A5041942481- Dialysis and Renal Disease Management
- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Acute Kidney Injury Research
- Renal and related cancers
- Organ and Tissue Transplantation Research
- Organ Donation and Transplantation
- Chronic Kidney Disease and Diabetes
- Central Venous Catheters and Hemodialysis
- Renal Diseases and Glomerulopathies
- Pharmacological Effects and Toxicity Studies
- COVID-19 Clinical Research Studies
- Transplantation: Methods and Outcomes
- Electrolyte and hormonal disorders
- Hepatitis C virus research
- Metabolism and Genetic Disorders
- Diet and metabolism studies
- Renal function and acid-base balance
- COVID-19 Impact on Reproduction
- Chronic Myeloid Leukemia Treatments
- Liver Disease Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Pancreatic function and diabetes
- Diabetes Treatment and Management
- Healthcare cost, quality, practices
SUNY Downstate Health Sciences University
2013-2024
State University of New York
2012-2024
Cornell University
2024
Toledo Clinic Cancer Center
2023
Northwell Health
2002-2012
Staten Island University Hospital
2004
St. Luke's-Roosevelt Hospital Center
1999
Shriners Hospitals for Children - Galveston
1998
The University of Texas Medical Branch at Galveston
1995
Icahn School of Medicine at Mount Sinai
1990-1992
Patients with ESRD have high rates of depression, which is associated diminished quality life and survival. We determined whether individual cognitive behavioral therapy (CBT) reduces depression in hemodialysis patients elevated depressive affect a randomized crossover trial. Of 65 participants enrolled from two dialysis centers New York, 59 completed the study were assigned to treatment-first group (n=33) or wait-list control (n=26). In intervention phase, CBT was administered chairside...
Reimbursement for chronic dialysis consumes a substantial portion of healthcare costs relatively small proportion the total population. Each country has unique reimbursement system that attempts to control rising costs. Thus, comparing systems between countries might be helpful find solutions minimize society without jeopardizing quality treatment and outcomes. We conducted survey seven compare crude various modalities evaluated additional factors, such as inclusion drugs or physician...
Primary goal of this randomized, double-blind, placebo-controlled crossover study Renadyl in end-stage renal disease patients was to assess the safety and efficacy measured through improvement quality life or reduction levels known uremic toxins. Secondary investigate effects on several biomarkers inflammation oxidative stress.Two 2-month treatment periods separated by washout crossover, with physical examinations, venous blood testing, questionnaires completed at each visit. Data were...
Two metrics, a rise in serum creatinine concentration and decrease urine output, are considered tantamount to the injury of kidney tubule epithelial cells thereof (AKI). Yet neither criterion emphasizes etiology or pathogenetic heterogeneity acute decreases excretory function. In fact, whether decreased function due contraction extracellular fluid volume (vAKI) intrinsic (iAKI) actually share pathogenesis should be aggregated same diagnostic group remains an open question. To examine this...
Both mitogenic and inflammatory phenomena accompany the renal response to ischemic injury. Previous studies have shown that several nuclear-binding members of immediate early genes are prominently expressed after ischemia may underlie such We now report on expression JE KC, other growth-factor-responsive code for small secreted glycoproteins with cytokine-like properties, which play a role in inflammation. The KC was determined rat kidney tissue at varying time points release 50-min period...
A 41-year-old male with a history of chronic kidney disease, hypertension, and psoriasis was referred to the nephrologist for worsening function associated nephrotic range proteinuria. The patient had no symptoms, but initial workup showed elevated erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), positive double-stranded DNA antibody(anti-DsDNA) normal complement levels, antinuclear antibody (ANA) negative beta-glycoprotein-1 IgG, IgM, IgA. Further, revealed total...
Abstract. Increased urine flow is often a feature of mild to moderate acute renal failure. This study examines the possible role dysregulation collecting duct aquaporins as factor in this increase. In rats, left pedicle was clamped for 45 min followed by contralateral nephrectomy. Control rats were identical except that not clamped. Rats sacrificed and kidneys homogenized at various time points after release clamp semiquantitative immunoblotting aquaporins, well thick ascending limb Na-K-2Cl...
SUMMARY Background Sleep disorders and depression are prevalent conditions in patients with end‐stage kidney disease. These co‐morbidities have significant overlap compounded morbidity mortality burden. This presents challenges to optimal clinical assessment treatment. The goal of this study was assess the prevalence sleep disturbance on maintenance haemodialysis, impact depressive affect. Objectives a single‐site, single group, cross‐sectional 69 English‐speaking undergoing haemodialysis....
<b><i>Background:</i></b> The incidence and prevalence of Chronic Kidney Disease (CKD) is growing rapidly. Understanding the factors associated with declining renal function clinical significance. current study's main goal was to identify variables that could predict decline in glomerular filtration rate (GFR) over time outpatients varying stages CKD. <b><i>Methods:</i></b> Seventy CKD patients completed psychological questionnaires medical...
We have cloned and sequenced the cDNA corresponding to rat preproepidermal growth factor (ppEGF) mRNA. The contained 4,801 nucleotides, similar that reported for mouse (4,749 nucleotides) human mRNAs (4,871 nucleotides). predicted protein sequence would contain 1,133 amino acids, smaller than (1,217 acids) sequences (1,207 acids). results of sequencing several clones suggested existence more one structural gene ppEGF. In addition, there was an occurrence alternative splicing events,...
Epidermal growth factor (EGF) is a small polypeptide belonging to class of molecules that can mediate cell growth, differentiation, and acute phase responses. EGF mRNA transcribed primarily in cells the salivary gland kidney. We have found tissue cellular specificities gene expression are controlled by promoter region located upstream from start transcription. In variety experimentally induced forms renal failure, protein levels for kidney fall markedly remain low prolonged period. This...
Background: Coronavirus disease-19 (COVID-19) is associated with acute kidney injury (AKI) and respiratory distress syndrome (ARDS) high mortality rates. In African American (AA) populations, COVID-19 presentations outcomes are more severe. NIH Interim WHO guidelines had suggested against the use of corticosteroids unless in clinical trials until recent publication RECOVERY trial. Here, we analyzed treatment effect methylprednisolone on patients AKI ARDS during initial 2 months detail...
Journal Article Renal Failure Due to Leukaemic Infiltration in Chronic Lymphocytic Leukaemia Get access S. Saggi, Saggi 1Renal SectionNew York, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar C. Calandri, Calandri 2Hematology Section, Department of MedicineNew T. Muhlfelder, Muhlfelder H. Choi, Choi 3Department Pathology, Veterans Administration Medical Center, Bronx and Mount Sinai School Kahn, Kahn D. Kaji Correspondence offprint requests to: 1Deepak...