A5090855841- Vibrio bacteria research studies
- Genomics and Phylogenetic Studies
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Aquaculture disease management and microbiota
- Salmonella and Campylobacter epidemiology
- Mycobacterium research and diagnosis
- Diphtheria, Corynebacterium, and Tetanus
- Microbial Community Ecology and Physiology
- Bacterial Infections and Vaccines
- Mosquito-borne diseases and control
- Metal Extraction and Bioleaching
- Clostridium difficile and Clostridium perfringens research
- Parasite Biology and Host Interactions
- Infective Endocarditis Diagnosis and Management
- Identification and Quantification in Food
- Cancer-related gene regulation
- Bacteriophages and microbial interactions
- RNA modifications and cancer
- Respiratory viral infections research
- Insect symbiosis and bacterial influences
- Microbial Natural Products and Biosynthesis
- Microbial infections and disease research
- Parasitic Diseases Research and Treatment
- Viral-associated cancers and disorders
Universidad de La Frontera
2018-2025
Fundação Oswaldo Cruz
2011-2018
Universidade de Santiago de Compostela
2018
NOAA Atlantic Oceanographic and Meteorological Laboratories
2018
National Oceanic and Atmospheric Administration
2018
University of Miami
2018
Complejo Hospitalario Universitario de Santiago
2018
Complejo Hospitalario de Pontevedra
2018
Xunta de Galicia
2018
United States Food and Drug Administration
2018
Background The current millennium has seen a steep rise in the number, size and case-fatalities of cholera outbreaks many African countries. Over 40,000 cases were reported from Nigeria 2010. Variants Vibrio cholerae O1 El Tor biotype have emerged but very little is known about strains causing West Africa, which crucial for implementation interventions to control epidemic cholera. Methodology/Principal Findings V. isolates acute watery diarrhea December, 2009 October, 2010 identified by...
Abstract The Epstein-Barr virus (EBV) infects more than 90% of the human population, playing a key role in origin and progression malignant non-malignant diseases. Many attempts have been made to classify EBV according clinical or epidemiological information; however, these classifications show frequent incongruences. For instance, they use small subset genes for sorting strains but fail consider enormous genomic variability abundant recombinant regions present genome. These could lead...
Klebsiella pneumoniae, variicola and quasipneumoniae are difficult to differentiate phenotypically, leading misinterpretation of their infection prevalence. We propose a multiplex PCR for blaSHV, blaLEN blaOKP flanking gene (deoR). Since this scheme focuses only on chromosomal genes, it will be feasible identification in the clinical routine.
is the leading cause of seafood-related infections with illnesses undergoing a geographic expansion. In this process expansion, most fundamental change has been transition from caused by local strains to surge pandemic clonal types. Pandemic clone sequence type 3 (ST3) was only example transcontinental spreading until 2012, when ST36 detected outside region where it endemic in U.S. Pacific Northwest causing along northeast coast and Spain. Here, we used genome-wide analyses reconstruct...
Abstract Antarctic have been suggested as an attractive source for antibiotics discovery and members of Streptomyces genus historically studied natural producers antimicrobial metabolites. Nonetheless, our knowledge on antibiotic-producing from is very limited. In this study, the activity organic extracts strains was evaluated by disk diffusion assays minimum inhibitory concentration. The strain sp. So13.3 showed greatest antibiotic (MIC = 15.6 μg/mL) against Gram-positive bacteria growth...
Abstract We report transcontinental expansion of Vibrio parahaemolyticus sequence type 36 into Lima, Peru. From national collections, we identified 7 isolates from 2 different Pacific Northwest complex lineages that surfaced during 2011–2016. Sequence is likely established in environmental reservoirs. Systematic surveillance enabled detection these epidemic isolates.
The present study evaluated the effect of two inoculum concentrations on degradation crude oil by Corynebacterium stationis CsPe-1. To this end, treatment systems were utilized, each containing Davies Minimum Medium, 1% oil, and bacterial at 10% 15%, respectively. degree biodegradation was determined evaluating biochemical oxygen demand (BOD5), chemical (COD), concentration fractions grease, total petroleum hydrocarbons (TPH). results indicated that both BOD5 COD exhibited an increase after...
Galicia in northwestern Spain has been considered a hotspot for Vibrio parahaemolyticus infections. Infections abruptly emerged 1998 and, over the next 15 years, were associated with large outbreaks caused by strains belonging to single clone. We report recent transition epidemiologic pattern which cases throughout region have linked different and unrelated strains. Global genome-wide phylogenetic analysis revealed that most of pathogenic isolated from infections globally diverse isolates,...
This study aimed to characterize the genomic context of bla SPM-1 gene in Brazilian strains belonging pandemic Pseudomonas aeruginosa clone SP/ST277.WGS SP/ST277 was performed using a Nextera paired-end library an Illumina HiSeq 2500 sequencer. assessed by de novo assembly and prediction annotation tools. screened P. genomes through BlastN, comparative genomics were performed.The metallo-β-lactamase has been disseminated SP/ST277. In spite its association with CR4 element Tn4371 element,...
Klebsiella species frequently cause clinically relevant human infections worldwide. We report the draft genome sequence of a Brazilian clinical isolate (Bz19) recently recognized variicola. The comparison Bz19 content with At-22 (environmental K. variicola) and several pneumoniae shows that these share set virulence-associated determinants. Of note, this variicola strain harbours plasmid-like element shares same backbone present in multidrug-resistant plasmid found isolated USA.
Shewanella is a microbial group with high potential to be applied in textile effluents bioremediation due its ability use wide variety of substrates as final electron acceptor respiration. The present research aimed describe new strain, algae 2NE11, decolorizing bacterium isolated from industrial effluent Peru. S. 2NE11 showed an optimal growth under pH 6-9, temperature between 30-40 °C, and 0-4 % NaCl. It can tolerate concentrations NaCl until 10% low temperatures 4 °C. decolorizes azo...
BackgroundHuman metapneumovirus (HMPV) is an important aetiologic agent of respiratory tract infection (RTI). This study aimed to describe the prevalence, genetic diversity, and evolutionary dynamics HMPV.MethodsLaboratory-confirmed HMPV were characterised based on partial-coding G gene sequences with MEGA.v6.0. WGS was performed Illumina, analyses Datamonkey Nextstrain.ResultsHMPV prevalence 2.5%, peaking in February-April alternation predominance HMPV-A –B until emergence SARS-CoV-2, not...
Abstract Actinomycetota have been widely described as valuable sources for the acquisition of secondary metabolites. Most microbial metabolites are produced via metabolic pathways encoded by biosynthetic gene clusters (BGCs). Although many not essential survival bacteria, they play an important role in their adaptation and interactions within communities. This is how bacteria isolated from extreme environments such Antarctica could facilitate discovery new BGCs with biotechnological...
<ns4:p>The identification of the clinically relevant viridans streptococci group, at species level, is still problematic. The aim this study was to extract taxonomic information from complete genome sequences 67 streptococci, comprising 19 species, by means genomic analyses, multilocus sequence analysis (MLSA), average amino acid identity (AAI), signatures, genome-to-genome distances (GGD) and codon usage bias. We then attempted determine usefulness these tools for in streptococci. Our...
Despite the broad distribution of M. ozzardi in Latin America and Caribbean, there is still very little DNA sequence data available to study this neglected parasite's epidemiology. Mitochondrial (mtDNA) sequences, especially cytochrome oxidase (CO1) gene's barcoding region, have been targeted successfully for filarial diagnostics epidemiological, ecological evolutionary studies. MtDNA-based studies can, however, be compromised by unrecognised mitochondrial pseudogenes, such as Numts. Here,...
Vibrio cholerae is a globally dispersed pathogen that has evolved with humans for centuries, but also includes non-pathogenic environmental strains. Here, we identify the genomic variability underlying this remarkable persistence across three major niche dimensions space, time, and habitat. Taking an innovative approach of genome-wide association applicable to microbial genomes (GWAS-M), classify 274 complete V. by niche, including 39 newly sequenced study Ion Torrent DNA-sequencing...
Colorectal cancer is a heterogeneous disease caused by both genetic and epigenetics factors. Analysing DNA methylation changes occurring during colorectal progression metastasis formation crucial for the identification of novel epigenetic markers patient prognosis. Genome-wide sequencing paired samples colon (normal adjacent, primary tumour lymph node metastasis) showed global hypomethylation CpG island (CGI) hypermethylation tumours compared to normal. In we observed high non-CGI regions...
In recent years, the frequency of cholera epidemics across Africa has increased significantly with thousands people dying each year. However, there still exists a lack information concerning Vibrio cholerae O1 lineages driving early and contemporary since seventh pandemic started in continent. This compromises understanding forces determining epidemiology its control. study aimed to analyze collection V. strains from beginning Ghana compare them isolates understand evolution epidemic Ghana....
In the last decades, there has been an increase of cholera epidemics caused by multidrug resistant strains. Particularly, integrative and conjugative element (ICE) seems to play a major role in emergence Vibrio cholerae. This study fully characterized, whole genome sequencing, new ICEs carried V. cholerae O1 strains from Nigeria (2010) (ICEVchNig1) Nepal (1994) (ICEVchNep1). The gene content order these two are same, identical ICEVchInd5, ICEVchBan5 ICEVchHai1 previously identified O1. ICE...
Chikungunya virus (CHIKV) is a mosquito-borne pathogen that emerged in Brazil by late 2014. In the country, two CHIKV foci characterized East/Central/South Africa and Asian genotypes, were established North Northeast regions. We characterized, phylogenetic analyses of full partial genomes, from Rio de Janeiro state (2014-2015). These strains belong to genotype, which determinant current Northern Brazilian focus, even though genome sequence presents particular single nucleotide variations....
Ovarian cancer is a significant cancer-related cause of death in women worldwide. The most used chemotherapeutic regimen based on carboplatin (CBDCA). However, CBDCA resistance the main obstacle to better prognosis. An vitro drug-resistant cell model would help understanding molecular mechanisms underlying this drug-resistance phenomenon. aim study was characterize cellular and changes induced CBDCA-resistant ovarian line A2780. selection strategy dose-per-pulse method using concentration...