroposterior diameters at levels mid sagittal plane evaluated...
The physical and biochemical factors related to cervical disc degeneration (CDD), which is involved in several spinal disorders, remain uncertain. We investigated associations between CDD muscle strength a general Japanese population. used mid-sagittal-plane MRIs assess 344 subjects recruited from participants our community health-check project, measured body mass index (BMI), skeletal (SMI), the neck, trunk, hands, legs. was scored based on prevalence severity of intravertebral...
Study Design. In vivo studies of the vascular system in ossification posterior longitudinal ligament (OPLL) model mice. Objective. The aim this study was to investigate blood coagulability, morphology, and vasculogenesis capability, known as venous thromboembolism (VTE) risk factors model, tiptoe walking (ttw) Summary Background Data. Patients with OPLL are more likely develop VTE after spinal cord injury. Capillary mesh invasion ligaments precedes ttw Investigation on systems mice may...
Mice with a knockout of phospholipase C (PLC)-related inactive protein type 1 (PRIP1-/- mice) display anxiety-like behavior and altered γ-aminobutyric acid (GABA)A-receptor pharmacology. Here, we examined associations between anxiety motor-function recovery in PRIP1-/- mice after spinal cord injury (SCI) induced by moderate contusion at the 10th thoracic level. Uninjured showed less distance than wild-type (WT) center 25% an open field test (OFT), indicating behavior. Anxiety increased both...
Retrospective study.We experienced the situation wherein some patients had new-onset pain or dysesthesia around ring and little fingers (C8 symptom) ulnar aspect of forearm (T1 after cervical laminoplasty (LP). We investigated incidence cause new C8 T1 symptoms clinical outcomes C3-C6 LP C3-C7 LP.There were reports regarding complications LP. However, there was no report LP.Among 33 enrolled in this study, 11 22 treated with LP, respectively. prospectively evaluated daily postoperatively for...