A5101881511- Epilepsy research and treatment
- Neonatal and fetal brain pathology
- Metabolism and Genetic Disorders
- Neuroscience and Neuropharmacology Research
- Pharmacological Effects and Toxicity Studies
- EEG and Brain-Computer Interfaces
- Diet and metabolism studies
- Anesthesia and Neurotoxicity Research
- Viral Infections and Immunology Research
- Genetics and Neurodevelopmental Disorders
- Blind Source Separation Techniques
- MicroRNA in disease regulation
- Cytomegalovirus and herpesvirus research
- Ion channel regulation and function
- Adipose Tissue and Metabolism
- Bacterial Infections and Vaccines
- interferon and immune responses
- Molecular Biology Techniques and Applications
- Neuroinflammation and Neurodegeneration Mechanisms
- Geotechnical Engineering and Analysis
- ATP Synthase and ATPases Research
- Mitochondrial Function and Pathology
- Geotechnical Engineering and Underground Structures
- Traumatic Brain Injury and Neurovascular Disturbances
- Landslides and related hazards
Sichuan Agricultural University
2023-2025
Ministry of Agriculture and Rural Affairs
2023-2025
Shanghai Children's Medical Center
2016-2025
Shanghai Jiao Tong University
2017-2025
Jiangnan University
2024
State Grid Corporation of China (China)
2024
Chongqing University
2021-2024
Wuxi Fourth People's Hospital
2024
Xuzhou Medical College
2024
Chang'an University
2023
Abstract Peripheral CD8 + T cell number is tightly controlled but the precise molecular mechanism regulating this process still not fully understood. In study, we found that epilepsy patients with loss of function mutation DEPDC5 had reduced peripheral cells, and expression positively correlated tumor-infiltrating cells as well overall cancer patient survival, indicating may control homeostasis. Significantly, mice cell-specific Depdc5 deletion also impaired anti-tumor immunity....
The automatic identification of epileptic EEG signals is significant in both relieving heavy workload visual inspection recordings and treatment epilepsy. This paper presents a novel method based on the theory sparse representation to identify EEGs. At first, raw epochs are preprocessed via Gaussian low pass filtering differential operation. Then, scheme classification (SRC), test sample sparsely represented training set by solving l 1 -minimization problem, residuals associated with ictal...
Lung cancer is the leading cause of cancer-related death in world. To explore tumor biomarkers for clinical application, two-dimensional fluorescence difference gel electrophoresis and subsequent MALDI-TOF/TOF mass spectrometry were performed to identify proteins differentially expressed 12 pairs lung squamous cell tumors their corresponding normal tissues. A total 28 nonredundant identified with significant alteration tumors. The up-regulation isocitrate dehydrogenase 1 (IDH1), superoxide...
The feature analysis of epileptic EEG is very significant in diagnosis epilepsy. This paper introduces two nonlinear features derived from fractal geometry for analysis. blanket dimension and intercept are extracted to characterize behavior activities, then their discriminatory power ictal interictal EEGs compared by means statistical methods. It found that there difference the between EEGs, more noticeable than feature. Furthermore, these at multi-scales combined with support vector machine...
The present study aimed to identify potential key genes and pathways in obese children order explore possible molecular mechanisms associated with child obesity. array dataset GSE29718 was downloaded from the Gene Expression Omnibus database. Subcutaneous adipose tissue samples derived 7 8 lean were selected for analysis. Differentially expressed (DEGs) compared those analyzed by limma package. ontology (GO) annotation, Kyoto Encyclopedia of Genes Genomes Reactome pathway enrichment analyses...
Semen quality has an important impact on the reproductive performance of ganders, and quantity spermatozoa in semen are determinants quality. In our practical work, a small number azoospermic ganders were observed adult goose breeding populations, but underlying regulatory mechanisms remain unknown. present study, we firstly compared morphological histological differences testes from normozoospermic group (NG) (AG), then analyzed testicular expression patterns circRNAs, miRNAs, mRNAs between...
Automatic seizure detection is of great significance in the monitoring and diagnosis epilepsy. In this study, a novel method proposed for automatic intracranial electroencephalogram (iEEG) recordings based on kernel collaborative representation (KCR). Firstly, EEG are divided into 4s epochs, then wavelet decomposition with five scales performed. After that, detail signals at 3, 4 5 selected to be sparsely coded over training sets using KCR. KCR, l 2 -minimization replaces 1 sparse...
Presently, excessive fat deposition is the main reason to limit development of duck industry. In production, methods restricted feeding (RF) were widely used reduce lipid ducks. The liver (L), abdominal adipose (AA), and subcutaneous (SA) tissues metabolism However, mechanisms ducks under RF have not been fully clarified. this study, in order better understand RF, a total 120 male Nonghua randomly divided into free group (FF, n = 60) (RF, 60), then comparative transcriptomic analysis L, AA,...
Brown adipose tissue (BAT) plays a critical role in regulating cardiovascular homeostasis through the secretion of adipokines, such as fibroblast growth factor 21 (FGF21). Dexmedetomidine (DEX) is selective α2-adrenergic receptor agonist with protection against myocardial ischemia/reperfusion injury (MI/RI). It remains largely unknown whether or not BAT-derived FGF21 involved DEX-induced cardioprotection context MI/RI. Herein, we demonstrated that DEX alleviated MI/RI and improved heart...